Month: January 2023

Production of alkylated gasoline using ionic liquids and immobilized ionic liquids was written by Kumar, Prashant;Vermeiren, Walter;Dath, Jean-Pierre;Hoelderich, Wolfgang F.. And the article was included in Applied Catalysis, A: General in 2006.Computed Properties of C7H13ClN2 This article mentions the following:

Ionic liquids (ILs) and silica-immobilized ionic liquids were used as acid catalysts for the liquid phase alkylation of raffinate II (the C₄-cut of the steam cracker offgases after removal of butadienes, isobutene, and C₃-hydrocarbons) and isobutane. The influences of reactant concentration (molar ratio of i-C₄/C₄-alkenes), time, temperature and acid strength of the ionic liquids were studied. Using a step-up design under batch conditions with a very dilute mixture of isobutane and alkene, the conversion for a variety of ionic liquids followed a pattern based on acid strength of the catalyst. Imidazolium-based ILs were superior to phosphonium-based ILs. Novel Lewis-Acid Catalysts II (NLAC II, immobilization by grafting on siliceous MCM 41 or on silica FK 700) were better than other solid acid catalysts tested, such as SAC 13, zeolite H-Beta (Si/Al = 14:1) and NLAC I (impregnation of ILs on silica FK 700). Possible leaching of the ionic liquid from the catalyst surface was followed by ICP measurements of the catalyst after reaction and of the reaction mixture In the experiment, the researchers used many compounds, for example, 1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8Computed Properties of C7H13ClN2).

1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Computed Properties of C7H13ClN2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

New amphiphilic imidazolium/benzimidazolium calix[4]arene derivatives: synthesis, aggregation behavior and decoration of DPPC vesicles for Suzuki coupling in aqueous media was written by Burilov, Vladimir;Garipova, Ramilya;Sultanova, Elsa;Mironova, Diana;Grigoryev, Ilya;Solovieva, Svetlana;Antipin, Igor. And the article was included in Nanomaterials in 2020.Safety of 1-Methylbenzimidazole This article mentions the following:

In this study, new types of amphiphilic calix[4]arene derivatives bearing N-alkyl/aryl imidazolium/benzimidazolium fragments, e.g., 11,23-bis[(3-methyl-1H-imidazolium-1-yl)methyl]-25,27-dihydroxy-26,28-dibutoxycalix[4]arene dichloride were designed and synthesized by two step transformation: Regioselective Blanc chloromethylation of distal-di-O-Bu calix[4]arene and subsequent interaction with N-Substituted imidazole/benzimidazole. Critical aggregation concentration (CAC) values were estimated using pyrene fluorescent probe. Obtained macrocycles were found to form submicron particles with electrokinetic potential +44-+57 mV in aqueous solution For the first time it was found that amphiphilic calixarene causes the fast transformation of 1,2-dipalmitoyl-sn-glycero-3- phosphocholine (DPPC) multilamellar vesicles into unilamellar ones and leads to the ordering of the lipid in membranes at the molar calixarene/DPPC ratio more than 0.07. In situ complexes of calixarene aggregates with Pd(OAc)₂ were found to be active in Suzuki-Miyaura coupling of 1-bromo-4- nitrobenzene with phenylboronic acid in water. It was shown that bulky N-substituents of heterocycle decrease the catalytic activity of the aggregates. These result can be assigned to the inhibition effect of Pd(II) complex in situ formation by bulky substituents located on the aggregate surface. Embedding of the most active palladium N-heterocyclic carbene (NHC) complex with methylimidazolium headgroups into DPPC vesicles enhances its catalytic activity in Suzuki-Miyaura coupling. In the experiment, the researchers used many compounds, for example, 1-Methylbenzimidazole (cas: 1632-83-3Safety of 1-Methylbenzimidazole).

1-Methylbenzimidazole (cas: 1632-83-3) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Safety of 1-Methylbenzimidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Biorefinery potential of sustainable municipal wastewater treatment using fast-growing willow was written by Sas, E.;Hennequin, L. M.;Fremont, A.;Jerbi, A.;Legault, N.;Lamontagne, J.;Fagoaga, N.;Sarrazin, M.;Hallett, J. P.;Fennell, P. S.;Barnabe, S.;Labrecque, M.;Brereton, N. J. B.;Pitre, F. E.. And the article was included in Science of the Total Environment in 2021.Quality Control of 1-Methyl-1H-imidazol-3-ium chloride This article mentions the following:

The use of willow plantations can be a sustainable approach for treating primary municipal wastewater, potentially reducing both the environmental and economic burdens associated with conventional treatment. However, the impact of wastewater irrigation upon the willow biorefinery potential has not yet been established. To investigate this effect, three-year-old field grown willows were harvested from plots kept as either controls or irrigated with primary municipal wastewater effluent at 29.5 million L ha^-1 yr^-1. Biomass compositional anal., ionic liquid pretreatment and enzymic saccharification were assessed and differential abundance of persistent extractable phytochems. was evaluated using untargeted metabolite profiling. Glucan significantly increased by 8% in wastewater treated trees, arabinose and galactose were significantly decreased by 8 and 29%, resp., while xylose, mannose and lignin content were unaltered. Ionic liquid pretreatment and enzymic saccharification efficiencies did not vary significantly, releasing >95% of the cell wall glucose and recovering 35% of the lignin. From a total of 213 phytochem. features, 83 were significantly depleted and 14 were significantly enriched due to wastewater irrigation, including flavonoids and lignan derivatives Considered alongside increased biomass yield from wastewater irrigation (+200%), lignocellulosic bioenergy yields increased to 8.87 t glucose ha^-1 yr^-1 and 1.89 t ha-1 yr-1ha^-1 yr^-1 recovered lignin, while net extractives yields increased to 1.48 t ha^-1 yr^-1, including phytochems. of interest. The maintenance of glucose accessibility after low-cost ionic liquid pretreatment is promising evidence that sustainable lignocellulose bioenergy production can complement wastewater treatment. Untargeted metabolite assessment revealed some of the phytochem. toolkit employed by wastewater irrigated willows, including accumulation of flooding and salinity tolerance associated flavonoids glabraoside A and glabrene. The extractable phytochems. underpin a novel high biomass phenotype in willow and, alongside lignocellulosic yields, could help enhance the economic feasibility of this clean wastewater treatment biotechnol. through integration with sustainable biorefinery. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Quality Control of 1-Methyl-1H-imidazol-3-ium chloride).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Quality Control of 1-Methyl-1H-imidazol-3-ium chloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Long Chain Alkylated Ionic Liquids as Pour Point Depressant and Rheology Improver for Crude Oil was written by Hazrati, N.;Abdouss, M.;Miran-Beigi, A. A.;Pasban, A. A.. And the article was included in Petroleum Chemistry in 2021.Electric Literature of C18H31F6N3O4S2 This article mentions the following:

Abstract: Cold flow properties of Iranian crude oil have been investigated by two different imidazolium ionic liquids including 1-dodecyl-3-methylimidazolium reduce the pour point up to bis(trifluoromethanesulfonyl) imide ([C₁₂min][NTf₂]) and 1-tetradecyl-3-methylimidazolium bis(trifluoromethanesulfonyl) imide ([C₁₄min][NTf₂]). ([C₁₄min][NTf₂]) showed high ability to 12°C optimal performance by addition of 2000 ppm. Wax crystallization behavior of untreated and treated crude oil was monitored using differential scanning calorimetry (DSC) and the polarized optical microscopy (POM). Results from DSC and POM revealed that the presence of both ILs changes the process of crystallization and extends wax precipitation time. Furthermore, rheol. behavior of the crude oil was improved and viscosity was decreased by 73% at 23.5°C and 87% at 15°C by addition of [C₁₄mim][NTf₂]. In the experiment, the researchers used many compounds, for example, 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5Electric Literature of C18H31F6N3O4S2).

3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Electric Literature of C18H31F6N3O4S2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Preparation of AgCl with enhanced photocatalytic activity using ionic liquid as chlorine source was written by Li, Zhao;Huang, Jiao;Zhong, Junbo;Li, Jianzhang. And the article was included in Applied Physics A: Materials Science & Processing in 2020.Recommanded Product: 1-Methyl-3-propylimidazolium Chloride This article mentions the following:

Abstract: In this study, Ag/AgCl photocatalysts were prepared by using chloride ionic liquid (IL) as a chlorine source. The structure, composition, morphol., light response ability and surface properties of IL-AgCl were characterized by X-ray diffraction, scanning electron microscope, XPS, Raman spectroscopy, UV-Vis diffuse reflection spectra, sp. surface area and surface photovoltage spectrum. The photocatalytic activity of the samples was investigated by measuring the residual concentration of rhodamine B used as a simulated pollutant. The exptl. results show that the ionic liquid can promote the stability of AgCl, furthermore, all the IL-AgCl photocatalysts have a higher separation rate of photogenerated charge pairs than the reference AgCl. The surface properties and photocatalytic activity of AgCl prepared tightly relate to the type of IL used, among all the AgCl prepared, AgCl prepared by 1-carboxyethyl-3-methyl-imidazolium chloride has the best catalytic activity. In the experiment, the researchers used many compounds, for example, 1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8Recommanded Product: 1-Methyl-3-propylimidazolium Chloride).

1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Recommanded Product: 1-Methyl-3-propylimidazolium Chloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Ionic liquid-mediated transcutaneous protein delivery with solid-in-oil nanodispersions was written by Araki, Shota;Wakabayashi, Rie;Moniruzzaman, Muhammad;Kamiya, Noriho;Goto, Masahiro. And the article was included in MedChemComm in 2015.Computed Properties of C18H31F6N3O4S2 This article mentions the following:

As a potentially safe and non-invasive vaccination method, transcutaneous immunization represents an attractive alternative to conventional vaccine delivery by injection. However, the development of transcutaneous immunization has remained a challenge for a large number of hydrophilic macromols. including protein and peptide antigens. We report a novel ionic liquid (IL)-mediated transcutaneous vaccine formulation consisting of a solid-in-oil (S/O) nanodispersion of antigen coated with pharmaceutically accepted surfactants dispersed in IL-containing oil. The introduction of the IL [C₁₂mim][Tf₂N] (1-dodecyl-3-Me imidazolium bis(trifluoromethyl sulfonyl) amide) as a penetration enhancer in the formulation significantly enhanced the skin permeability of ovalbumin (OVA), a model antigen. It was also found that the IL-mediated S/O nanodispersion obtained high levels of OVA-specific serum IgG compared with both S/O nanodispersions without IL and PBS control. These findings clearly indicate that ILs – which are potentially attractive “green” and “designer” solvents – could serve as potential skin penetration enhancers in transcutaneous vaccination for hydrophilic macromols. In the experiment, the researchers used many compounds, for example, 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5Computed Properties of C18H31F6N3O4S2).

3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Computed Properties of C18H31F6N3O4S2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Cooperative Catalytic Activation of Si-H Bonds: CO₂-Based Synthesis of Formamides from Amines and Hydrosilanes under Mild Conditions was written by Luo, Rongchang;Lin, Xiaowei;Chen, Yaju;Zhang, Wuying;Zhou, Xiantai;Ji, Hongbing. And the article was included in ChemSusChem in 2017.Quality Control of 1-Octyl-1H-imidazole This article mentions the following:

A simple cooperative catalytic system was successfully developed for the solvent-free N-formylation of amines such as morpholine, 2,3-dihydro-1H-indole, 2,6-dimethylpiperazine, etc. with CO₂ and hydrosilanes under ambient conditions and composed of a Zn(salen) catalyst and quaternary ammonium salt. These com. available binary components activated the Si-H bonds effectively, owing to the intermol. synergistic effect between Lewis base and transition metal center (LB-TM), and subsequently facilitated the insertion of CO₂ to form the active silyl formats, thereby leading to excellent catalytic performance at a low catalyst loading. Furthermore, the bifunctional Zn(salen) complexes, with two imidazolium-based ionic-liquid (IL) units at the 3,3′-position of salen ligand, acted as intramolecularly cooperative catalysts, and the solvent-regulated separation resulted in facile catalyst recycling and reuse. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Quality Control of 1-Octyl-1H-imidazole).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Quality Control of 1-Octyl-1H-imidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Proteolytic enzymes. Models for electrophilic assistance by NH in acylation was written by Williams, A.;Salvadori, G.. And the article was included in Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999) in 1972.Category: imidazoles-derivatives This article mentions the following:

The effect of increasing dioxane content of the medium was used to examine the possibility of intramol. electrophilic assistance by NH in alk. hydrolysis of the Me esters of 2-acetamidobenzoic, 2-pyrrolecarboxylic (I), and benzimidazole-4(7)-carboxylic (II) acids. Significant rate constant enhancement was observed for positional isomers where participation was possible; enhancements increased rapidly with increasing dioxane concentration, thus agreeing with a built-in solvation by NH of the incipient alkoxide ion (derived from the carbonyl O) of the transition state. I and II had maximum in their rate enhancements as the dioxane content increased. The NH to alkoxide bond distance in I and II is larger than normally found for direct H-bonding and the maximum may arise from a H2O bridge acting as a relay between electrophilic NH and incipient alkoxide ion in the transition state. In the experiment, the researchers used many compounds, for example, 7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6Category: imidazoles-derivatives).

7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Category: imidazoles-derivatives

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Highly Stable Polymeric Ionic Liquid Modified Electrode to Immobilize Ferricyanide for Electroanalysis of Sulfide was written by Chang, Jen-Lin;Wei, Guor-Tzo;Chen, Tsu-Yin;Zen, Jyh-Myng. And the article was included in Electroanalysis in 2013.Product Details of 915358-85-9 This article mentions the following:

We report the preparation and application of a highly stable polymeric ionic liquid-modified electrode to immobilize ferricyanide for sulfide anal. Good long-term stability of the modified electrode verifies its potential in sensor applications. The electrocatalytic sulfide oxidation signal at �.0 V vs. Ag/AgCl in pH 7 PBS at the modified electrode was used for sulfide detection by hydrodynamic chronoamperometry and a detection limit of 12.9nM (S/N =3) was obtained. Practical utility of the system is applied to the determination of sulfides in hot spring water and groundwater. In the experiment, the researchers used many compounds, for example, 1-Butyl-3-vinyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 915358-85-9Product Details of 915358-85-9).

1-Butyl-3-vinyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 915358-85-9) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Product Details of 915358-85-9

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Cu-Catalyzed Regioselective C-H Alkylation of Benzimidazoles with Aromatic Alkenes was written by He, Yu-Ting;Mao, Yang-Jie;Hao, Hong-Yan;Xu, Zhen-Yuan;Lou, Shao-Jie;Xu, Dan-Qian. And the article was included in Organic Letters in 2020.Computed Properties of C8H8N2 This article mentions the following:

Herein we report a novel Cu-catalyzed regioselective C2-H alkylation of benzimidazoles such as N-methylbenzimidazole with aromatic alkenes. The reaction features exclusive regioselectivity and broad substrate scope in the intermol. alkylation of benzimidazoles with terminal and internal aromatic alkenes, constituting a modular access toward benzimidazole-containing 1,1-di(hetero)aryl alkanes such as I. The intramol. C2-H alkylation of benzimidazoles with aromatic alkenes such as N-cinnamylbenzimidazole has been achieved in an endo-selective manner to yield fused benzimidazoles such as cyclopentapyrrolobenzimidazole II. The enantioselective C2 alkylation of benzimidazoles has also been realized with moderate to good stereocontrol; for example, using (S,S)-Ph-BPE, (+)-I and (+)-II were prepared in 85:15 er and 68:32 er, resp. In the experiment, the researchers used many compounds, for example, 1-Methylbenzimidazole (cas: 1632-83-3Computed Properties of C8H8N2).

1-Methylbenzimidazole (cas: 1632-83-3) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Computed Properties of C8H8N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem