In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 3034-38-6, name is 5-Nitro-1H-imidazole belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. Formula: C3H3N3O2
To a solution of 4-nitro- 1 H-imidazole (5.0 g, 44 mmol, 1 eq.) in ACN (50 ml) was added K2C03 (9.17 g, 66 mmol). Methyl iodide (7.53 g, 53 mmol, 3.30 ml) was added slowly to the mixture at rt, then the mixture was warmed to 60 C for 14 h. The solvent was removed under reduced pressure, then the residue was diluted with water (30 ml), extracted with DCM (5 x 30 ml) and the combined organic layers dried over Na2S04. The organic phase was concentrated in vacuo to give the title compound as a yellow solid. ‘H NMR (400 MHz, DMSO-de) d = 8.35 (s, 1H), 7.80 (s, 1H), 3.75 (s, 3H).
The synthetic route of 3034-38-6 has been constantly updated, and we look forward to future research findings.