Shaikh, Irfan N.;Bagwan, Umar Farooq;Hunagund, Shirajahammad M.;Shaikh, Imran N.;Afzal, Mohammed published 《Cu-catalyzed Rapid Synthesis of Novel Fluorinated Indole Derivatives Under Microwave Irradiation》 in 2018. The article was appeared in 《Chemistry Africa》. They have made some progress in their research.Product Details of 5805-39-0 The article mentions the following:
Herein, a simple microwave-assisted synthesis of novel fluorinated indole derivatives I [R = (1H-benzimidazol-2-yl)phenyl, 6-chloro-7H-purin-2-yl, 3-amino-2,2-dimethyl-3-phenylpropyl, etc.] have been developed by the reaction of 5-fluoroindoline-2,3-dione with various anilines RNH2. The reaction could be conducted using readily available substrates within short periods of 9-15 min under microwave irradiation with good to excellent yields of the product (64-92%). This approach exploits the synthetic potential of microwave irradiation and copper dipyridine dichloride (CuPy2Cl2) combination and offers many advantages such as full reaction control, excellent product yields, shorter reaction time, eco-friendly procedure and rapid feedback. The experimental procedure involved many compounds, such as 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) .
2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Product Details of 5805-39-0) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.
Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem