《Access to dihydropyrano[3,2-b]pyrrol-5-ones skeletons by N-heterocyclic carbene-catalyzed [3+3] annulations》 was published in Chemical Communications (Cambridge, United Kingdom) in 2020. These research results belong to Wu, Ya-Tong; Zhang, Rui; Duan, Xiao-Yong; Yu, Hai-Fei; Sun, Bo-Yu; Qi, Jing. Application In Synthesis of 1,3-Dimesityl-1H-imidazol-3-ium chloride The article mentions the following:
A novel and efficient NHC-catalyzed [3+3] annulation of enals, e.g., RCH:CHCHO (R = n-hexyl, cyclohexyl, Ph, furan-2-yl, etc.), with pyrrol-4-ones I (R1 = Me, Et, t-Bu; R2 = EtO2C, Boc) was developed, thus providing the dihydropyrano[3,2-b]pyrrol-5-one core structures, e.g., II, with broad scope and good to excellent enantioselectivities. Notably, this strategy could also be expanded to the synthesis of axially chiral compounds and polysubstituted indoles. In addition to this study using 1,3-Dimesityl-1H-imidazol-3-ium chloride, there are many other studies that have used 1,3-Dimesityl-1H-imidazol-3-ium chloride(cas: 141556-45-8Application In Synthesis of 1,3-Dimesityl-1H-imidazol-3-ium chloride) was used in this study.
1,3-Dimesityl-1H-imidazol-3-ium chloride(cas: 141556-45-8) is a ligand for arylation of aldehydes and for carbene catalyzed intermolecular arylation of C-H bonds. It is used as a phosphine-free ligand in various metal-catalyzed coupling reactions, often with advantageous results in difficult cases.Application In Synthesis of 1,3-Dimesityl-1H-imidazol-3-ium chloride
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem