Synthesis of imidazo[1,2-a]benzimidazole and imidazolino-[1,2-a]benzimidazole derivatives was written by Simonov, A. M.;Kochergin, P. M.. And the article was included in Khimiya Geterotsiklicheskikh Soedinenii in 1965.Application In Synthesis of 2,3-Dihydro-1H-benzo[d]imidazo[1,2-a]imidazole This article mentions the following:
Reaction of 1-alkyl-2-aminobenzimidazoles with α-halo ketones and α-halo alcs. gave the corresponding 1,3-disubstituted 2-iminobenzimidazolines, which under the action of dehydrating agents or by heating with mineral or organic acids lost H2O and gave derivatives of [1,2-a]benzimidazole (I) or the corresponding 2,3-dihydro compounds Thus were obtained: 1-ethyl-3-phenacyl-2-iminobenzimidazoline, m. 120.5° (aqueous MeOH) [hydrobromide m. 2222.5° (decomposition, MeOH)]; 2-phenyl-9-ethylimidazo[1,2-a]benzimidazole, m. 93-3.5° (aqueous EtOH) [picrate m. 238-40° (decomposition, EtOH)]; 1-ethyl-3-(β-hydroxyethyl)-2-iminobenzimidazoline, m. 122.5-23° (C2H4Cl2) [hydrobromide m. 226.5-27° (decomposition, EtOH); picrate m. 182-3° (H2O)]; and 9-ethylimidazolino[1,2-a]benzimidazole [picrate m. 267-8° (decomposition, AcOH)]. In the experiment, the researchers used many compounds, for example, 2,3-Dihydro-1H-benzo[d]imidazo[1,2-a]imidazole (cas: 24134-26-7Application In Synthesis of 2,3-Dihydro-1H-benzo[d]imidazo[1,2-a]imidazole).
2,3-Dihydro-1H-benzo[d]imidazo[1,2-a]imidazole (cas: 24134-26-7) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Application In Synthesis of 2,3-Dihydro-1H-benzo[d]imidazo[1,2-a]imidazole
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem