Electric Literature of 4856-97-7, These common heterocyclic compound, 4856-97-7, name is (1H-Benzoimidazol-2-yl)methanol, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
A mixture of NiCl2*6H2O (0.238 g, 1 mmol), HL1 (0.074 g,0.5 mmol), acetonitrile (4 mL) and ethanol (4 mL), with a pHadjusted to 7.5 by addition of triethylamine, was poured into aTeflon-lined autoclave (15 mL) and then heated at 160 ¡ãC for 3 days. Green crystals of 1 were collected by filtration, washed with ethanol and dried in air. Phase pure crystals of 1 were obtained by manual separation (yield: 89.5 mg, ca. 63.4percent based onthe HL1 ligand). Anal. Calc. for 1: C40H40Cl4N12Ni4O4(Mr = 1129.40), Calc.: C, 42.54; H, 3.57; N, 14.88. Found: C, 42.51;H, 3.59; N, 14.91percent. IR data for 1 (KBr, cm1): 3425 s, 1274 m,1458 s, 1069 s, 1280 m, 600 m, 467 m.
The synthetic route of 4856-97-7 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Yang, Li; Zhang, Shu-Hua; Wang, Wei; Guo, Jing-Jing; Huang, Qiu Ping; Zhao, Ru-Xia; Zhang, Chun-Lian; Muller, Gilles; Polyhedron; vol. 74; (2014); p. 49 – 56;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem