COSMOTherm as a Tool for Estimating the Thermophysical Properties of Alkylimidazoles as Solvents for CO2 Separations was written by Bara, Jason E.;Moon, Joshua D.;Reclusado, Kristofer R.;Whitley, John W.. And the article was included in Industrial & Engineering Chemistry Research in 2013.Quality Control of 1-Octyl-1H-imidazole This article mentions the following:
The imidazole core is a versatile building block for a variety of materials including pharmaceuticals, ionic liquids, and polymers. While the thermophys. properties of ionic liquids and their application as solvents for CO2 separations have been the focus of a broad research effort for more than a decade, studies on properties and applications of imidazoles (from which many ILs are synthesized) have begun only recently. Similar to ILs, the phys. and chem. properties of imidazoles can also be tuned via mol. design strategies, resulting in a vast array of possible structures. This immense exptl. space necessitates the use of a rapid means of predicting thermophys. properties to guide the design of future solvents and gain fundamental insights into structure-property relationships. To this end, we have employed COSMOTherm as a means of rapidly screening properties of alkylimidazoles relevant to CO2 separation processes and comparing these calculated values to exptl. results. Results indicate that COSMOTherm is an effective and accurate tool for predicting the properties of smaller alkylimidazoles (e.g., 1-methylimidazole), but in many cases is much less accurate for the larger alkylimidazoles. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Quality Control of 1-Octyl-1H-imidazole).
1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Quality Control of 1-Octyl-1H-imidazole
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem