Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 29043-48-9, name is 2-Methyl-1H-benzoimidazol-5-ylamine, This compound has unique chemical properties. The synthetic route is as follows., category: imidazoles-derivatives
Example No. 289Preparation of 6- (7- ( (2-methyl -lH-benzo [d] imidazol-5- yl)amino) -IH-pyrazolo [4, 3-d] pyrimidin- 5 -yl) -2H- benzo [b] [1 , 4] oxazin-3 (4H) -one6- (7-chloro-2- (4-methoxybenzyl) -2H-pyrazolo [4 , 3 -d] pyrimidin- 5- yl) -2H-benzo [b] [1, 4] oxazin-3 (4H) -one (0.16 mmol) and 2-methyl- lH-benzo [d] imidazol-5-amine (0.3 mmol 2 eq. , ) were suspended in MeOH (dry, 3mL) in a microwave vial (2-5mL) , HC1 in dioxane (4M, 3 drops) was added. The reaction mixture was irradiated in a microwave reactor for 5 min at 140 C. The reaction mixture was evaporated and used without further purification. The residue was dissolved in TFA (3mL) . The reaction mixture was irradiated in a microwave reactor for 5 min at 140C. The reaction mixture was concentrated and purified by semi- preparative HPLC-MS and freeze dried from water/t-BuOH 4/1. exact mass: 412.1584 g/molHPLC-MS: analytical method Drt: 3.81 min – found mass: 413 (m/z+H)
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 29043-48-9.
Reference:
Patent; ORIGENIS GMBH; ALMSTETTER, Michael; THORMANN, Michael; TREML, Andreas; TRAUBE, Nadine; WO2012/143144; (2012); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem