N-Trifluoromethylthio-dibenzenesulfonimide: A Shelf-Stable, Broadly Applicable Electrophilic Trifluoromethylthiolating Reagent was written by Zhang, Panpan;Li, Man;Xue, Xiao-Song;Xu, Chunfa;Zhao, Qunchao;Liu, Yafei;Wang, Haoyang;Guo, Yinlong;Lu, Long;Shen, Qilong. And the article was included in Journal of Organic Chemistry in 2016.Related Products of 25045-82-3 This article mentions the following:
The super electrophilicity of a shelf-stable, easily prepared trifluoromethylthiolating reagent N-trifluoromethylthio-dibenzenesulfonimide I was demonstrated. Consistent with the theor. prediction, I exhibits reactivity remarkably higher than that of other known electrophilic trifluoromethylthiolating reagents. In the absence of any additive, I reacted with a wide range of electron-rich arenes and activated heteroarenes under mild conditions. Likewise, reactions of I with styrene derivatives can be fine-tuned by simply changing the reaction solvents to generate trifluoromethylthiolated styrenes or oxo-trifluoromethylthio or amino-trifluoromethylthio difunctionalized compounds in high yields. In the experiment, the researchers used many compounds, for example, 6-Nitroimidazo[1,2-a]pyridine (cas: 25045-82-3Related Products of 25045-82-3).
6-Nitroimidazo[1,2-a]pyridine (cas: 25045-82-3) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Related Products of 25045-82-3
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem