Amino-catalyzed hydrolysis of amides and esters in the fragmentation by electrospray ionization tandem mass spectrometry using an ion trap was written by Yang, Xiaoli;Zhu, Changjin;Cao, Shuxia;Liao, Xinchen;Jiang, Yanfeng;Zhao, Yufen. And the article was included in Rapid Communications in Mass Spectrometry in 2003.Recommanded Product: 169770-25-6 This article mentions the following:
Neutral mass losses from mass-selected precursors in the ESI-MS/MS of monoimidazole polyamine amides and monoimidazole esters were attributed to hydrolysis by water (in the ion trap) and catalyzed by intramol. amino groups. In the experiment, the researchers used many compounds, for example, Methyl 1-methyl-4-nitro-1H-imidazole-2-carboxylate (cas: 169770-25-6Recommanded Product: 169770-25-6).
Methyl 1-methyl-4-nitro-1H-imidazole-2-carboxylate (cas: 169770-25-6) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Recommanded Product: 169770-25-6
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem