Alkylation of 4(5)-substituted imidazoles was written by Benjes, Paul;Grimmett, Ross. And the article was included in Heterocycles in 1994.Product Details of 3034-41-1 This article mentions the following:
4(5)-Substituted imidazoles were alkylated under “neutral” and alk. conditions to give mixtures of isomers in ratios which depended on the reaction conditions, and the nature of the substituent and alkylating agents. In the experiment, the researchers used many compounds, for example, 1-Methyl-4-nitroimidazole (cas: 3034-41-1Product Details of 3034-41-1).
1-Methyl-4-nitroimidazole (cas: 3034-41-1) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Product Details of 3034-41-1
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem