S-Adenosylhomocysteine Analogue of a Fairy Chemical, Imidazole-4-carboxamide, as its Metabolite in Rice and Yeast and Synthetic Investigations of Related Compounds was written by Ouchi, Hitoshi;Namiki, Takuya;Iwamoto, Kenji;Matsuzaki, Nobuo;Inai, Makoto;Kotajima, Mihaya;Wu, Jing;Choi, Jae-Hoon;Kimura, Yoko;Hirai, Hirofumi;Xie, Xiaonan;Kawagishi, Hirokazu;Kan, Toshiyuki. And the article was included in Journal of Natural Products in 2021.Application In Synthesis of 1H-Imidazole-4-carboxamide This article mentions the following:
During the course of our investigations of fairy chems. (FCs), we found S-ICAr-H I, as a metabolite of imidazole-4-carboxamide (ICA) in rice and yeast (Saccharomyces cerevisiae). In order to determine its absolute configuration, an efficient synthetic method of I was developed. This synthetic strategy was applicable to the preparation of analogs of I. In the experiment, the researchers used many compounds, for example, 1H-Imidazole-4-carboxamide (cas: 26832-08-6Application In Synthesis of 1H-Imidazole-4-carboxamide).
1H-Imidazole-4-carboxamide (cas: 26832-08-6) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Application In Synthesis of 1H-Imidazole-4-carboxamide
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem