Kamalakannan, Shanmugasundaram et al. published their research in Journal of Physical Chemistry C in 2019 | CAS: 35487-17-3

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Recommanded Product: 1-Methyl-1H-imidazol-3-ium chloride

Alkyl Methyl Imidazolium-Based Ionic Liquids at the Au(111) Surface: Anions and Alkyl Chain Cations Induced Interfacial Effects was written by Kamalakannan, Shanmugasundaram;Prakash, Muthuramalingam;Al-Mogren, Muneerah Mogren;Chambaud, Gilberte;Hochlaf, Majdi. And the article was included in Journal of Physical Chemistry C in 2019.Recommanded Product: 1-Methyl-1H-imidazol-3-ium chloride This article mentions the following:

The structure, stability, and adsorption mechanism on the Au(111) surface of hydrophilic/hydrophobic ionic liquids (ILs) with various lengths of the alkyl chain group in the cation were studied using 1st-principles approaches including electrostatic potential (ESP), electron d. anal., and dispersion-corrected d. functional theory (DFT-D3) methods. A suitable selection of ILs is considered. Indeed, the authors treat ILs [CnMIm]+[X], where X = Cl, PF6, and TFSA, MIm = methylimidazolium and where the authors varied the alkyl chain (Cn) length for n = 0, 2, 4, 6, 8, and 10. The adsorption energies (Eads‘s) of fluorinated ILs are lower (by âˆ?0%) than those of nonfluorinated ILs. Computations show that the nature of the anion within the ILs and the alkyl chain length play a very important role to alter the interfacial interactions between ILs and Au surface. Indeed, the alkyl groups of the cation affect the cation-anion interaction strength within ILs because of specific modes of adsorption of alkyl chains on the Au(111) surface. Also, structural-induced adsorption effects are observed during the variation of alkyl chain and anions. These are due to the modification of the local properties of the Au surface upon IL adsorption, where the authors identify, in some specific cases, an enhancement of the charge transfers between the ILs and the Au(111) surface through van der Waals and dispersive interactions. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Recommanded Product: 1-Methyl-1H-imidazol-3-ium chloride).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Recommanded Product: 1-Methyl-1H-imidazol-3-ium chloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Hao, Chenzhou et al. published their research in Journal of Medicinal Chemistry in 2018 | CAS: 3034-41-1

1-Methyl-4-nitroimidazole (cas: 3034-41-1) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.HPLC of Formula: 3034-41-1

Structure-Based Design of 6-Chloro-4-aminoquinazoline-2-carboxamide Derivatives as Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors was written by Hao, Chenzhou;Zhao, Fan;Song, Hongyan;Guo, Jing;Li, Xiaodong;Jiang, Xiaolin;Huan, Ran;Song, Shuai;Zhang, Qiaoling;Wang, Ruifeng;Wang, Kai;Pang, Yu;Liu, Tongchao;Lu, Tianqi;Huang, Wanxu;Wang, Jian;Lin, Bin;He, Zhonggui;Li, Haitao;Li, Feng;Zhao, Dongmei;Cheng, Maosheng. And the article was included in Journal of Medicinal Chemistry in 2018.HPLC of Formula: 3034-41-1 This article mentions the following:

Herein, we report the discovery and characterization of a novel class of PAK4 inhibitors with a quinazoline scaffold. Based on the shape and chem. composition of the ATP-binding pocket of PAKs, we chose a 2,4-diaminoquinazoline series of inhibitors as a starting point. Guided by X-ray crystallog. and a structure-based drug design (SBDD) approach, a series of novel 4-aminoquinazoline-2-carboxamide PAK4 inhibitors were designed and synthesized. The inhibitors’ selectivity, therapeutic potency, and pharmaceutical properties were optimized. One of the best compounds, 31 (CZh226), showed remarkable PAK4 selectivity (346-fold vs PAK1) and favorable kinase selectivity profile. Moreover, this compound potently inhibited the migration and invasion of A549 tumor cells by regulating the PAK4-directed downstream signaling pathways in vitro. Taken together, these data support the further development of 31 as a lead compound for PAK4-targeted anticancer drug discovery and as a valuable research probe for the further biol. investigation of group II PAKs. In the experiment, the researchers used many compounds, for example, 1-Methyl-4-nitroimidazole (cas: 3034-41-1HPLC of Formula: 3034-41-1).

1-Methyl-4-nitroimidazole (cas: 3034-41-1) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.HPLC of Formula: 3034-41-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Bianchini, Roberto et al. published their research in ACS Sustainable Chemistry & Engineering in 2015 | CAS: 35487-17-3

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Safety of 1-Methyl-1H-imidazol-3-ium chloride

Ionic Liquids Can Significantly Improve Textile Dyeing: An Innovative Application Assuring Economic and Environmental Benefits was written by Bianchini, Roberto;Cevasco, Giorgio;Chiappe, Cinzia;Pomelli, Christian Silvio;Rodriguez Douton, Maria Jesus. And the article was included in ACS Sustainable Chemistry & Engineering in 2015.Safety of 1-Methyl-1H-imidazol-3-ium chloride This article mentions the following:

Owing to economic reasons, the textile dyeing industry generally employs traditional and absolutely no-eco-friendly processes: very large quantities of water are indeed required together with a large number of added chems. which represent dramatic environmental issues. In order to improve the sustainability of the process, we have investigated the dyeing of wool, polyester, and cotton with disperse Red 13 using ionic liquids as the sole additive. The results obtained in isothermal dyeing at 95 °C show an outstanding effect of the ionic liquid 1-(2-hydroxyethyl)-3-methylimidazolium chloride. This ionic liquid assures efficient dyeing of polyester and wool in open vessels, in the absence of whichever auxiliary agent with total dyebath exhaustion, thus allowing in principle the recycling of the dye bath. The environmental benefits arising from the substitution of a number of usually employed auxiliary agents with only an ionic liquid are highlighted together with the economic ones. This article reports for the first time, to the best of our knowledge, dyeing processes for several kinds of fibers (cotton, wool, and polyester) employing exclusively three components: pure disperse dye, water, and an appropriate ionic liquid In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Safety of 1-Methyl-1H-imidazol-3-ium chloride).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Safety of 1-Methyl-1H-imidazol-3-ium chloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Wang, Haixia et al. published their research in Chemistry – A European Journal in 2018 | CAS: 4887-83-6

7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Quality Control of 7-Methyl-1H-benzo[d]imidazole

Regio- and Enantioselective Allylic Amination of Aliphatic MBH Adducts with N-Heteroaromatics was written by Wang, Haixia;Yu, Lulu;Xie, Mingsheng;Wu, Jiang;Qu, Guirong;Ding, Kuiling;Guo, Haiming. And the article was included in Chemistry – A European Journal in 2018.Quality Control of 7-Methyl-1H-benzo[d]imidazole This article mentions the following:

Palladium-catalyzed regio- and enantioselective allylic amination of aliphatic Morita-Baylis-Hillman (MBH) adducts with N-heteroaromatic nucleophiles (e.g., benzimidazole, 4,5-diphenylimidazole, benzotriazole, and purines) was achieved by using a spiroketal-based diphosphine (SKP) ligand, and afforded a range of chiral, branched N-allyl products with high selectivity. In the experiment, the researchers used many compounds, for example, 7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6Quality Control of 7-Methyl-1H-benzo[d]imidazole).

7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Quality Control of 7-Methyl-1H-benzo[d]imidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Bayly, Alison A. et al. published their research in Proceedings of the National Academy of Sciences of the United States of America in 2020 | CAS: 1632-83-3

1-Methylbenzimidazole (cas: 1632-83-3) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Electric Literature of C8H8N2

High-throughput photocapture approach for reaction discovery was written by Bayly, Alison A.;McDonald, Benjamin R.;Mrksich, Milan;Scheidt, Karl A.. And the article was included in Proceedings of the National Academy of Sciences of the United States of America in 2020.Electric Literature of C8H8N2 This article mentions the following:

Modern organic reaction discovery and development relies on the rapid assessment of large arrays of hypothesis-driven experiments The time-intensive nature of reaction anal. presents the greatest practical barrier for the execution of this iterative process that underpins the development of new bioactive agents. Toward addressing this critical bottleneck, the authors report herein a high-throughput anal. (HTA) method of reaction mixtures by photocapture on a 384-spot diazirine-terminated self-assembled monolayer, and self-assembled monolayers for matrix-assisted laser desorption/ionization mass spectrometry (SAMDI-MS) anal. This anal. platform has been applied to the identification of a single-electron-promoted reductive coupling of acyl azolium species. In the experiment, the researchers used many compounds, for example, 1-Methylbenzimidazole (cas: 1632-83-3Electric Literature of C8H8N2).

1-Methylbenzimidazole (cas: 1632-83-3) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Electric Literature of C8H8N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Althanoon, Zeina A. et al. published their research in Pharmacognosy Journal in 2022 | CAS: 145040-37-5

1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate (cas: 145040-37-5) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Electric Literature of C33H34N6O6

Comparative effects of amlodipine and candesartan on blood pressure and metabolic profile in non-diabetic hypertensive patients was written by Althanoon, Zeina A.;Thanoon, Imad AJ. And the article was included in Pharmacognosy Journal in 2022.Electric Literature of C33H34N6O6 This article mentions the following:

Introduction: The present study aimed to compare the effects of the angiotensin II receptor blocker candesartan and the calcium channel blocker amlodipine on blood pressure and metabolic profile in non-diabetic hypertensive patients. Methods: The study involved non-diabetic patients with mild to moderate hypertension. They were randomly assigned to receive candesartan or amlodipine for 24 wk, parameters were evaluated at baseline and after 12 wk and 24 wk for each patient group. Results: Candesartan and amlodipine both reduced blood pressure and the HOMA-IR index significantly (P < 0.05, 24 wk vs. baseline). Candesartan was more effective than amlodipine in lowering blood pressure and HOMA-IR, although the difference was not significant statistically. Conclusion: Both candesartan and amlodipine are extremely effective at reducing blood pressure in moderate hypertension patients. Candesartan cilexetil has a major benefit in terms of tolerability, as it reduces the risk of developing metabolic dysregulation. In the experiment, the researchers used many compounds, for example, 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate (cas: 145040-37-5Electric Literature of C33H34N6O6).

1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate (cas: 145040-37-5) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Electric Literature of C33H34N6O6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Korshak, V. V. et al. published their research in Vysokomolekulyarnye Soedineniya, Seriya B: Kratkie Soobshcheniya in 1967 | CAS: 4887-83-6

7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Product Details of 4887-83-6

Polybenzimidazoles based on methylated benzene tetraamines was written by Korshak, V. V.;Teplyakov, M. M.;Fedorova, R. D.. And the article was included in Vysokomolekulyarnye Soedineniya, Seriya B: Kratkie Soobshcheniya in 1967.Product Details of 4887-83-6 This article mentions the following:

3,3′-Diaminotolidine (I) and 2,3′,4,4′-tetraaminoditolylmethane (II) were synthesized and were used to prepare polybenzimidazoles with di-Ph isophthalate (III), di-Ph terephthalate (IV), di-Ph adipate (V), and di-Ph sebacate (VI). The polybenzimidazoles obtained had the following properties (amine, ester, intrinsic viscosity in HCO2H, and decomposition temperature given): I, V, 0.76, -; I, VI, 0.80, -; I, III, 0.40, 490°; I, IV, 0.42, 500°; II, III-IV, 0.51, 490°; II, III, 0.64, -; II, III, 0.47, 400°; II, IV, 0.41, 450°. In the experiment, the researchers used many compounds, for example, 7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6Product Details of 4887-83-6).

7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Product Details of 4887-83-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Zaky, M. T. et al. published their research in Journal of Molecular Liquids in 2019 | CAS: 21252-69-7

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Synthetic Route of C11H20N2

Synthesis of new ionic liquids based on dicationic imidazolium and their anti-corrosion performances was written by Zaky, M. T.;Nessim, M. I.;Deyab, M. A.. And the article was included in Journal of Molecular Liquids in 2019.Synthetic Route of C11H20N2 This article mentions the following:

Ionic liquids with high environmental value and adsorption properties are a requirement for the new trend for corrosion inhibitors. Here, we synthesis three new ionic liquids based on dicationic imidazolium (IL1, IL2 and IL3) to produce green inhibitors for stainless steel corrosion in acidic environment. The anionic portion of all prepared ionic liquids is BF-4. New ionic liquids were recognized by means of element inspection, FT-IR, TGA and 1H NMR spectroscopy. All prepared ionic liquids work as good corrosion inhibitors. Where their efficiencies are 91.5%, 98.4% and 83.3% for IL1, IL2 and IL3, resp. at 100 ppm. The counter portion of ILs (BF-4) has a great role in the adsorption process. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Synthetic Route of C11H20N2).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Synthetic Route of C11H20N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Kortagere, Sandhya et al. published their research in Journal of Chemical Information and Modeling in 2014 | CAS: 5496-35-5

4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoic acid (cas: 5496-35-5) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Recommanded Product: 5496-35-5

Structure-Activity Relationships of a Novel Capsid Targeted Inhibitor of HIV-1 Replication was written by Kortagere, Sandhya;Xu, Jimmy P.;Mankowski, Marie K.;Ptak, Roger G.;Cocklin, Simon. And the article was included in Journal of Chemical Information and Modeling in 2014.Recommanded Product: 5496-35-5 This article mentions the following:

Despite the considerable successes of highly active antiretroviral therapy (HAART) for the treatment of HIV/AIDS, cumulative drug toxicities and the development of multidrug-resistant virus necessitate the search for new classes of antiretroviral agents with novel modes of action. The HIV-1 capsid (CA) protein has been structurally and functionally characterized as a druggable target. We have recently designed a novel small mol. inhibitor I-XW-053 using the hybrid structure based method to block the interface between CA N-terminal domains (NTD-NTD interface) with micromolar affinity. In an effort to optimize and improve the efficacy of I-XW-053, we have developed the structure activity relationship of I-XW-053 compound series using ligand efficiency methods. Fifty-six analogs of I-XW-053 were designed that could be subclassified into four different core domains based on their ligand efficiency values computed as the ratio of binding efficiency (BEI) and surface efficiency (SEI) indexes. Compound 34 belonging to subcore-3 showed an 11-fold improvement over I-XW-053 in blocking HIV-1 replication in primary human peripheral blood mononuclear cells (PBMCs). Surface plasmon resonance experiments confirmed the binding of compound 34 to purified HIV-1 CA protein. Mol. docking studies on compound 34 and I-XW-053 to HIV-1 CA protein suggested that they both bind to NTD-NTD interface region but with different binding modes, which was further validated using site-directed mutagenesis studies. In the experiment, the researchers used many compounds, for example, 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoic acid (cas: 5496-35-5Recommanded Product: 5496-35-5).

4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoic acid (cas: 5496-35-5) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Recommanded Product: 5496-35-5

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Zhang, Zhaofei et al. published their research in Science Bulletin in 2022 | CAS: 1632-83-3

1-Methylbenzimidazole (cas: 1632-83-3) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Safety of 1-Methylbenzimidazole

Semi-heterogeneous photo-Cu-dual-catalytic cross-coupling reactions using polymeric carbon nitrides was written by Zhang, Zhaofei;Xu, Yangsen;Zhang, Qitao;Fang, Shaofan;Sun, Hongli;Ou, Wei;Su, Chenliang. And the article was included in Science Bulletin in 2022.Safety of 1-Methylbenzimidazole This article mentions the following:

A merger of copper catalysis and semiconductor photocatalysis using polymeric carbon nitride (PCN) for multi-type cross-coupling reactions was developed. This dual catalytic system enables mild C-H arylation, chalcogenation, and C-N cross-coupling reactions under visible light irradiation with a broad substrate scope. Good to excellent yields were obtained with appreciable site selectivity and functional group tolerance. Metal-free and low-cost PCN photocatalyst can easily be recovered and reused several times. In the experiment, the researchers used many compounds, for example, 1-Methylbenzimidazole (cas: 1632-83-3Safety of 1-Methylbenzimidazole).

1-Methylbenzimidazole (cas: 1632-83-3) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Safety of 1-Methylbenzimidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem