Nitroimidazoles. Part III. Ionization constants and tautomerism of imidazoles. A reinvestigation was written by Suwinski, Jerzy;Salwinska, Ewa. And the article was included in Polish Journal of Chemistry in 1981.Formula: C4H5N3O This article mentions the following:
Basic and acidic ionization constants of some simple imidazole derivatives were determined spectrophotometrically as well as potentiometrically or taken from the literature. Tautomeric equilibrium constants of the compounds containing an imino H atom were also calculated Methods and results were discussed with regard to the former literature data. In the experiment, the researchers used many compounds, for example, 1H-Imidazole-4-carboxamide (cas: 26832-08-6Formula: C4H5N3O).
1H-Imidazole-4-carboxamide (cas: 26832-08-6) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Formula: C4H5N3O
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem