Month: February 2023

Bridge-functionalized bisimidazolium bromides as catalysts for the conversion of epoxides to cyclic carbonates with CO₂ was written by Li, Yuanhui;Dominelli, Bruno;Reich, Robert M.;Liu, Boping;Kuhn, Fritz E.. And the article was included in Catalysis Communications in 2019.Recommanded Product: 1-Octyl-1H-imidazole This article mentions the following:

Six novel bridge-functionalized bisimidazolium bromides were synthesized and applied as catalysts for the cycloaddition of carbon dioxide and epoxides to give cyclic carbonates. Addnl., the influence of the hydrogen-bond donors, the N-wing-tip-substituents and the chain length of the connecting carbon bridges on the catalytic activity were studied. Catalyst bis[(trimethylphenyl)imidazoliumyl]methylpropanoic acid dibromide proved to be slightly more active than the reference catalyst bis(octylimidazoliumyl)propanol dibromide for the addition of carbon dioxide to various epoxides and could be analogously recycled from propylene carbonate for at least six times without distinct loss of activity. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Recommanded Product: 1-Octyl-1H-imidazole).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Recommanded Product: 1-Octyl-1H-imidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Mechanism of methylation of 4(or 5)-nitroglyoxaline by methyl sulfate was written by Grimison, A.;Ridd, J. H.. And the article was included in Chemistry & Industry (London, United Kingdom) in 1956.Name: 1-Methyl-4-nitroimidazole This article mentions the following:

A kinetic study was undertaken under homogeneous conditions. The acidity of 4(or 5)-nitroglyoxaline (I) in water was determined from UV spectra, pK 9.22 in aqueous 10% EtOH containing 0.3-0.9N NaOH. The rate was k₂(Me₂SO₄) (G^–), where G^– is the conjugate base of I. The rate of concurrent hydrolysis of Me₂SO₄ (II) was k’₁(Me₂SO₄) + k’₂(Me₂SO₄) (OH^–). At 25掳, k₂ = 1.9 脳 10^-2; k’₂ = 1.6 脳 10^-2; k’₁ = 1.7 脳 10^-1, all in moles 1.^-1 sec.^-1 Kinetic results point to nucleophilic attack by G^– on II, the product being the 1,4-isomer, in contrast to the 1,5-isomer obtained in acidic media, which also causes a different reaction mechanism. In the experiment, the researchers used many compounds, for example, 1-Methyl-4-nitroimidazole (cas: 3034-41-1Name: 1-Methyl-4-nitroimidazole).

1-Methyl-4-nitroimidazole (cas: 3034-41-1) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Name: 1-Methyl-4-nitroimidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Disclosure of mystery of “fairy rings” by chemistry was written by Kawagishi, Hirokazu. And the article was included in Yuki Gosei Kagaku Kyokaishi in 2015.Reference of 26832-08-6 This article mentions the following:

A review on chems. responsible for “fairy rings” of turf grass, their formation through a new purine metabolic pathway, and chem. synthesis of ¹³C,¹⁵N-labeled metabolites. 2-Azahypoxanthine (AHK, I) (rice plant-growth promotor) and imidazole-4-carboxamide (ICA, II) (turf grass growth inhibitor) were isolated from a fairy-ring forming fungus Lepista sordida. AHK was converted into a metabolite, 2-aza-8-oxohypoxanthine (AOH, III) (turf grass growth-promoters), in plants. Afterward, it turned out that these three compounds, fairy chems. (FSc), endogenously exist in plants and are biosynthesized via a new purine metabolic pathway. Furthermore, FCs increased the yields of rice, wheat and other crops in the field experiments In the experiment, the researchers used many compounds, for example, 1H-Imidazole-4-carboxamide (cas: 26832-08-6Reference of 26832-08-6).

1H-Imidazole-4-carboxamide (cas: 26832-08-6) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Reference of 26832-08-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Layered organic-inorganic hybrid materials based on ionic liquid and lead chloride: Insights into the structure and properties was written by Balachandran, Nisha;Suseeladevi, Asha;Periya, Vijayalakshmi Kunduchi;Robert, Temina Mary;Soundiraraju, Bhuvaneswari;Cyriac, Jobin;Mathew, Dona. And the article was included in Journal of Molecular Liquids in 2020.Safety of 1-Methyl-1H-imidazol-3-ium chloride This article mentions the following:

Layered organic-inorganic hybrid materials are an emerging class of materials with excellent stability and outstanding optoelectronic properties. Here, we report the synthesis, characterization and optical properties of hybrid materials formed from lead chloride (PbCl₂)-methylimidazolium chloride (MimCl) and PbCl₂-alkyl methylimidazolium chlorides (AmimCl) of varying alkyl chain lengths viz. Et (C₂mimCl), Bu (C₄mimCl) and hexyl (C₆mimCl). The molar ratio of PbCl₂ to MimCl and AmimCl had a profound influence on the formation and properties of two-dimensional (2D) hybrid materials. The conformations and structural aspects of the synthesized materials with varying substitutions were extensively evaluated and correlated using computational studies. MimCl-PbCl₂, C₂mimCl-PbCl₂ and C₆mimCl-PbCl₂ forms 2D structures while C₄mimCl-PbCl₂ was forming 2D and 1D structures as evident from topog. and morphol. evaluations through at. force microscopy (AFM) and transmission electron microscopy (TEM). The materials synthesized were non-hygroscopic and exhibited excellent thermal stability. The AmimCl-PbCl₂ shows absorption in the UV region with the onset extends to the visible range and exhibits good photoluminescence at 532 nm. These hybrid materials showed a charge carrier lifetimes (10-40 ns) and a photoresponse (photocurrent of the order microamperes) which make them a potential candidate for optoelectronic devices. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Safety of 1-Methyl-1H-imidazol-3-ium chloride).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Safety of 1-Methyl-1H-imidazol-3-ium chloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

A mixed matrix Eu-4,4′-biphenyldicarboxylate coordination polymer film as a fluorescence turn-off sensor to aniline vapor was written by Shen, Mei Lin;Wei, Zhen;Xu, Ling;Liu, Bing;Jiao, Huan. And the article was included in Journal of Solid State Chemistry in 2019.Application In Synthesis of 1-Methyl-3-propylimidazolium Chloride This article mentions the following:

The ionothermal reaction of EuCl₃ with 4,4′-biphenyldicarboxylic acid (H₂BPDC) produced a 3-dimensional fluorescence coordination polymer (CP), [PMI]₂[Eu₂(BPDC)₃Cl₂] (1). 1 Was dispersed onto the bandage, and further infiltrated by polyvinylidene fluoride (PVDF) to give a mixed matrix 1@PVDF/bandage composite film (1-film). The fluorescence and the morphol. indicate 1-film can emit red fluorescence and the CP particles are on the surfaces of bandage fabrics with the adhesion of PVDF. The fluorescence of 1-film can be quenched by different amines in the order of aliphatic amine > aromatic amine > alc. amine > amide, which concerns with the amine sizes. 1-film shows a fast response and selective sensing to aniline vapor, suggesting it may be a fluorescence turn-off sensor to aniline vapor. In the experiment, the researchers used many compounds, for example, 1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8Application In Synthesis of 1-Methyl-3-propylimidazolium Chloride).

1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Application In Synthesis of 1-Methyl-3-propylimidazolium Chloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Solvent Water Content as a Factor in the Design of Metal Ion Extraction Systems Employing Ionic Liquids was written by Hawkins, Cory A.;Rigney, Madison L.;Rud, Anna;Dietz, Mark L.. And the article was included in Solvent Extraction and Ion Exchange in 2018.SDS of cas: 21252-69-7 This article mentions the following:

In the extraction of strontium nitrate from aqueous nitric acid solutions into a series of hydrophobic N-(1-hydroxyalkyl)-N’-alkylimidazolium bis[(trifluoromethyl)sulfonyl]imides by dicyclohexano-18-crown-6, a correlation has been demonstrated between the conditional extraction constant of strontium (K’_ex,Sr) and the concentration of water in the equilibrated ionic liquid (IL) phase. Despite the absence of a hydroxyl group on the IL cation, essentially the same relationship is observed for the analogous N,N’-dialkylimidazolium ILs. In both instances, the correlation is attributed to the coextn. of the hydrated nitrate ion and its solvation by the hydrated diluent. Transitions of water in the attenuated total reflectance-IR spectra of the ILs are consistent with the existence of multiple states of water. The extraction efficiency for a given water content is greater for the ILs examined than for conventional solvents (i.e., n-alcs.). When coupled with existing knowledge of the factors influencing cation partitioning into ILs, these results provide insight into the IL structural characteristics required to effect efficient metal ion extraction from acidic media. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7SDS of cas: 21252-69-7).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.SDS of cas: 21252-69-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Optimized one-step synthesis and characterization of 1-methyl-4,5-dinitro-1H-imidazole was written by Luo, Jin;Liu, Yu-Cun;Liu, Yan;Chai, Tao. And the article was included in Chemistry of Heterocyclic Compounds (New York, NY, United States) in 2017.Recommanded Product: 1-Methyl-4-nitroimidazole This article mentions the following:

Highly pure 1-methyl-4,5-dinitro-1H-imidazole was obtained from N-methylimidazole in 79% yield. The process was optimized with regard to nitrating mixture composition and the ratio of N-methylimidazole and nitrating mixture The effects of reaction temperature, time, and the rate of nitrating mixture addition were analyzed. The endothermic peak due to melting was obvious on the DSC curve at 75掳, decomposition started at about 250掳, and the main exothermic decomposition peak was at 278.5掳, which indicated that this compound has good thermal stability. In the experiment, the researchers used many compounds, for example, 1-Methyl-4-nitroimidazole (cas: 3034-41-1Recommanded Product: 1-Methyl-4-nitroimidazole).

1-Methyl-4-nitroimidazole (cas: 3034-41-1) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Recommanded Product: 1-Methyl-4-nitroimidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Spontaneous emulsification in ionic liquid/water systems and its use for templating of solids was written by Kowacz, Magdalena;Esperanca, Jose M. S. S.;Rebelo, Luis Paulo N.. And the article was included in Soft Matter in 2014.Recommanded Product: 404001-48-5 This article mentions the following:

Reported is the spontaneous formation of nano-sized ionic liquid/water (IL/W) emulsions in a simple system solely composed of an IL and aqueous solution of an inorganic salt. The IL ions play a dual role, that of both a surfactant and the dispersed phase. No extra surfactant is needed to promote emulsification. Droplets generation at the IL/W interface is captured by nanoparticulate and porous films that imprint the morphol. of this unstable interface. The emulsion droplets are employed to create core-shell microcrystals with potential functionality. In the experiment, the researchers used many compounds, for example, 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5Recommanded Product: 404001-48-5).

3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Recommanded Product: 404001-48-5

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Study of plant growth regulators detection technology based on terahertz spectroscopy was written by Chen, Xi-ai;Wu, Xue;Zhang, Song;Wang, Ling. And the article was included in Guangpuxue Yu Guangpu Fenxi in 2018.Category: imidazoles-derivatives This article mentions the following:

The terahertz spectra of gibberellin, forchlorfenuron and thidiazuron in the range of 0.2 to 2.0 THz were obtained by THz time-domain spectroscopy, based on which their absorption and refraction spectra were calculated The results showed that all of them had obvious characteristic absorption peaks in the terahertz band. The terahertz absorption spectra of nineteen different substances were classified and tested by least squares support vector machine. Particle swarm optimization and genetic algorithm were applied for the parameter optimization of the least squares support vector machine, and the stability of the model was tested with noise addition This study demonstrates the feasibility of terahertz spectroscopy for identification of plant growth regulators and will provide a new approach for the detection of plant growth regulators. In the experiment, the researchers used many compounds, for example, 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate (cas: 145040-37-5Category: imidazoles-derivatives).

1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate (cas: 145040-37-5) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Category: imidazoles-derivatives

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Prop-2-en-1-yl 4-(4,5-diphenyl-1H-imidazol-2-yl)benzoate was written by Mohamed, Shaaban K.;Akkurt, Mehmet;Marzouk, Adel A.;Abdelhamid, Antar A.;Santoyo-Gonzalez, Francisco. And the article was included in Acta Crystallographica, Section E: Structure Reports Online in 2013.Category: imidazoles-derivatives This article mentions the following:

Prop-2-en-1-yl 4-(4,5-diphenyl-1H-imidazol-2-yl)benzoate, C₂₅H₂₀N₂O₂, crystallized with 2 mols. in the asym. unit, in 1 of which the atoms of the terminal propenyl group are disordered over 2 sets of sites, with a refined occupancy ratio of 0.870(4):0.130(4). The central imidazole ring makes dihedral angles of 25.51(11), 40.73(11) and 27.36(11)掳 with the 3 pendant rings in 1 mol. and 22.56(10), 60.72(10) and 5.85(10)掳 in the other. In the crystal, mols. are linked by N-H路路路N and C-H路路路O H bonds, forming a 3-dimensional network. The crystal structure also features C-H路路路蟺 interactions and 蟺-蟺 stacking [centroid-centroid distances = 3.8834(18) and 3.9621(17) 脜] interactions. Crystallog. data are given. In the experiment, the researchers used many compounds, for example, 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoic acid (cas: 5496-35-5Category: imidazoles-derivatives).

4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoic acid (cas: 5496-35-5) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Category: imidazoles-derivatives

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem