Phase Equilibrium Investigation on 2-Phenylethanol in Binary and Ternary Systems: Influence of High Pressure on Density and Solid-Liquid Phase Equilibrium was written by Domanska, Urszula;Krolikowski, Marek;Wlazlo, Michal;Wieckowski, Mikolaj. And the article was included in Journal of Physical Chemistry B in 2018.Formula: C18H31F6N3O4S2 This article mentions the following:
Ionic liquids (ILs) are important new solvents proposed for applications in different separation processes. Herein, an idea of possible use of high pressure in a general strategy of production of 2-phenylethanol (PEA) is discussed. In this work, we present the influence of pressure on the d. in binary systems of 1-hexyl-1-methylpyrrolidynium bis{(trifluoromethyl)sulfonyl}imide, [HMPYR][NTf2], or 1-dodecyl-3-methylimidazolium bis{(trifluoromethyl)sulfonyl}imide, [DoMIM][NTf2] + PEA in a wide range of temperatures (298.15-348.15 K) and pressures (0.1-40 MPa). The densities at ambient and high pressures are measured to present the physicochem. properties of the ILs used in the process of separation of PEA from aqueous phase. The Tait equation was used for the correlation of d. of one-component and two-component systems as a function of mole fraction, temperature, and pressure. The influence of pressure is not significant. These systems exhibit mainly neg. molar excess volumes, VE. The solid-liquid phase equilibrium (SLE) of [DoMIM][NTf2] in PEA at atm. pressure was measured and compared to the SLE high-pressure results. Addnl., the ternary liquid-liquid phase equilibrium (LLE) at ambient pressure in the {[DoMIM][NTf2] (1) + PEA (2) + water (3)} at temperature T = 308.15 K was investigated. The solubility of water in the [DoMIM][NTf2] is quite high in comparison with that measured by us earlier for ILs (x3 = 0.403) at T = 308.15 K, which results in not very successful average selectivity of extraction of PEA from the aqueous phase. The [DoMIM][NTf2] has shown strong interaction with PEA without the immiscibility region. The ternary system revealed Treybal’s type phase equilibrium in which two partially miscible binaries ([DoMIM][NTf2] + water) and (PEA + water) exist. From the results of LLE in the ternary system, the selectivity and the solute distribution ratio of separation of water/PEA were calculated and compared to the results obtained for the ILs measured earlier by us. The popular NRTL model was used to correlate the exptl. tie-lines in ternary LLE. These results may help in a new technol. project of “in situ” extraction of PEA from aqueous phase during the biosynthesis. In the experiment, the researchers used many compounds, for example, 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5Formula: C18H31F6N3O4S2).
3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Formula: C18H31F6N3O4S2
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem