Month: January 2023

Poly(ionic liquid)-Coated Meshes with Opposite Wettability for Continuous Oil/Water Separation was written by Deng, Xi;Zhang, Jingshun;Zhang, Liren;Cheng, Guiren;Chen, Bihua;Zhang, Yongya;Gao, Guohua. And the article was included in Industrial & Engineering Chemistry Research in 2020.Application of 915358-85-9 This article mentions the following:

A series of oil/water separation membranes with tunable surface wettability based on poly(ionic liquid)s (PILs) were prepared via a facile one-step photopolymerization of N-vinylimidazolium ionic liquids and divinylbenzene on meshes. The wettability of PIL-based membranes (PILMs) was adjusted by the structures of PILs, specifically the alkyl chain length of imidazolium (Bu and octyl) and anion species (acrylic anion, Br^–, and PF₆^–). Tunability of wettability resulted in the hydrophilic or hydrophobic property of PILMs. The hydrophilic poly(1-vinyl-3-butylimidazolium acrylate)-based membrane (PILM-1) transported water and intercepted oil, while the hydrophobic poly(1-vinyl-3-octylimidazolium hexafluorophosphate)-based membrane (PILM-5) removed oil and rejected water. The two membranes with opposite wettability showed excellent oil/water separation efficiency (above 99%) in batch processes. Continuous oil/water separation was also achieved by assembling PILM-1 and PILM-5 on the fabricated devices. A T-type device could sep. various oil/water mixtures continuously, and a tank-type device could sep. dispersed oil/water mixtures, with a handling capacity of 46 L within 12 h. In the experiment, the researchers used many compounds, for example, 1-Butyl-3-vinyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 915358-85-9Application of 915358-85-9).

1-Butyl-3-vinyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 915358-85-9) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Application of 915358-85-9

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Selective CO₂ Reduction to Ethylene Using Imidazolium-Functionalized Copper was written by Cheng, Banggui;Du, Jiehao;Yuan, Huiqing;Tao, Yuan;Chen, Ya;Lei, Jingxiang;Han, Zhiji. And the article was included in ACS Applied Materials & Interfaces in 2022.Reference of 21252-69-7 This article mentions the following:

Electrochem. CO₂ reduction is a promising approach to obtain sustainable chems. in energy conversion. Improving the selectivity of CO₂ reduction toward a particular C₂ product such as ethylene remains a significant challenge. Herein, we report a series of imidazolium hexafluorophosphate compounds as surface modifiers for planar Cu foils to boost the Faradaic efficiency (FE) of ethylene from 5 to 73%, which is among the highest reported using polycrystalline Cu. The modified electrodes are convenient to prepare The structure-function study demonstrates that varying the alkyl or aromatic substituents on the imidazolium nitrogen atoms has significant effects on the morphol. of the deposited films and the product selectivity of CO₂ reduction Exptl. FE_Câ‰?, FE_C2H4, ln(FE_Câ‰?/FE_CH4), and ln(FE_C2H4/FE_C2H5OH) values show generally linear relationships with FE_H2 while using different imidazolium modifiers, suggesting that factors governing proton reduction may also be directly related to both overall C_â‰? generation and ethylene selectivity. This work presents an effective and practical way in tailoring the active sites of metallic surface for selective CO₂ reduction In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Reference of 21252-69-7).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Reference of 21252-69-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Leaching separation of taurine and sodium sulfate solid mixture using ionic liquids was written by Gu, Yanlong;Shi, Feng;Yang, Hongzhou;Deng, Youquan. And the article was included in Separation and Purification Technology in 2004.HPLC of Formula: 79917-89-8 This article mentions the following:

The solubilities of taurine [2-aminoethanesulfonic acid (H₂NCH₂CH₂SO₃H)] and sodium sulfate in a series of room temperature ionic liquids were examined, and a novel and greener separation method combined with chlorinated dialkylimidazolium ionic liquid as leaching reagent and organic solvent as precipitating reagent was developed. Using such a process, selective separation of taurine from a solid mixture containing a large amount of sodium sulfate could be realized with 67-98.5% of single separation yield. Recycling of ionic liquid and organic solvent used in this separation process is possible. In the experiment, the researchers used many compounds, for example, 1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8HPLC of Formula: 79917-89-8).

1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.HPLC of Formula: 79917-89-8

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Novel synthetic methods for N-cyano-1H-imidazole-4-carboxamides and their fungicidal activity was written by Yang, Wen-Chao;Li, Jing;Li, Jun;Chen, Qiong;Yang, Guang-Fu. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2012.Related Products of 26832-08-6 This article mentions the following:

A novel synthetic method for N-cyanoimidazolecarboxamides has been developed with advantages of mild reaction conditions, simpler procedure, and easy reactant-product isolation compared with the existing methods. Thus, a one-step or two-step alkylation of 8-methylimidazo[1,5-d][1,2,4]triazin-1-(2H)-one gave N-cyanocarboxamides. Using this novel method, 16 new N-cyano-1H-imidazole-4-carboxamide derivatives were synthesized and their structures were characterized by spectrum anal. Further antifungal activity study showed that most of the newly synthesized compounds have good antifungal activity selectively against Rhizoctonia solani among the six fungi tested. Particularly, compound I was identified as the most promising candidate with an EC₅₀ of 2.63 μg/mL against R. solani. In the experiment, the researchers used many compounds, for example, 1H-Imidazole-4-carboxamide (cas: 26832-08-6Related Products of 26832-08-6).

1H-Imidazole-4-carboxamide (cas: 26832-08-6) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Related Products of 26832-08-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Accuracy of Algorithm to Non-Invasively Predict Core Body Temperature Using the Kenzen Wearable Device. was written by Moyen, Nicole E;Bapat, Rohit C;Tan, Beverly;Hunt, Lindsey A;Jay, Ollie;Mündel, Toby. And the article was included in International journal of environmental research and public health in 2021.Recommanded Product: 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate This article mentions the following:

With climate change increasing global temperatures, more workers are exposed to hotter ambient temperatures that exacerbate risk for heat injury and illness. Continuously monitoring core body temperature (T_C) can help workers avoid reaching unsafe T_C. However, continuous T_C measurements are currently cost-prohibitive or invasive for daily use. Here, we show that Kenzen’s wearable device can accurately predict T_C compared to gold standard T_C measurements (rectal probe or gastrointestinal pill). Data from four different studies (n = 52 trials; 27 unique subjects; >4000 min data) were used to develop and validate Kenzen’s machine learning T_C algorithm, which uses subject’s real-time physiological data combined with baseline anthropometric data. We show Kenzen’s T_C algorithm meets pre-established accuracy criteria compared to gold standard T_C: mean absolute error = 0.25 °C, root mean squared error = 0.30 °C, Pearson r correlation = 0.94, standard error of the measurement = 0.18 °C, and mean bias = 0.07 °C. Overall, the Kenzen T_C algorithm is accurate for a wide range of T_C, environmental temperatures (13-43 °C), light to vigorous heart rate zones, and both biological sexes. To our knowledge, this is the first study demonstrating a wearable device can accurately predict T_C in real-time, thus offering workers protection from heat injuries and illnesses. In the experiment, the researchers used many compounds, for example, 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate (cas: 145040-37-5Recommanded Product: 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate).

1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate (cas: 145040-37-5) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Recommanded Product: 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Structure of Alkylimidazolium-Based Ionic Liquids at the Interface with Vacuum and Water-A Molecular Dynamics Study was written by Konieczny, Jan K.;Szefczyk, Borys. And the article was included in Journal of Physical Chemistry B in 2015.Electric Literature of C18H31F6N3O4S2 This article mentions the following:

Ionic liquid (IL) interfaces with vacuum and water are studied by means of classical mol. dynamics simulations. Five ILs are compared: [C₂mim][TfO], [C₁₂mim][TfO], [C₂mim][NTf₂], [C₈mim][NTf₂] and [C₁₂mim][NTf₂], where [C₂mim], [C₈mim] and [C₁₂mim] stand for 1-ethyl-, 1-octyl- and 1-dodecyl-3-methylimidazolium cation. Phys. properties – d., thermal expansion coefficient, compressibility, surface tension, heat of vaporization, self-diffusion coefficient, elec. conductivity and viscosity – are calculated and validated against exptl. values. The structure of the interfaces is compared in terms of the orientation of the mols. and segregation into layers. It is observed that ILs with short alkyl chains orient at the surface; however, there is no single preferred orientation. ILs with longer chains, on the other hand, orient with alkyl chains protruding into the vacuum at the IL/vacuum interface and into the bulk IL, at the IL/water interface. Anions and water mols. tend to associate with polar imidazolium groups. In the experiment, the researchers used many compounds, for example, 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5Electric Literature of C18H31F6N3O4S2).

3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Electric Literature of C18H31F6N3O4S2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Discovery of unsymmetrical aromatic disulfides as novel inhibitors of SARS-CoV main protease: Chemical synthesis, biological evaluation, molecular docking and 3D-QSAR study was written by Wang, Li;Bao, Bo-Bo;Song, Guo-Qing;Chen, Cheng;Zhang, Xu-Meng;Lu, Wei;Wang, Zefang;Cai, Yan;Li, Shuang;Fu, Sheng;Song, Fu-Hang;Yang, Haitao;Wang, Jian-Guo. And the article was included in European Journal of Medicinal Chemistry in 2017.Quality Control of Ethyl 2-mercapto-1H-imidazole-4-carboxylate This article mentions the following:

The worldwide outbreak of severe acute respiratory syndrome (SARS) in 2003 had caused a high rate of mortality. Main protease (M^pro) of SARS-associated coronavirus (SARS-CoV) is an important target to discover pharmaceutical compounds for the therapy of this life-threatening disease. During the course of screening new anti-SARS agents, a series of unsym. aromatic disulfides inhibited SARS-CoV M^pro significantly for the first time have been identified. Novel unsym. aromatic disulfides R¹SSR² [R¹ = 1,3-thiazol-2-ylsulfanyl, 1,3,4-oxadiazol-2-ylsulfanyl, pyrimidin-2-ylsulfanyl, etc.; R² = phenylsulfanyl, 4-bromophenylsulfanyl, [2-(methoxycarbonyl)phenyl]sulfanyl, etc.] were synthesized chem. and their biol. activities were evaluated in vitro against SARS-CoV Mpro. These novel compounds displayed excellent IC₅₀ data in the range of 0.516-5.954 μM. Preliminary studies indicated that these disulfides are reversible and competitive inhibitors. A possible binding mode was generated via mol. docking simulation and a comparative field anal. (CoMFA) model was constructed to understand the structure-activity relationships. The present research therefore has provided some meaningful guidance to design and identify anti-SARS drugs with totally new chem. structures. In the experiment, the researchers used many compounds, for example, Ethyl 2-mercapto-1H-imidazole-4-carboxylate (cas: 64038-64-8Quality Control of Ethyl 2-mercapto-1H-imidazole-4-carboxylate).

Ethyl 2-mercapto-1H-imidazole-4-carboxylate (cas: 64038-64-8) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Quality Control of Ethyl 2-mercapto-1H-imidazole-4-carboxylate

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Preparatory study for the synthesis of the starfish alkaloid imbricatine. Syntheses of 5-arylthio-3-methyl-L-histidines was written by Ohba, Masashi;Mukaihira, Takafumi;Fujii, Tozo. And the article was included in Chemical & Pharmaceutical Bulletin in 1994.SDS of cas: 25676-75-9 This article mentions the following:

Chiral syntheses of 3-methyl-5-(arylthio)-L-histidines I (R = Ph, 1-naphthyl), selected as models for the asteroid alkaloid imbricatine, have been accomplished through a 10-step route starting from 4(5)-bromoimidazole (II). The key steps involved were methylation of II, hydroxymethylation of 4-bromo-1-methyl-1H-imidazole, replacement of the 4-bromo group by an arylthio group, and introduction of a chiral α-amino acid moiety into the chlorides III by the bislactim ether method. The synthesis of 4-(4-methoxybenzyl)thio analog III (R = 4-MeOC₆H₄CH₂), carried out in a similar manner, concluded formal syntheses of ovothiols A and C. In the experiment, the researchers used many compounds, for example, 4-Bromo-1-methylimidazole (cas: 25676-75-9SDS of cas: 25676-75-9).

4-Bromo-1-methylimidazole (cas: 25676-75-9) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. SDS of cas: 25676-75-9

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Self-Supporting, Hydrophobic, Ionic Liquid-Based Reference Electrodes Prepared by Polymerization-Induced Microphase Separation was written by Chopade, Sujay A.;Anderson, Evan L.;Schmidt, Peter W.;Lodge, Timothy P.;Hillmyer, Marc A.;Buhlmann, Philippe. And the article was included in ACS Sensors in 2017.SDS of cas: 404001-48-5 This article mentions the following:

Interfaces of ionic liquids and aqueous solutions exhibit stable elec. potentials over a wide range of aqueous electrolyte concentrations This makes ionic liquids suitable as bridge materials that sep. in electroanal. measurements the reference electrode from samples with low and/or unknown ionic strengths. However, methods for the preparation of ionic liquid-based reference electrodes were not explored widely. The authors have designed a convenient and reliable synthesis of ionic liquid-based reference electrodes by polymerization-induced microphase separation This technique allows for a facile, single-pot synthesis of ready-to-use reference electrodes that incorporate ion conducting nanochannels filled with either 1-octyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide or 1-dodecyl-3-methylimidazolium bis(trifluoromethyl sulfonyl)imide as ionic liquid, supported by a mech. robust cross-linked polystyrene phase. This synthesis procedure allows for the straightforward design of various reference electrode geometries. These reference electrodes exhibit a low resistance as well as good reference potential stability and reproducibility when immersed into aqueous solutions varying from deionized, purified H₂O to 100 mM KCl, while requiring no correction for liquid junction potentials. In the experiment, the researchers used many compounds, for example, 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5SDS of cas: 404001-48-5).

3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.SDS of cas: 404001-48-5

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Significant effect of 5,10,15,20-meso-tetraarylporphyrinatoiron(III) chloride/triflate and acidic/neutral/basic imidazolium ionic liquids in catalytic oxidation of phenols was written by Ahmad, Sohail;Gautam, Renu;Singhal, Anchal;Chauhan, S. M. S.. And the article was included in Journal of Molecular Liquids in 2018.Category: imidazoles-derivatives This article mentions the following:

The influence of acidic, neutral and basic ionic liquids and their binary mixture with dichloromethane on the reactivity of iron(III) porphyrins was investigated during oxidation of phenols with hydrogen peroxide catalyzed by 5,10,15,20-tetraarylporphyrinatoiron(III) chloride and 5,10,15,20-tetraarylporphyrinatoiron(III) triflate. The generation of different intermediates of iron(III) porphyrin in different ILs was studied through viscosity, d., UV-Vis and ¹H NMR spectroscopy. The heterolytic cleavage efficiency of (TAP)Fe^III-OOH and formation of quinone using iron(III)porphyrin (TAP)Fe^IIICl with Cl atom as an axial ligand, is influenced by the structure of imidazolium moiety and the counter-anion following the order [(CH₂)₄SO₃HMIm]CF₃COO > [Hmim]CF₃COO > [bmim]TFA >>>> negligible amount in [bmim]CF₃SO₃, [Hmim]CF₃SO₃, [bmim]BF₄, [bmim]PF₆ and [bmim]Cl. On the other hand, the heterolytic cleavage efficiency of (TAP)Fe^III-OOH with iron(III)porphyrin (TAP)Fe^IIICF₃SO₃ with triflate as an axial ligand, was found in the following order [(CH₂)₄SO₃HMIm]CF₃SO₃ > [Hmim]CF₃SO₃ > [(CH₂)₄SO₃HMIm]CF₃COO > [Hmim]CF₃COO > [bmim] CF₃COO > [bmim]PF₆ â‰?[bmim]BF₄ â‰?[bmim]CF₃SO₃, while epoxidation and polymerization were mainly observed in basic and neutral ILs. The reactive intermediates formed by the reaction of monooxygen donors with (TAP)Fe^IIICl varied with ILs, as (TAP)^+·Fe^IV = O intermediate was dominated in acidic ILs, while (TAP)Fe^IV = O was formed in neutral ILs and (TAP)Fe^III-OO^– was formed in basic ILs. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Category: imidazoles-derivatives).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Category: imidazoles-derivatives

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem