Synthesis and biological activity of N-acylmethyl derivatives of 9H-2,3-dihydroimidazo- and 10H-2,3,4,10-tetrahydropyrimido[1,2-a]benzimidazoles and their reduction products was written by Anisimova, V. A.;Tolpygin, I. E.;Spasov, A. A.;Kosolapov, V. A.;Stepanov, A. V.;Kucheryavenko, A. F.. And the article was included in Pharmaceutical Chemistry Journal in 2006.Recommanded Product: 2,3-Dihydro-1H-benzo[d]imidazo[1,2-a]imidazole This article mentions the following:
A series of N-acylmethyl derivatives of 9H-2,3-dihydroimidazo- and 10H-2,3,4,10-tetrahydropyrimido[1,2-a]benzimidazoles and products of their reduction has been synthesized and their pharmacol. properties have been studied. Most of the synthesized substances possess weak antioxidant activity. At the same time, they exhibit pronounced antiaggregant and hemorheol. properties, possess spasmolytic activity, and influence the blood glucose level. In the experiment, the researchers used many compounds, for example, 2,3-Dihydro-1H-benzo[d]imidazo[1,2-a]imidazole (cas: 24134-26-7Recommanded Product: 2,3-Dihydro-1H-benzo[d]imidazo[1,2-a]imidazole).
2,3-Dihydro-1H-benzo[d]imidazo[1,2-a]imidazole (cas: 24134-26-7) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Recommanded Product: 2,3-Dihydro-1H-benzo[d]imidazo[1,2-a]imidazole
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem