Month: February 2023

Hierarchically Crosslinked Gels Containing Hydrophobic Ionic Liquids towards Reliable Sensing Applications was written by Chen, Xia-Chao;Sun, Pei-Ru;Liu, Hong-Liang. And the article was included in Chinese Journal of Polymer Science in 2020.Formula: C18H31F6N3O4S2 This article mentions the following:

Human skin can function steadily regardless of surrounding circumstances (dry or wet), while it is still a challenge for artificial ionic skins, which tend to release solvents in dry air and leach electrolytes in wetted state. Herein, a series of hierarchically crosslinked ionogels containing hydrophobic ionic liquids (ILs) is fabricated by combining a crystalline fluorinated copolymer with hydrophobic ILs. With a reasonable combination of nonvolatility, transparency, stretchablility, and sensitivity, such ionogels can work as reliable sensors for real-time monitoring human motions and operate steadily in complex environments as human skin does, which can contribute to the development of durable sensing devices with a simple design. In the experiment, the researchers used many compounds, for example, 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5Formula: C18H31F6N3O4S2).

3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Formula: C18H31F6N3O4S2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

A Multiscale Simulation Study of Influence of Morphology on Ion Transport in Block Copolymeric Ionic Liquids was written by Zhang, Zidan;Krajniak, Jakub;Ganesan, Venkat. And the article was included in Macromolecules (Washington, DC, United States) in 2021.Synthetic Route of C9H15F6N2P This article mentions the following:

We present results of a multiscale simulation study involving coarse-graining and reverse-mapping steps probing at an atomistic resolution the influence of morphol. on ion transport in block copolymer polymeric ionic liquids We provide a detailed description of the multiscale simulation methodol. and then describe the results in the context of four microphase-separated morphologies: two lamella systems, a cylinder, and a gyroid morphol. For the framework adopted in this study (in which the total number of ions was maintained fixed), morphol. had little influence on the fraction of ions segregating to the interface and the coordination and hopping characteristics of such interfacially present ions. Such results manifested in anion mobilities being insensitive to the morphol. once the dimensionality of the morphol. was accounted for. Overall, our results are consistent with the hypothesis that the mobility of ions in such microphase-separated morphologies, after accounting for the dimensionality effects, can be roughly correlated to a linear superposition based on the fraction of bulk anions, which possess mobilities unperturbed from their values in the conducting homopolymers, and the interfacial anions, which exhibit much lower mobilities. In the experiment, the researchers used many compounds, for example, 1-Butyl-3-vinyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 915358-85-9Synthetic Route of C9H15F6N2P).

1-Butyl-3-vinyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 915358-85-9) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Synthetic Route of C9H15F6N2P

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Nano/microtribological properties of ultrathin functionalized imidazolium wear-resistant ionic liquid films on single crystal silicon was written by Mo, Yufei;Zhao, Wenjie;Zhu, Min;Bai, Mingwu. And the article was included in Tribology Letters in 2008.Computed Properties of C7H13ClN2 This article mentions the following:

Ionic liquids (ILs) are considered as a new kind of lubricant for micro/nanoelectromech. system (M/NEMS) due to their excellent thermal and elec. conductivity However, so far, only few reports have investigated the triboltribol. behavior of mol. thin films of various ILs. Evaluating the nanoscale tribol. performance of ILs when applied as a few nanometers-thick film on a substrate is a critical step for their application in MEMS/NEMS devices. To this end, four kinds of ionic liquid carrying Me, hydroxyl, nitrile, and carboxyl group were synthesized and these mol. thin films were prepared on single crystal silicon wafer by dip-coating method. Film thickness was determined by ellipsometric method. The chem. composition and morphol. were characterized by the means of multi-technique X-ray photoelectron spectrometric anal., and at. force microscopic (AFM) anal., resp. The nano- and microtribol. properties of the ionic liquid films were investigated. The morphologies of wear tracks of IL films were examined using a 3D non-contact interferometric microscope. The influence of temperature on friction and adhesion behavior at nanoscale, and the effect of sliding frequency and load on friction coefficient, load bearing capacity, and anti-wear durability at microscale were studied. Corresponding tribol. mechanisms of IL films were investigated by AFM and ball-on-plane microtribotester. Friction reduction, adhesion resistance, and durability of IL films were dependent on their cation chem. structures, wettability, and ambient environment. In the experiment, the researchers used many compounds, for example, 1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8Computed Properties of C7H13ClN2).

1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Computed Properties of C7H13ClN2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Cu-catalyzed amidation of halogenated imidazoles was written by Wang, Mo;Zhang, Zhenfeng;Xie, Fang;Zhang, Wanbin. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2014.Synthetic Route of C4H5BrN2 This article mentions the following:

An efficient methodol. involving the Cu-catalyzed amidation of halogenated imidazoles has been successfully developed. The amidated product of 5-bromo-1-alkylimidazole was further applied to the synthesis of a new chiral imidazole nucleophilic catalyst for the kinetic resolution of secondary alcs. In the experiment, the researchers used many compounds, for example, 4-Bromo-1-methylimidazole (cas: 25676-75-9Synthetic Route of C4H5BrN2).

4-Bromo-1-methylimidazole (cas: 25676-75-9) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Synthetic Route of C4H5BrN2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Amphiphilic multi-charged cyclodextrins and vitamin K co-assembly as a synergistic coagulant was written by Li, Pei-yu;Chen, Yong;Chen, Chang-hui;Liu, Yu. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2019.Computed Properties of C11H20N2 This article mentions the following:

Balancing and neutralizing heparin dosing after surgeries and hemodialysis treatment is of great importance in medical and clin. fields. In this study, a series of new amphiphilic multi-charged cyclodextrins (AMCD)s as anti-heparin coagulants were designed and synthesized. The AMCD assembly was capable of selective heparin binding through multivalent bonding and showed a better neutralizing effect towards both unfractionated heparin and low mol. weight heparin than protamine in plasma. Meanwhile, an AMCD and vitamin K (VK) co-assembly was prepared to realize heparin-responsive VK release and provide a novel VK deficiency treatment for hemodialysis patients. This AMCD-VK co-assembly for heparin neutralization & vitamin K supplementation synergistic coagulation represents a promising candidate as a clin. anti-heparin coagulant. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Computed Properties of C11H20N2).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Computed Properties of C11H20N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Two-step redox systems. XV. Vinylogous bibenzimidazoles, bibenzoxazoles, and bibenzothiazoles and their aza derivatives was written by Huenig, Siegfried;Scheutzow, Dieter;Schlaf, Helmut;Schott, Albrecht. And the article was included in Justus Liebigs Annalen der Chemie in 1974.Recommanded Product: 3012-80-4 This article mentions the following:

The bibenzimidazoles and bibenzothiazoles I [Z = (CH:CH)n, n = 1-3, X = NMe or S, A- = e.g. BF4-] were prepared by two-fold ring closure of 2-HXC6H4NHMe with R1CO(CH:CH)nCOR1 (R1 = Cl or Me2CHCH2OCO2). Similarly prepared were I [X = S, Z = CH2(CH:CH)nCH2, n = 0-2]. I (X = O, Z = CH2CH2) was obtained by quaternization of the base. I (X = NMe, O, or S; Z = CH:NN:CH) were prepared by reaction of the heterocyclic aldehydes or the corresponding nitrones with N2H4 followed by quaternization. Coupling the hydrazono compounds II with glyoxal gave the tetraaza analogs III. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde (cas: 3012-80-4Recommanded Product: 3012-80-4).

1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde (cas: 3012-80-4) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Recommanded Product: 3012-80-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synergy of ionic liquid and confinement in the design of supported palladium catalyst for efficient selective hydrogenation of acetylene was written by Wang, Qingtao;Xu, Yiqi;Zhou, Jing;Xu, Longyu;Yu, Lu;Jiang, Dahao;Lu, Chunshan;Pan, Zhiyan;Zhang, Qunfeng;Li, Xiaonian. And the article was included in Journal of Industrial and Engineering Chemistry (Amsterdam, Netherlands) in 2021.Related Products of 79917-89-8 This article mentions the following:

We present here a novel fabrication of highly effective supported Pd catalysts (Pd@S-1@IL) derived from Pd@S-1 core-shell material coated with ionic liquids (ILs), [Prmim][Cl], for the selective hydrogenation of acetylene. Catalytic testing on Pd@S-1@IL catalyst illustrated a remarkable selectivity towards semi-hydrogenation (over 90% for ethylene, irresp. of conversion level). Moreover, no indications of deactivation were observed after 800 h on stream even under relatively severe conditions. Detailed characterization indicated that the selectivity enhancement was ascribed to the filter effect along with electronic effect on the adsorption/desorption processes arising from the ionic liquids layer. The stability, which has ranked the top reported values over advanced Pd-based catalysts, is attributed to the confinement effect of Pd NPs within the supports thus restricting the migration of metals. The fabrication of core-shell architecture combined with the advantages of ionic liquid layer offers a promising guideline for efficient catalytic transfer of chem. resource. In the experiment, the researchers used many compounds, for example, 1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8Related Products of 79917-89-8).

1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Related Products of 79917-89-8

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Effectively catalytic hydrolysis of cellulose to glucose in the presence of pyrrolidonium-based acidic ionic liquids was written by Feng, Jianping;Liu, Min;Jia, Songyan;Gong, Yanyan;Song, Chunshan;Guo, Xinwen. And the article was included in Shiyou Xuebao, Shiyou Jiagong in 2012.Name: 1-Methyl-1H-imidazol-3-ium chloride This article mentions the following:

A series of acidic ionic liquids (methylimidazolium-based acidic ionic liquids and pyrrolidonium-based acidic ionic liquids) were synthesized and characterized. The cellulose hydrolysis into glucose, in which ionic liquid 1-butyl-3-methylimidazolium ([Bmim]Cl) was used as the solvent, in the presence of the synthesized acidic ionic liquids was studied systematically. The influences of water content, procedure of adding water, kinds of catalyst, catalyst dosage, reaction temperature and reaction time on the conversion of cellulose and yield of glucose were investigated. It was shown that pyrrolidonium-based acidic ionic liquids were better in catalyzing the hydrolysis of cellulose into glucose than methylimidazolium-based acidic ionic liquids Under the optimized reaction conditions, which were the reaction temperature of 110掳C, n(catalyst): (glucose unit in cellulose): n(H₂O) = 1:3:210, [Hnmp]CH₃SO₃ as catalyst, with the water addition of once per 10 min in 40 min, and the reaction time of 2 h, the glucose yield of cellulose hydrolysis was 68%. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Name: 1-Methyl-1H-imidazol-3-ium chloride).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Name: 1-Methyl-1H-imidazol-3-ium chloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Quantum chemical study on nitroimidazole, polynitroimidazole and their methyl derivatives was written by Su, Xinfang;Cheng, Xinlu;Meng, Chuanmin;Yuan, Xiaoli. And the article was included in Journal of Hazardous Materials in 2009.Recommanded Product: 3034-41-1 This article mentions the following:

The insensitive explosive candidates, nitroimidazoles, polynitroimidazoles and their Me derivatives, are studied using d. functional theory (DFT). The homolytic bond dissociation energies (BDEs) corresponding to -NO₂ group removal from C or N site on imidazole ring were calculated at B3P86/6-311G** level, and the weakest bond has been determined A correlation is developed between impact sensitivity h₅₀ and the ratio (BDE/E) of the weakest bond BDE to the total energy E, and we extrapolate this relation to predict the impact sensitivities for compounds where experiments are not available. It is found that most of the title compounds are insensitive towards impact stimuli with their h₅₀ >60.0 cm. Heats of formation (HOFs) for the 21 title compounds at 298 K in gas are also determined both at B3LYP/6-311G** and B3P86/6-311G** levels using isodesmic work reactions. The calculated BDEs and HOFs consistently indicate that C-nitro-substituted imidazole is more stable than the corresponding N-substituted one, and the introduction of Me on C increases the stability whereas the Me attached to N atom decreases the stability. In the experiment, the researchers used many compounds, for example, 1-Methyl-4-nitroimidazole (cas: 3034-41-1Recommanded Product: 3034-41-1).

1-Methyl-4-nitroimidazole (cas: 3034-41-1) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Recommanded Product: 3034-41-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Chemiluminescent intensities from substituted lophines was written by Philbrook, G. E.;Maxwell, M. A.. And the article was included in Tetrahedron Letters in 1964.Formula: C22H16N2O2 This article mentions the following:

Chemiluminescent intensities of 14 lophine derivatives, substituted in the 3 and (or) 4 position(s) of the 2-phenyl group, were determined in 7:3 Me₂SO-H₂O solution, N in NaOH. O was passed through the solution continuously. The intensity of emission passed through a maximum (I_maximum) after 1-2 min. and then declined. A Hammett plot of I_maximum/I₀ against 蟽 values was reported, where I₀ is the intensity maximum for lophine (I). The observed slope, -1.96 卤 0.06, compares with a value of -1.16 卤 0.06 obtained when similar plots were constructed with 蟽⁺ values (Brown and Okamoto, CA 53, 9120f). The emission intensity was a linear function of concentration for I, and the 4-carboxy, 4-MeO, 3,4-dimethoxy, and 4-Cl derivatives over the concentration range 3 脳 10^-3 to 3 脳 10^-5 M. The chemiluminescent maximum for all the compounds, except the nitro derivative, fell at 5300 A. It appeared that the chemiluminescent processes in all cases examined yield the same mol. fragment. Probably the substituent present in the original derivative was not present in this fragment. In the experiment, the researchers used many compounds, for example, 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoic acid (cas: 5496-35-5Formula: C22H16N2O2).

4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoic acid (cas: 5496-35-5) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Formula: C22H16N2O2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem