In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2620-76-0, name is 2-(4-Bromophenyl)-1-phenyl-1H-benzoimidazole belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. Computed Properties of C19H13BrN2
[0076] l-phenyl-2-(4-(4,4,5,5-tetramethyl-l,3,2-dioxaborolan-2-yl)phenyl)- lH-benzo[d]imidazole (3): A mixture of compound (2) (0.70 g, 2 mmol), bis(pinacolate)diborane (0.533g, 2.1 mmol), Pd(dppf)Cl2 (0.060 g, 0.08 mmol) and anhydrous potassium acetate (0.393 g, 4mmol) in 1,4-dioxane (20 mL) was heated at about 80 C under argon overnight. After cooling to room temperature, the whole was diluted with ethyl acetate (~80 mL) then filtered. The solution was absorbed on silica gel, then purified by column chromatography (hexanes/ethyl acetate 5: 1 to 3:1) to give a white solid (0.64 g, in 81% yield).
The synthetic route of 2620-76-0 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; NITTO DENKO CORPORATION; ZHENG, Shijun; SISK, David, T.; HARDING, Brett, T.; CAYAS, Jensen; LI, Sheng; MOCHIZUKI, Amane; CHAE, Hyun, Sik; KHAN, Sazzadur, Rahman; MA, Liping; BOTTGER, Rebecca; WO2011/34967; (2011); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem