Assessing chemical toxicity of ionic liquids on Vibrio fischeri: Correlation with structure and composition was written by Montalban, Mercedes G.;Hidalgo, Juana M.;Collado-Gonzalez, Mar;Diaz Banos, F. Guillermo;Villora, Gloria. And the article was included in Chemosphere in 2016.Application In Synthesis of 1-Methyl-1H-imidazol-3-ium chloride This article mentions the following:
One of the most important properties of ionic liquids is their non-volatility, making them potentially “green” alternatives to volatile organic compounds However, they are widely soluble in water, meaning that they can be released into aquatic ecosystems and so contribute to water pollution. Nevertheless, although the toxicity of ILs has been widely assessed in the literature, the information is still scarce due to the great number of ionic liquids that have been synthesized. The present work reports the toxicity of twenty-nine imidazolium-, pyridinium- and ammonium-based ionic liquids towards the bioluminescent photobacterium Vibrio fischeri. When the effect of the type of anion, the length of the alkyl chain of the cation, the cation core and the presence of a functionalized side chain in the cation on ionic liquid toxicity were analyzed, the main influence was seen to be exercised by the alkyl chain length. A Quant. Structure-Activity Relationships-based method was used to compare the exptl. results with previously estimated values and very good agreement was obtained. A relationship between the toxicity, expressed as Log EC50, and the 1-octanol-water partition coefficient was established. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Application In Synthesis of 1-Methyl-1H-imidazol-3-ium chloride).
1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Application In Synthesis of 1-Methyl-1H-imidazol-3-ium chloride
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem