Formation constants of metal complexes of substituted benzimidazoles with different bivalent metal ions was written by Murthy, A. Krishna;Lingaiah, P.. And the article was included in Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical & Analytical in 1984.COA of Formula: C8H8N2 This article mentions the following:
The formation constants of the complexes of 4 (or 7)-methylbenzimidazole, 2-(2′-hydroxyphenyl)benzimidazole, 2-(2′-hydroxy-5′-bromophenyl)benzimidazoles, 2-(2′-hydroxy-3′-methoxy)benzimidazole, 2-(1′-hydroxyethyl)benzimidazole with Mn(II), Co(II), Ni(II), Cu(II), Zn(II), and Cd(II) were determined pH-metrically at different ionic strengths, temperatures, and in solutions of varying dielec. constant The results show that the metal ion reacts with the neutral ligand in the 1st stage and with the anionic ligand in the second stage. In the experiment, the researchers used many compounds, for example, 7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6COA of Formula: C8H8N2).
7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.COA of Formula: C8H8N2
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem