Month: December 2022

Ouyang, Xinhua published the artcileEnhanced efficiency in nondoped, blue organic light-emitting diodes utilizing simultaneously local exciton and two charge-transfer exciton from benzimidazole-based donor-acceptor molecules, COA of Formula: C19H14N2, the publication is Dyes and Pigments (2014), 39-49, database is CAplus.

The simultaneous utilization of all charge-transfer excitons and local excitons is the pathway to obtain the high efficiency fluorescent organic light-emitting diodes (FOLEDs). Here, a twisted intramol. charge transfer state (TICT-state), a planar intramol. charge transfer state (ICT-state), and a locally excited state (LE-state) are demonstrated to enhance the occurrence of singlet excitons in the fluorescent emitters, which are based on benzimidazole and triphenylamine donor-acceptor derivatives The synthesis, photophysics and electroluminescent (EL) performance are studied systematically. The fluorescence emitters (TPABBBI and TPABBI) with the special TICT and ICT characteristics realize the electron-hole (e-h) recombination via intramol. conversion from charge-transfer excitons to radiative singlet exciton. The devices based on them show high efficiency (5.1 cd/A, 5.77 lm/W, 5.66% of EQE_m for TPABBBI and 3.56 cd/A, 3.11 lm/W, 4.23% for TPABBI), low efficiency roll-off at high luminance and stable blue emission.

Dyes and Pigments published new progress about 2622-67-5. 2622-67-5 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Benzene,Benzimidazole, name is 1,2-Diphenyl-1H-benzo[d]imidazole, and the molecular formula is C19H14N2, COA of Formula: C19H14N2.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Chen, Yong-kang published the artcileStudy of methodology validation of detection sodium content in esomeprazole sodium, Related Products of imidazoles-derivatives, the publication is Huaxue Gongchengshi (2016), 30(4), 67-70, database is CAplus.

In this paper, the at. absorption spectrometry (AAS) method for the determination of sodium in esomeprazole sodium was established. Using the standard curve method, the detection wavelength was 589.0 nm. Exptl. results show that at 589.0 nm the blank solution has no interference with the determination of sodium, linear study shows that the concentration of sodium within 0.5∼4.0 mg·L^-1 range, the absorbance A has a good linear relationship with the concentration of C, and R² is greater than 0.999. By method validation: accuracy, solution stability, repeatability and accuracy are good, at the same time this method has good durability and can be used as the determination method of sodium content in esomeprazole sodium.

Huaxue Gongchengshi published new progress about 161796-78-7. 161796-78-7 belongs to imidazoles-derivatives, auxiliary class Membrane Transporter/Ion Channel,Proton Pump, name is Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide, and the molecular formula is C17H18N3NaO3S, Related Products of imidazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Zhou, Yan published the artcileSuper-rapid and highly-efficient esterification of cellulose to achieve an accurate chromatographic analysis of its molecular weight, Recommanded Product: 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, the publication is Carbohydrate Polymers (2022), 119301, database is CAplus and MEDLINE.

Herein, a striking anion-tunnel transfer effect was demonstrated in 1-butyl-3-methylimidazolium benzoate (BmimPhCOO) ionic liquid, so a rapid, mild and efficient benzoylation of cellulose is accomplished under catalyst-free condition in BmimPhCOO. In a wide temperature range of 20-80°C, the equilibrium of reaction is reached within only 15 min, which is much faster than the reported acylation of cellulose. Furthermore, the resultant cellulose tribenzoates have excellent solubility in conventional organic solvents, thus they can be used to accurately reflect the mol. weight and dispersity index of cellulose raw materials by gel permeation chromatog. This method is suitable for various cellulose. Therefore, we found a new principle to realize the extremely-rapid acylation of cellulose, and proposed an effective approach to accurately determine the mol. weight parameters of cellulose.

Carbohydrate Polymers published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C18H24N6O6S4, Recommanded Product: 3-Butyl-1-methyl-1H-imidazol-3-ium chloride.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Song, Wei-guo published the artcileSynthesis of esomeprazole sodium, COA of Formula: C17H18N3NaO3S, the publication is Zhongguo Yaowu Huaxue Zazhi (2013), 23(4), 286-288, database is CAplus.

Esomeprazole was the first optical isomer proton pump inhibitor, and its sodium salt was applied to the patients who are in need of PPI but not capable of oral dosing. At present, there were three methods to synthesize esomeprazole such as omeprazole racemic resolution, omeprazole sulfide complexes asym. catalytic oxidation and biochem. oxidation However, the omeprazole racemic resolution was limited industrially due to its high cost and low yield. The aim of this study was to propose a modified asym. oxidation method to prepare esomeprazole for industrialized production Compared with the traditional method, this new method had three advantages. Firstly, the (1S, 2S)-(-)-1,2-diaminocyclohexane D-tartrate was used as chiral ligands, which avoided the addition of organic alkali in the traditional route. Secondly, cobalt naphthenate was applied as the catalyst to solve the problem of water-contacting over traditional titanium catalyst. Lastly, sodium peroxide was not only the oxidant to lower the cost of asym. oxidizing the omeprazole sulfide compounds but also the source of sodium for no more addition of other sodium source.

Zhongguo Yaowu Huaxue Zazhi published new progress about 161796-78-7. 161796-78-7 belongs to imidazoles-derivatives, auxiliary class Membrane Transporter/Ion Channel,Proton Pump, name is Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide, and the molecular formula is C20H17FO4S, COA of Formula: C17H18N3NaO3S.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Zhang, Xiaofang published the artcileGuiding cellular channels of artificial nanohybrid woods for anisotropic properties and solar-thermal evaporation, Related Products of imidazoles-derivatives, the publication is Chemical Engineering Journal (Amsterdam, Netherlands) (2022), 132060, database is CAplus.

Natural evolution offers woods with intriguing multicomponent and anisotropic cellular structures, and endows super physicochem. properties. In order to compete with natural woods, many types of artificial woods were endeavored from polymers to achieve on-demand structures and functionalities. In most cases, production of oriented channels in mimic of wood lumina relied on a delicate unidirectional freeze-drying approach and utilization of volatile solvents. Herein we showed that artificial woods with controllable channel orientation could be produced from polymers in involatile solvents without particular control of freezing parameters. By dissolving cellulose in ionic liquid, oriented channels (diameter of 250-540μm) were produced through diffusion-induced phase separation and strengthened through a facile freezing and air-drying process. The compressive strength could reach 5.5 MPa at the strain of 15% along the channel direction. With the presence of structural anisotropy, incorporation of low-dimension nanomaterials offered the design flexibility in adding super properties in mechanics, water transportation, solar-thermal effect, thermal and photo conductance. For example, artificial hybrid woods with carbon nanotubes showed super solar-thermal property. When combining with the water-transporting ability of oriented channels, it was promising to design an efficient solar-thermal evaporator (5.88 kg m^-2 h^-1 under equivalent 3-sun irradiation). Thus, this study not only suggests an unprecedented approach of producing artificial woods from polymers in involatile solvents, but also offers the flexibility of designing microstructures and functionalities of artificial woods for various applications.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about 79917-90-1. 79917-90-1 belongs to imidazoles-derivatives, auxiliary class Ionic Liquid,Ionic Liquid, name is 3-Butyl-1-methyl-1H-imidazol-3-ium chloride, and the molecular formula is C18H26ClN3O, Related Products of imidazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Zheng, Jianwei published the artcileNovel core-shell nanocomposite as an effective heterogeneous catalyst for the synthesis of benzimidazoles, SDS of cas: 2622-67-5, the publication is Nanotechnology (2021), 32(26), 265603, database is CAplus and MEDLINE.

An effective heterogeneous catalyst for the synthesis of benzimidazole by integrating acidic catalytic activity and promoted the aerobic oxidation and magnetic recyclability of core-shell nanocomposite Fe₃O₄@SiO₂@UiO-66 was designed. The Fe₃O₄@SiO₂ core was encapsulated by the in-situ-grown UiO-66 shell and the UiO-66 shell retains the porous structure and crystallinity of UiO-66 with abundant exposed Lewis acid sites. It showed high catalytic ability for the synthesis of various benzimidazoles through the acid-catalyzed condensation and aerobic oxidation with in-situ oxygen. The Fe₃O₄@SiO₂ core provided magnetic recyclability of Fe₃O₄@SiO₂@UiO-66 and maintains high catalytic ability and stability over six cycles.

Nanotechnology published new progress about 2622-67-5. 2622-67-5 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Benzene,Benzimidazole, name is 1,2-Diphenyl-1H-benzo[d]imidazole, and the molecular formula is C7H7IN2O, SDS of cas: 2622-67-5.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Zhang, Qian published the artcileDetermination of the content of esomeprazole sodium for injection by HPLC, COA of Formula: C17H18N3NaO3S, the publication is Heilongjiang Yiyao (2016), 29(3), 383-385, database is CAplus.

Objective: To establish the content determination method of Esomeprazole Sodium for Injection by HPLC. Methods: Using Extend C18 Aglient column, the mobile phase was acetonitrile-pH 7.4 phosphate buffer solution-tetrabutylammonium hydrogen sulfate solution (28:67:5), the detection wavelength was at 302 nm. Results: linear range was 10.24-102.40μg/mL, the average recovery rate was 99.71%, and RSD was 0.71%. Conclusion: this method was reliable and accurate, and could be used for the quality control of the preparation

Heilongjiang Yiyao published new progress about 161796-78-7. 161796-78-7 belongs to imidazoles-derivatives, auxiliary class Membrane Transporter/Ion Channel,Proton Pump, name is Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide, and the molecular formula is C12H15NO, COA of Formula: C17H18N3NaO3S.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Zhang, Qian published the artcileDetermination of the content of esomeprazole sodium for injection by HPLC, Recommanded Product: Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide, the publication is Heilongjiang Yiyao (2016), 29(3), 383-385, database is CAplus.

Objective: To establish the content determination method of Esomeprazole Sodium for Injection by HPLC. Methods: Using Extend C18 Aglient column, the mobile phase was acetonitrile-pH 7.4 phosphate buffer solution-tetrabutylammonium hydrogen sulfate solution (28:67:5), the detection wavelength was at 302 nm. Results: linear range was 10.24-102.40 μg/mL, the average recovery rate was 99.71%, and RSD was 0.71%. Conclusion: this method was reliable and accurate, and could be used for the quality control of the preparation

Heilongjiang Yiyao published new progress about 161796-78-7. 161796-78-7 belongs to imidazoles-derivatives, auxiliary class Membrane Transporter/Ion Channel,Proton Pump, name is Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide, and the molecular formula is 0, Recommanded Product: Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Han, Jie published the artcile2-Chloromethyl-1-methyl-1,3-benzimidazole, Related Products of imidazoles-derivatives, the publication is Acta Crystallographica, Section E: Structure Reports Online (2011), 67(8), o2104, database is CAplus and MEDLINE.

The title compound, C₉H₉ClN₂, was prepared from the reaction of N-methylbenzene-1,2-diamine and 2-chloroacetic acid in boiling 6 M hydrochloric acid. The benzimidazole unit is approx. planar, the largest deviation from the mean plane being 0.008(1) Å. The Cl atom is displaced by 1.667(2) Å from this plane. The Me group is statistically disordered with equal occupancy.

Acta Crystallographica, Section E: Structure Reports Online published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C9H9ClN2, Related Products of imidazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Jiang, Jun-hao published the artcileTheoretical studies on the structures and ECD spectra of S isomer of PPIs, Recommanded Product: Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide, the publication is Sichuan Daxue Xuebao, Ziran Kexueban (2013), 50(1), 125-130, database is CAplus.

Sodium salts of omeprazole, lansoprazole, pantoprazole, rabeprazole and ilaprazole are proton pump inhibitors(PPIs) containing the chiral sulfoxide, so each has a pair of enantiomers. In order to understand the electronic structures of above five PPIs, the d. functional theory(DFT) and the polarizable continuum model(PCM) were performed on the S isomers in water at B3LYP/6-311++G** level. On this basis, the ECD spectra of these mols. were studied using the time-dependent d. functional theory(TD-DFT) at the same level. The calculation results demonstrate two conclusions: in the S isomers of above five PPIs, the bond critical points indicating the formation of the bonds exists between Na(21) and N(11), and the similar phenomenon exists between Na(21) and O(2); S-omeprazole sodium and S-ilaprazole sodium have the similar ECD spectrum, both having neg. CD absorption bands near 300 nm mainly derived from π->π* charge transition, besides S-Ilaprazole sodium having a pos. cotton effect mainly derived from π->d charge transition of benzimidazole ring to Na(21); S-Lansoprazole sodium, S-Pantoprazole sodium and S-Rabeprazole sodium have the similar ECD spectrum, having two neg. CD absorption bands at 230 and 300 nm both mainly derived from the π->π* charge transition.

Sichuan Daxue Xuebao, Ziran Kexueban published new progress about 161796-78-7. 161796-78-7 belongs to imidazoles-derivatives, auxiliary class Membrane Transporter/Ion Channel,Proton Pump, name is Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide, and the molecular formula is C17H18N3NaO3S, Recommanded Product: Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem