Effect of 4-amino-5-imidazolecarboxamide and related compounds on the growth of Entamoeba histolytica was written by Nakamura, Mitsuru. And the article was included in Canadian Journal of Microbiology in 1957.Application of 26832-08-6 This article mentions the following:
4-Amino-5-imidazolecarboxamide and 4-amino-5-imidazolecarboxamidine were found to be stimulatory to E. histolytica (NRS strain) when studied under bacteria-free conditions. These compounds in combination with folic acid or leucovorin, adenosinetriphosphate, and ribose-5-phosphate greatly stimulated amebic multiplication. Growth was measured qualitatively. In the experiment, the researchers used many compounds, for example, 1H-Imidazole-4-carboxamide (cas: 26832-08-6Application of 26832-08-6).
1H-Imidazole-4-carboxamide (cas: 26832-08-6) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Application of 26832-08-6
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem