An efficient method for the preparation of 4(5)-cyanoimidazoles was written by Leone-Bay, Andrea;Glaser, Laurel. And the article was included in Synthetic Communications in 1987.SDS of cas: 26832-08-6 This article mentions the following:
Imidazolecarboxylates I (R1 = H, alkyl, Ph; R2 = H, Br; R3 = H, Me) were amidated to carboxamides II, which were heated with PhP(O)Cl2 to give III. In the experiment, the researchers used many compounds, for example, 1H-Imidazole-4-carboxamide (cas: 26832-08-6SDS of cas: 26832-08-6).
1H-Imidazole-4-carboxamide (cas: 26832-08-6) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.SDS of cas: 26832-08-6
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem