Double head-to-tail direct arylation as a viable strategy towards the synthesis of the aza-analog of dihydrocyclopenta[hi]aceanthrylene – an intriguing antiaromatic heterocycle was written by Firmansyah, Dikhi;Deperasinska, Irena;Vakuliuk, Olena;Banasiewicz, Marzena;Tasior, Mariusz;Makarewicz, Artur;Cyranski, Michal K.;Kozankiewicz, Boleslaw;Gryko, Daniel T.. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2016.Computed Properties of C7H5BrN2 This article mentions the following:
The first case of double head-to-tail direct arylation of aromatic compounds and the unusual photophys. properties of the resulting 2,2a1,5b1,7-tetraazacyclopenta[hi]aceanthrylene are reported. This mol., comprising of two imidazo[1,2-a]pyridine units, is antiarom. due to the changes in the efficiency of π-electron ring current and it belongs to a class of seldom encountered compounds with a dark lowest electronically excited singlet state. In the experiment, the researchers used many compounds, for example, 5-Bromoimidazo[1,2-a]pyridine (cas: 69214-09-1Computed Properties of C7H5BrN2).
5-Bromoimidazo[1,2-a]pyridine (cas: 69214-09-1) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Computed Properties of C7H5BrN2
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem