Synthetic Route of 10351-75-4, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 10351-75-4, name is 1H-Benzo[d]imidazole-5,6-dicarboxylic acid, This compound has unique chemical properties. The synthetic route is as follows.
2.2.1 H24-DPBB A mixture of benzimidazole-5,6-dicarboxylic acid (2.0616 g, 10 mmol) and 4-aminobenzoic acid (1.3714 g, 10 mmol) in 30 ml DMF was heated at 135 C for 10 h, then filtrated. The product was washed several time with hot DMF and EtOH, then dried in air. Yield: 70%. Element analysis (%): Anal. Calc. for C16H9N3O4: C 62.54, H 2.95, N 13.68. Found: C 62.55, H 2.91, N 13.65%. IR (KBr pellet, cm-1): 3340(m), 3050(s), 1770(m), 1713(vs), 1605(m), 1509(m), 1371(vs), 1264(vs), 1118(m), 865(s), 835(s), 610(s). Negative ESI-MS (m/z): 305.98 (H24-DPBB-H+). 1H NMR (DMSO-d6): delta: 7.630 (J = 4.8 Hz, d, 2H, Ph-H), 8.097 (J = 1.2 Hz, d, 2H, Ph-H), 8.114 (s, 1H, Ph-H), 8.208 (s, 1H, Ph-H), 8.602 (s, 1H, Im-H), 13.320 (s, 1H, COOH). Melting points: above 300 C.
The chemical industry reduces the impact on the environment during synthesis 1H-Benzo[d]imidazole-5,6-dicarboxylic acid. I believe this compound will play a more active role in future production and life.
Reference:
Article; Yang, Jing-Si; Zhu, Jiang; Liu, Rui-Bin; Ni, Jun; Chang, Zhi-Duo; Hu, Tao; Zhang, Jian-Jun; Meng, Chang-Gong; Inorganica Chimica Acta; vol. 394; (2013); p. 117 – 126;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem