Introduction of a new synthetic route about 13750-81-7

The chemical industry reduces the impact on the environment during synthesis 1-Methyl-1H-imidazole-2-carbaldehyde. I believe this compound will play a more active role in future production and life.

Application of 13750-81-7, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 13750-81-7, name is 1-Methyl-1H-imidazole-2-carbaldehyde, This compound has unique chemical properties. The synthetic route is as follows.

First, 1-methylimidazole-2-carboxaldehyde was prepared according to the literature procedure[23]. The synthesis procedure then followed that of Im2COOH (1b) above and the yield was also quantitative after the removal of water under high vacuum (no washing with diethylether/water was necessary). Note: heating causes decarboxylation. Yield: 100%. Mp=99-101C. deltaH (400MHz, D2O): 7.42, 7.39 (2H, s, Im-H) and 4.08ppm (3H, s, NCH3); deltaC (400MHz, D2O): 158.67, 139.68, 125.83, 118.46, 36.73ppm. IR nu (KBr): 3347(m) 3119(m), 2663(w), 1641(s), 1683(m), 1507(s), 1449(m), 1388(s), 1338(s), 1285(s), 1173(m), 1123(s), 961(m) 910(m), 776(s), 685(s) cm-1. Anal. Calc. for C5H8N2O3 (144.12); C, 41.67; H, 5.59; N, 19.44%. Found: C, 41.28; H, 5.23; N, 19.12%.

The chemical industry reduces the impact on the environment during synthesis 1-Methyl-1H-imidazole-2-carbaldehyde. I believe this compound will play a more active role in future production and life.

Reference:
Article; Gundhla, Isaac Z.; Walmsley, Ryan S.; Ugirinema, Vital; Mnonopi, Nandipha O.; Hosten, Eric; Betz, Richard; Frost, Carminita L.; Tshentu, Zenixole R.; Journal of Inorganic Biochemistry; vol. 145; (2015); p. 11 – 18;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem