Ding, Wei et al. published their research in Yingyong Huaxue in 2013 | CAS: 21252-69-7

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. HPLC of Formula: 21252-69-7

Synthesis of novel cationic copolymer acrylamide/acrylic acid ester by single electron transfer living radical polymerization in aqueous solution was written by Ding, Wei;Liu, Kang;Luan, Huoxin;Yu, Tao;Qu, Guangmiao. And the article was included in Yingyong Huaxue in 2013.HPLC of Formula: 21252-69-7 This article mentions the following:

The imidazole, acrylonitrile, bromooctane were used to synthesize a new cationic polymerizable ionic liquid surfactant named chlorinated-1-octyl-3-(4-butylacrylate-based) imidazole (PMOIH8). Using 2-chloropropylamide (MPC) as the initiator, Cu0 powder and tris-(2-dimethylamino ethyl) amine (Me6-TREN) as the catalyst, a new kind of copolymer acrylamide/acrylic ester was synthesized via single electron transfer living radical polymerization (SET-LRP) of acrylamide with PMOIH8. The resulting polymers were analyzed by FT-IR, MS and 1H NMR, and the results showed that the polymers were target products. The relative mol. mass and the distribution of the resulting polymer were determined by GPC. The relative mol. mass of polymers is within the range of 2 脳 103鈭?4 脳 103, and the relative mol. mass distribution is within the range of 1.21鈭?.75. Various factors which might affect the SET-LRP such as catalyst and initiator were discussed. The results showed that as the amount of catalyst reduced, the polymerization rate decreased and the polymerization rate constant (kpapp) reduced from 0.0168 min-1 to 0.0065 min-1, while the relative mol. mass distribution Mw/Mn increased from 1.25鈭?.71 to 1.32鈭?.75, and the initiator efficiency decreased, Ieff = 90.24%. As the amount of initiator increased, the relative mol. mass distribution of the resulting polymer was narrower with Mw/Mn reduced from 1.25鈭?.71 to 1.21鈭?.68, while the polymerization rate constant(kpapp) increased from 0.0168 min-1 to 0.0201 min-1, and the initiator efficiency increased, Ieff = 93.17%. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7HPLC of Formula: 21252-69-7).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. HPLC of Formula: 21252-69-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Gheitasi Zarooni, Mahtab et al. published their research in Journal of Inorganic and Organometallic Polymers and Materials in 2020 | CAS: 35487-17-3

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Quality Control of 1-Methyl-1H-imidazol-3-ium chloride

Pd/[C2NH2mim][Br] Thin Film Versus Pd/[C8mim][Cl] or Pd/[C8mim][BF4]: Catalytic Applications in Electrooxidation of Methanol, p-Nitrophenol Reduction and C-C Coupling Reaction was written by Gheitasi Zarooni, Mahtab;Hoseini, S. Jafar;Bahrami, Mehrangiz;Roushani, Mahmoud;Nabavizadeh, S. Masoud. And the article was included in Journal of Inorganic and Organometallic Polymers and Materials in 2020.Quality Control of 1-Methyl-1H-imidazol-3-ium chloride This article mentions the following:

In this study, different ionic liquids including 1-aminoethyl-3-methyl-imidazolium bromide [C2NH2mim][Br] (1), 1-methyl-3-octylimidazolium chloride [C8mim][Cl] (2) and 1-methyl-3-octylimidazolium tetrafluoroborate [C8mim][BF4] (3) were applied to stabilize Pd nanoparticles (NPs) at toluene/water interface as thin films. Field emission-SEM (FE-SEM) images showed puckered chains of ionic liquid (1) around the Pd NPs as flower nanostructures. Transmission electron microscopy (TEM) image of Pd/1 showed clearly core-shell nanostructures. Furthermore, applications of Pd/1, Pd/2 and Pd/3 were investigated in the Suzuki-Miyaura C-C coupling reaction in the presence and absence of ultrasonic waves, hydrogenation catalysis of p-nitrophenol reduction and methanol oxidation reaction. Interestingly, Jf (forwarding c.d. due to methanol oxidation) was observed only for Pd/1. We believe that interactions of -NH2 and imidazolium groups of ionic liquid 1 with Pd particles are very important in producing of puckered shells around the Pd NPs. Injection of electron d. from -NH2 group and Br of ionic liquid 1 to Pd content tends to Pd be softer than other ionic liquids (2 or 3). This effect weakens the strength of Pd-O and facilitates the intermol. reductive elimination between Pd-O and Pd-C鈮僌 in rate-determining step of methanol oxidation to produce CO2 product. However, electron releasing group accelerates the increasement in neg. charge d. of metal accelerates intramol. or intermol. reduction elimination. Graphic Abstract: Stabilization of Pd nanoparticles from organometallic precursor in the presence of various ionic liquids is investigated. The obtained Pd/ionic liquid thin films were applied in catalytic reactions such as Suzuki-Miyaura C-C coupling reaction, p-nitrophenol reduction and methanol oxidation process for fuel cells. In spite of Pd nanoparticle thin films used for methanol oxidation reaction that exhibit no considerable methanol oxidation, these catalysts exhibit good electrocatalytic activity. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Quality Control of 1-Methyl-1H-imidazol-3-ium chloride).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Quality Control of 1-Methyl-1H-imidazol-3-ium chloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Dong, Shi-Jia et al. published their research in International Journal of Polymer Science in 2015 | CAS: 35487-17-3

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Safety of 1-Methyl-1H-imidazol-3-ium chloride

An efficient process for pretreatment of lignocelluloses in functional ionic liquids was written by Dong, Shi-Jia;Zhang, Bi-Xian;Gao, Yun-Fei;Hu, Xiao-Mei. And the article was included in International Journal of Polymer Science in 2015.Safety of 1-Methyl-1H-imidazol-3-ium chloride This article mentions the following:

The complex structure of the lignocelluloses is the main obstacle in the conversion of lignocellulosic biomass into valuable products. Ionic liquids provide the opportunities for their efficient pretreatment for biomass. Therefore, in this work, pretreatment of corn stalk was carried out in ultrasonic-assisted ionic liquid including 1-butyl-3-methylimidazolium chloride [BMIM]Cl, 1-H-3-methylimidazolium chloride [HMIM]Cl, and 1-(1-propylsulfonic)-3-imidazolium chloride [HSO3-pMIM]Cl at 70掳C for 2 h.We compared the pretreatments by ionic liquid with and without the addition of deionized water. Fourier transform IR spectroscopy (FTIR) and SEM were employed to analyze the chem. characteristics of regenerated cellulose-rich materials. [HMIM]Cl and [HSO3-pMIM]Cl were effective in lignin extraction to obtain cellulose-rich materials. FTIR anal. and SEM anal. indicated the effective lignin removal and the reduced crystallinity of cellulose-rich materials. Enzymic hydrolysis of cellulose-rich materials was performed efficiently. High yields of reducing sugar and glucose were obtained when the corn stalk was pretreated by [HMIM]Cl and [HSO3-pMIM]Cl. Ionic liquids provided the ideal environment for lignin extraction and enzymic hydrolysis of corn stalk and [HMIM]Cl and [HSO3-pMIM]Cl proved the most efficient ionic liquids This simple and environmentally acceptable method has a great potential for the preparation of bioethanol for industrial production In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Safety of 1-Methyl-1H-imidazol-3-ium chloride).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Safety of 1-Methyl-1H-imidazol-3-ium chloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Shi, Yueting et al. published their research in Journal of Molecular Liquids in 2021 | CAS: 21252-69-7

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Recommanded Product: 21252-69-7

Strengthened adsorption and corrosion inhibition of new single imidazole-type ionic liquid molecules to copper surface in sulfuric acid solution by molecular aggregation was written by Shi, Yueting;Fu, Yan;Xu, Shenying;Huang, Haijun;Zhang, Shengtao;Wang, Zhenqiang;Li, Wenpo;Li, Hongru;Gao, Fang. And the article was included in Journal of Molecular Liquids in 2021.Recommanded Product: 21252-69-7 This article mentions the following:

This study proposes to use mol. aggregation method of organic ionic liquid mols. (OILMs) to intensify adsorption and corrosion inhibition to copper surface in sulfuric acid solution Three new single imidazole-type OILMs including long carbon chain were synthesized, which were characterized by different methods such as NMR (NMR) and elemental anal. The results suggest that the OILMs could process regular mol. assembly in sulfuric acid solution The formed OILMs aggregates have been shown dependence on the OILMs concentrations and aggregation time. The chem. adsorption of the OILMs aggregates on copper surface was demonstrated by various means including attenuated total reflection IR spectroscopy (ATR-IR), XPS, X-ray diffraction (XRD), and spectroscopic ellipsometry and contacting angles, and at. force microscopy (AFM) as well as SEM (SEM) imaging. Thus, the hydrophobic adsorption layers of the OILMs aggregates were yielded on copper surface. The electrochem. survey suggests that the OILMs aggregates present nice corrosion resistance effect to copper in sulfuric acid solution (the maximal corrosion inhibition efficiency, >93%). The results were further understood by the theor. simulation computation. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Recommanded Product: 21252-69-7).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Recommanded Product: 21252-69-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Zhang, Mengchu et al. published their research in Advanced Synthesis & Catalysis in 2020 | CAS: 85692-37-1

1-(1-Methyl-1H-imidazol-2-yl)ethanone (cas: 85692-37-1) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3鈥揅6) is higher than in water and generally decreases with a Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Safety of 1-(1-Methyl-1H-imidazol-2-yl)ethanone

Diastereoselective Trapping of Transient Carboxylic Oxonium Ylides with 伪,尾-Unsaturated 2-Acyl Imidazoles was written by Zhang, Mengchu;Zhang, Tianyuan;Zhang, Dan;Hu, Wenhao. And the article was included in Advanced Synthesis & Catalysis in 2020.Safety of 1-(1-Methyl-1H-imidazol-2-yl)ethanone This article mentions the following:

A diastereoselective reaction of cyclopropene carboxylic acids with 伪,尾-unsaturated 2-acyl imidazoles was developed to report a Michael-type trapping of transient carboxylic oxonium ylides. This transformation provided a direct approach for the construction of valuable 纬-butenolide derivatives I [R1 = Ph, 4-FC6H4, 3,4,5-trimethoxyphenyl, etc.; R2 = Ph, 2-furyl, 4-NCC6H4, etc.] in good yields (60-99%) with high diastereoselectivities (up to >95:5 dr) under mild reaction conditions. In the experiment, the researchers used many compounds, for example, 1-(1-Methyl-1H-imidazol-2-yl)ethanone (cas: 85692-37-1Safety of 1-(1-Methyl-1H-imidazol-2-yl)ethanone).

1-(1-Methyl-1H-imidazol-2-yl)ethanone (cas: 85692-37-1) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3鈥揅6) is higher than in water and generally decreases with a Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Safety of 1-(1-Methyl-1H-imidazol-2-yl)ethanone

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Wang, Yan et al. published their research in ACS Pharmacology & Translational Science in 2020 | CAS: 145040-37-5

1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate (cas: 145040-37-5) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Name: 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate

Serelaxin and the AT2 Receptor Agonist CGP42112 Evoked a Similar, Nonadditive, Cardiac Antifibrotic Effect in High Salt-Fed Mice That Were Refractory to Candesartan Cilexetil was written by Wang, Yan;Han, Lei;Shen, Matthew;Jones, Emma S.;Spizzo, Iresha;Walton, Sarah L.;Denton, Kate M.;Gaspari, Tracey A.;Samuel, Chrishan S.;Widdop, Robert E.. And the article was included in ACS Pharmacology & Translational Science in 2020.Name: 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate This article mentions the following:

Fibrosis is involved in the majority of cardiovascular diseases and is a key contributor to end-organ dysfunction. In the current study, the antifibrotic effects of recombinant human relaxin-2 (serelaxin; RLX) and/or the AT2R agonist CGP42112 (CGP) were compared with those of the established AT1R antagonist, candesartan cilexetil (CAND), in a high salt-induced cardiac fibrosis model. High salt (HS; 5%) for 8 wk did not increase systolic blood pressure in male FVB/N mice, but CAND treatment alone significantly reduced systolic blood pressure from HS-induced levels. HS significantly increased cardiac interstitial fibrosis, which was reduced by either RLX and/or CGP, which were not additive under the current exptl. conditions, while CAND failed to reduce HS-induced cardiac fibrosis. The antifibrotic effects induced by RLX and/or CGP were associated with reduced myofibroblast differentiation. Addnl., all treatments inhibited the HS-induced elevation in tissue inhibitor of matrix metalloproteinases-1, together with trends for increased MMP-13 expression, that collectively would favor collagen degradation Furthermore, these antifibrotic effects were associated with reduced cardiac inflammation. Collectively, these results highlight that either RXFP1 or AT2R stimulation represents novel therapeutic strategies to target fibrotic conditions, particularly in HS states that may be refractory to AT1R blockade. In the experiment, the researchers used many compounds, for example, 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate (cas: 145040-37-5Name: 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate).

1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate (cas: 145040-37-5) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Name: 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Zhang, Jingjing et al. published their research in Journal of Inclusion Phenomena and Macrocyclic Chemistry in 2014 | CAS: 404001-48-5

3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Application of 404001-48-5

Further understanding of the multiple equilibria interaction pattern between ionic liquid and 尾-cyclodextrin was written by Zhang, Jingjing;Shi, Jianfeng;Shen, Xinghai. And the article was included in Journal of Inclusion Phenomena and Macrocyclic Chemistry in 2014.Application of 404001-48-5 This article mentions the following:

The interactions of the ionic liquids 1-alkyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide (CnmimTf2N, n = 2, 4, 6, 8, 10, 12) with 尾-cyclodextrin (尾-CD) in aqueous solutions are investigated in this work. The stoichiometry and apparent association constants are obtained by competitive fluorescence method and isothermal titration calorimetry (ITC). The results show that C2mimTf2N, C4mimTf2N, and C6mimTf2N mainly form 1:1 (guest:host) inclusion complexes with 尾-CD, whereas C8mimTf2N, C10mimTf2N, and C12mimTf2N form both 1:1 and 1:2 inclusion complexes, the latter of which are mainly attributed to the formation of the Cnmim+-2尾-CD complexes. Besides, Tf2N only forms the 1:1 complex with 尾-CD owing to a charge resonance structure that breaks the symmetry of the structure of Tf2N, which is proved by Fourier transform IR spectra. The thermodn. parameters obtained by ITC reveal that the formation of the inclusion complexes are enthalpy-controlled for C2mimTf2N, C4mimTf2N, and C6mimTf2N, while for the C8mimTf2N/尾-CD system, the process becomes entropy and enthalpy driven. Based on high-resolution mass spectrometry used with electrospray ionization results, the interaction between CnmimTf2N and 尾-CD is found to follow the multiple equilibrium interaction pattern which was suggested in our previous work. In the experiment, the researchers used many compounds, for example, 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5Application of 404001-48-5).

3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Application of 404001-48-5

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Zhang, Jing et al. published their research in Macromolecular Rapid Communications in 2016 | CAS: 915358-85-9

1-Butyl-3-vinyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 915358-85-9) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Reference of 915358-85-9

CO2 Responsive Imidazolium-Type Poly(Ionic Liquid) Gels was written by Zhang, Jing;Xu, Dan;Guo, Jiangna;Sun, Zhe;Qian, Wenjing;Zhang, Ye;Yan, Feng. And the article was included in Macromolecular Rapid Communications in 2016.Reference of 915358-85-9 This article mentions the following:

Poly(ionic liquid) (PIL) gels with CO2 stimulus responsiveness were synthesized through the copolymerization of an imidazolium-type ionic liquid monomer with 2-(di-Me amino) Et methacrylate. Upon bubbling with CO2 gas, the prepared PIL solution is converted to a transparent and stable gel, which can be turned back to the initial solution state after N2 bubbling. The reversible sol-gel phase transition behavior is proved by the reversible values of viscosity and ionic conductivity The possible mechanism for such a reversible sol-gel phase transition is demonstrated by NMR, conductivity, and rheol. measurements. In the experiment, the researchers used many compounds, for example, 1-Butyl-3-vinyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 915358-85-9Reference of 915358-85-9).

1-Butyl-3-vinyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 915358-85-9) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Reference of 915358-85-9

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Backler, Frederick et al. published their research in Australian Journal of Chemistry in 2021 | CAS: 3034-41-1

1-Methyl-4-nitroimidazole (cas: 3034-41-1) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Safety of 1-Methyl-4-nitroimidazole

NMR Chemical Shift and Methylation of 4-Nitroimidazole: Experiment and Theory* was written by Backler, Frederick;Sani, Marc Antoine;Separovic, Frances;Vasilyev, Vladislav;Wang, Feng. And the article was included in Australian Journal of Chemistry in 2021.Safety of 1-Methyl-4-nitroimidazole This article mentions the following:

Nitroimidazoles and derivatives are a class of active pharmaceutical ingredients (APIs) first introduced sixty years ago. As anti-infection agents, the structure-activity relationships of nitroimidazole compounds have been particularly difficult to study due to their low reduction potentials and unique electronic structures. In this study, we combine dynamic nuclear polarization (DNP)-enhanced solid-state (100K), solid-state (298K), and 1H-13C heteronuclear single quantum coherence (HSQC) solution-state NMR techniques (303K) with d. functional theory (DFT) to study the 1H, 13C, and 15N chem. shifts of 4-nitroimidazole (4-NI) and 1-methyl-4-nitroimidazole (CH3-4NI). The 4-NI chem. shifts were observed at 119.4, 136.4, and 144.7ppm for 13C, and at 181.5, 237.4, and 363.0ppm for 15N. The measurements revealed that methylation (deprotonation) of the amino nitrogen N(1) of 4-NI had less effect (螖未=-4.8ppm) on the N(1) chem. shift but was compensated by shielding of the N(3) (螖未=11.6ppm) in CH3-4NI. The calculated chem. shifts using DFT for 4-NI and CH3-4NI agreed well with the exptl. values (within 2%) for the imidazole carbons. However, larger discrepancies (up to 13%) were observed between the calculated and measured 15N NMR chem. shifts for the imidazole nitrogen atoms of both mols., which indicate that effects such as imidazole ring resonant structures and mol. dynamics may also contribute to the nitrogen chem. environment. In the experiment, the researchers used many compounds, for example, 1-Methyl-4-nitroimidazole (cas: 3034-41-1Safety of 1-Methyl-4-nitroimidazole).

1-Methyl-4-nitroimidazole (cas: 3034-41-1) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Safety of 1-Methyl-4-nitroimidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Thota, Ganesh Kumar et al. published their research in Advanced Synthesis & Catalysis in 2018 | CAS: 85692-37-1

1-(1-Methyl-1H-imidazol-2-yl)ethanone (cas: 85692-37-1) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3鈥揅6) is higher than in water and generally decreases with a Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Recommanded Product: 85692-37-1

Enantioselective Conjugate Addition of 2-Acylimidazoles with Nitroalkenes Promoted by Chiral-at-Metal Rhodium(III) Complexes was written by Thota, Ganesh Kumar;Sun, Gui-Jun;Deng, Tao;Li, Yi;Kang, Qiang. And the article was included in Advanced Synthesis & Catalysis in 2018.Recommanded Product: 85692-37-1 This article mentions the following:

An enantioselective conjugate addition of 2-acylimidazoles with nitroalkenes catalyzed by chiral-at-metal rhodium(III) complex under mild reaction conditions was developed, affording versatile 纬-nitro ketone skeletons in good yields with excellent enantioselectivities (up to >99% ee). In the experiment, the researchers used many compounds, for example, 1-(1-Methyl-1H-imidazol-2-yl)ethanone (cas: 85692-37-1Recommanded Product: 85692-37-1).

1-(1-Methyl-1H-imidazol-2-yl)ethanone (cas: 85692-37-1) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3鈥揅6) is higher than in water and generally decreases with a Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Recommanded Product: 85692-37-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem