Month: February 2023

Alkyl substituent effect on density, viscosity and chemical behavior of 1-alkyl-3-methylimidazolium chloride was written by Olmo, Lourdes del;Lage-Estebanez, Isabel;Lopez, Rafael;Garcia de la Vega, Jose M.. And the article was included in Journal of Molecular Modeling in 2014.Reference of 79917-89-8 This article mentions the following:

Mol. structure of the conformers of 1-C_n-3-methylimidazolium chloride (n = 1 to 4) ionic liquids has been explored and the relationships with d. and viscosity have been studied using COSMO related methodologies. Effects of the number of conformers, ionic character, anion-cation relative positions and the alkyl chain length of the cation on predictions of properties have been analyzed. The quality of the predictions has been tested by comparing with exptl. results. Moreover, COSMO polarization charge densities, σ-profiles and σ-potentials of the conformers have been analyzed. Predictions on the chem. behavior based on the values of these properties in the conformers have been used to elucidate the affinity for electrophilic and nucleophilic reagents of ionic liquids In the experiment, the researchers used many compounds, for example, 1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8Reference of 79917-89-8).

1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Reference of 79917-89-8

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Structural, spectroscopic, and electrochemical properties of tri- and tetradentate N₃ and N₃S copper complexes with mixed benzimidazole/thioether donors was written by Castillo, Ivan;Ugalde-Saldivar, Victor M.;Rodriguez Solano, Laura A.;Sanchez Eguia, Brenda N.;Zeglio, Erica;Nordlander, Ebbe. And the article was included in Dalton Transactions in 2012.Recommanded Product: 1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde This article mentions the following:

Cupric and cuprous complexes of bis(2-methylbenzimidazolyl)(2-methylthiophene)amine (L¹), bis(2-methylbenzimidazolyl)benzylamine (L²), bis(2-methylbenzimidazolyl)(2,4-dimethylphenylthioethyl)amine (L³), bis(1-methyl-2-methylbenzimidazolyl)benzylamine (Me₂L²), and bis(1-methyl-2-methylbenzimidazolyl)(2,4-dimethylphenylthioethyl)amine (Me₂L³) were spectroscopically, structurally, and electrochem. characterized. The thioether-containing ligands L³ and Me₂L³ give rise to complexes with Cu-S bonds in solution and in the solid state, as evidenced by UV-visible spectroscopy and x-ray crystallog. The Cu²⁺ complexes [L¹CuCl₂] (1), [L²CuCl₂] (2) and [Me₂L³CuCl]ClO₄ (3^Me,ClO4) are monomeric in solution according to ESI mass spectrometry data, as well as in the solid state. Their Cu⁺ analogs [L¹Cu]ClO₄, [L²Cu]ClO₄, [L³Cu]ClO₄ (4–6), [BOC₂L¹Cu(NCCH₃)]ClO₄ (4^BOC), [Me₂L²Cu(NCCH₃)₂]PF₆ (5^Me) and [Me₂L³Cu]₂(ClO₄)₂ (6^Me) are also monomeric in MeCN solution, as confirmed crystallog. for 4^BOC and 5^Me. In contrast, 6^Me is dimeric in the solid state, with the thioether group of one of the ligands bound to a symmetry-related Cu⁺ ion. Cyclic voltammetry studies revealed that the bis(2-methylbenzimidazolyl)amine-Cu²⁺/Cu⁺ systems possess half-wave potentials in the range -0.16 to -0.08 V (referenced to the ferrocenium-ferrocene couple); these values are nearly 0.23 V less neg. than those reported for related bis(picolyl)amine-derived ligands. Based on these observations, the N₃ or N₃S donor set of the benzimidazole-derived ligands is analogous to previously reported chelating systems, but the electronic environment they provide is unique, and may have relevance to histidine and methionine-containing metalloenzymes. This is also reflected in the reactivity of [Me₂L²Cu(NCCH₃)₂]⁺ (5^Me) and [Me₂L³Cu]⁺ (6^Me) towards dioxygen, which gave the superoxide anion in both cases. The thioether-bound Cu⁺ center in 6^Me appears to be more selective in the generation of O₂âˆ?sup>- than 5^Me, lending evidence to the hypothesis of the modulating properties of thioether ligands in Cu-O₂ reactions. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde (cas: 3012-80-4Recommanded Product: 1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde).

1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde (cas: 3012-80-4) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Recommanded Product: 1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Extraction desulfurization of alkylimidazolium chlorate ionic liquid was written by Yan, Wen-chao;Wang, Qiang;Zhou, Ming-dong;Xiao, Jing;Zang, Shu-liang. And the article was included in Shiyou Huagong Gaodeng Xuexiao Xuebao in 2012.Application In Synthesis of 1-Methyl-3-propylimidazolium Chloride This article mentions the following:

A series of alkylimidazolium chlorate type of ionic liquids (ILs) bearing different length of alkyl chains were synthesized. The desulfurization for the model or true oil using ILS as extracting agent were investigated under different conditions. The results show that the best desulfurization rate was obtained after 90 min under the condition of V_[C7min]ClO3/V_Oil = 5 : 1 at 60°C using [C₇min]ClO₃ as extracting reagent. The sulfur removal reached 82.15% for the model oil ([S]₀ = 1160 μg/g) 56.09% for the FCC gasoline ([S]₀ = 117 μg/g) and 53.01% for the FCC diesel ([S]₀ = 1974 μg/g). After the reaction, the fuel oil and ionic liquid can be separated simply by decantation. The ILs were then purified by fractional distillation The ILs can be recycled at least for 5 times without significant loss of activity. In the experiment, the researchers used many compounds, for example, 1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8Application In Synthesis of 1-Methyl-3-propylimidazolium Chloride).

1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Application In Synthesis of 1-Methyl-3-propylimidazolium Chloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Molecular Parameters and Transmembrane Transport Mechanism of Imidazolium-Functionalized Binols was written by Vidal, Marc;Schmitzer, Andreea. And the article was included in Chemistry – A European Journal in 2014.HPLC of Formula: 21252-69-7 This article mentions the following:

We describe the mol. parameters governing the transmembrane activity of imidazolium-functionalized anion transporters and present a detailed mechanistic study. These ionophores adopt a mobile-carrier mechanism for short Me and Bu chains, a combined mobile-carrier/transmembrane-pore mechanism for octyl and dodecyl chains, and form transmembrane aggregates for hexadecyl chains. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7HPLC of Formula: 21252-69-7).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.HPLC of Formula: 21252-69-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Carbohydrates-tailored phase tunable systems composed of ionic liquids and water was written by Chen, Yuhaun;Wang, Yige;Cheng, Qingyan;Liu, Xiaoli;Zhang, Suojiang. And the article was included in Journal of Chemical Thermodynamics in 2009.SDS of cas: 79917-89-8 This article mentions the following:

Phase behaviors of 1-alkyl-3-methylimidazolium derivatives [C_nmim]X (n = 2 to 10, X = Cl^–, Br^–, BF₄^–)-carbohydrate-H₂O were systemically investigated. For hydrophilic ILs, 1-alkyl-3-methylimidazolium tetrafluoroborate [C_nmim]BF₄ (n = 3, 4), the homogeneous aqueous solution can be induced to form two aqueous phases by addition of carbohydrate. For hydrophobic ILs, [C_nmim]BF₄ (n = 5 to 10), the mutual solubility with water can be lowered by addition of carbohydrate. Aqueous solutions of 1-alkyl-3-Me imidazolium chlorides ([C_nmim]Cl, n = 2 to 10) and 1-alkyl-3-Me imidazolium bromides ([C_nmim]Br, n = 2 to 10) do not form aqueous two-phase systems (ATPSs) with carbohydrate at 242.15-373.15 K. The high partitioning behavior of phenol in the system [C_nmim]BF₄ (n = 3 to 10) (1) + carbohydrate (2) + H₂O (3) shows that carbohydrate-tailored {IL + H₂O} systems are feasible to be used as extraction systems, especially in biol. and environmental engineering. In the experiment, the researchers used many compounds, for example, 1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8SDS of cas: 79917-89-8).

1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.SDS of cas: 79917-89-8

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Odd-even effect on the formation of aqueous biphasic systems formed by 1-alkyl-3-methylimidazolium chloride ionic liquids and salts was written by Belchior, Diana C. V.;Sintra, Tania E.;Carvalho, Pedro J.;Soromenho, Mario R. C.;Esperanca, Jose M. S. S.;Ventura, Sonia P. M.;Rogers, Robin D.;Coutinho, Joao A. P.;Freire, Mara G.. And the article was included in Journal of Chemical Physics in 2018.Product Details of 79917-89-8 This article mentions the following:

This work provides a comprehensive evaluation of the effect of the cation alkyl side chain length of the 1-alkyl-3-methylimidazolium chloride series ([C_nC₁i.m.]Cl, n = 2-14) of ionic liquids (ILs) on their capability to form aqueous biphasic systems (ABSs) with salts and self-aggregation derived properties. The liquid-liquid phase behavior of ternary systems composed of [C_nC₁i.m.]Cl, water, and K₃PO₄ or K₂CO₃ and the resp. Setschenow salting-out coefficients (k_s), a quant. measure of the two-phase formation ability, were determined An odd-even effect in the k_s values along the number of methylene groups of the longest IL cation alkyl side chain was identified for the ABS formed by K₂CO₃, a weaker salting-out agent where the phenomenon is clearly identified. In general, cations with even alkyl side chains, being likely to display higher molar volumes, are more easily salted-out and thus more prone to undergo phase separation The odd-even effect in the k_s values is, however, more significant in ILs up to n = 6, where the nanostructuration/nanosegregation of ILs plays a less relevant role. Still, with the [C_nC₁i.m.]Cl (n = 7-14) series of ILs, an odd-even effect was also identified in the ILs’ ionization degree, molar conductivity, and conductivity at infinite dilution In summary, it is shown here that the ILs’ odd-even effect occurs in IL aqueous solutions and not just in neat ILs, an already well-established phenomenon occurring in a series of ILs’ properties described as a result of the orientation of the terminal Me groups to the imidazolium ring cation and consequent effect in the ILs’ cohesive energy. (c) 2018 American Institute of Physics. In the experiment, the researchers used many compounds, for example, 1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8Product Details of 79917-89-8).

1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Product Details of 79917-89-8

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis of O,C-dilithium derivatives of 2-(α-hydroxyalkyl)-1-methylbenzimidazoles was written by Morkovnik, A. S.;Tertov, B. A.. And the article was included in Chemistry of Heterocyclic Compounds (New York, NY, United States)(Translation of Khimiya Geterotsiklicheskikh Soedinenii) in 2001.Related Products of 3012-80-4 This article mentions the following:

Methylbenzimidazoles reacted with lithionaphthalene and lithium in THF forming dilithiated methylbenzimidazole derivatives which reacted with benzaldehyde yielding (methylbenzimidazolyl)phenylalkyldiols. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde (cas: 3012-80-4Related Products of 3012-80-4).

1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde (cas: 3012-80-4) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Related Products of 3012-80-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

In Situ Formation of Frustrated Lewis Pairs in a Water-Tolerant Metal-Organic Framework for the Transformation of CO₂ was written by Shyshkanov, Serhii;Nguyen, Tu N.;Ebrahim, Fatmah Mish;Stylianou, Kyriakos C.;Dyson, Paul J.. And the article was included in Angewandte Chemie, International Edition in 2019.Category: imidazoles-derivatives This article mentions the following:

Herein, a bulky Lewis acid-functionalized ligand incorporated into a water-tolerant metal-organic framework (MOF), named SION-105 and employing Lewis basic diamine substrates for the in situ formation of FLPs within the MOF. Using CO₂ as a C1-feedstock, this combination allowed for the efficient transformation of a variety of diamine substrates into benzimidazoles. SION-105 could be easily recycled by washing with MeOH and reused multiple times without losing its identity and catalytic activity, highlighting the advantage of the MOF approach in FLP chem. In the experiment, the researchers used many compounds, for example, 7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6Category: imidazoles-derivatives).

7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Category: imidazoles-derivatives

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Effect of dielectric constant on estimation of properties of ionic liquids: an analysis of 1-alkyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide was written by Olmo, Lourdes del;Lage-Estebanez, Isabel;Lopez, Rafael;Garcia de la Vega, Jose M.. And the article was included in RSC Advances in 2015.Reference of 404001-48-5 This article mentions the following:

A series of different cationic structures based on 1-alkyl-3-methylimidazolium were combined with a single anion, bis(trifluoromethylsulfonyl)imide (C_nmimNTf₂, n = 1 to 12) for analyzing the quality of COSMO-RS based estimations For this purpose, we have studied the structure as well as the estimations of several properties of one ionic liquid (IL). These estimations are obtained from polarization charge distribution in which the IL is embedded. Special attention has been paid to the effect of the dielec. constant value in the predictions. For this purpose, polarization charge d. has been modeled using several values of dielec. constant, and properties have been estimated in each case. Thus, σ-profiles and, σ-potentials have been computed and used with COSMO-RS for estimating vapor pressure, as a function of temperature, as well as theor. values of vaporization enthalpy, d., and viscosity at 298.15 K. The influence of the length of the alkyl chain of ionic liquid in the estimation of these properties has also been tested. Finally, the results have been compared with exptl. data. In the experiment, the researchers used many compounds, for example, 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5Reference of 404001-48-5).

3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Reference of 404001-48-5

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Enzymatic Production of Biodiesel from Millettia pinnata Seed Oil in Ionic Liquids was written by Huang, Ze-Lin;Yang, Tao-Xiang;Huang, Jian-Zi;Yang, Zhen. And the article was included in BioEnergy Research in 2014.COA of Formula: C18H31F6N3O4S2 This article mentions the following:

Millettia pinnata seed oil has been identified as a promising sustainable feedstock for biodiesel production Oils extracted from the seeds grown in freshwater and seawater habitats showed no significant differences in their physicochem. properties. The enzymic methanolysis of the oil has been investigated in the ionic liquid (IL) [BMIm][PF₆] (1-butyl-3-methylimidazolium hexafluorophosphate) as compared to tert-butanol, catalyzed by Penicillium expansum lipase (PEL) and Candida antarctica lipase B (Novozym 435). Under optimal conditions, PEL induced much higher yields in the IL than in tert-butanol, while in the IL PEL-catalyzed conversions were higher than those catalyzed by Novozym 435. The catalytic processes were improved by recycling both the enzyme (Novozym 435) and the IL ([BMIm][PF₆]) and by searching for new enzymes and new ILs. The impact of ILs on biodiesel production has been discussed, and the interactions between the IL, the substrate, and the enzyme are believed to play an important role in governing the conversion. In the experiment, the researchers used many compounds, for example, 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5COA of Formula: C18H31F6N3O4S2).

3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).COA of Formula: C18H31F6N3O4S2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem