In 2017,Abdellattif, Magda H.; Eissa, A. M. F.; Mohamed, H. M. published 《Synthesis of anionic surface active agents containing heterocyclic moiety from long chain fatty alcohols》.Journal of Advances in Chemistry published the findings.Safety of 1H-Imidazol-2-amine The information in the text is summarized as follows:
A series of novel groups of anionic surface active agent were synthesized. Synthesis of these surfactants via the reaction of long chain fatty alcs. (octyl, decyl and dodecyl) with maleic anhydride to give monoester. The monoester chloride reacted with amino derivatives of heterocyclic rings followed by addition of NaHSO3. The surface tension, interfacial tension; Kraft point, emulsifying and wetting power were evaluated. Stability to hydrolysis, biodegradability and biol. activities were measured. A comparison studies between the chem. structures and the results were done. After reading the article, we found that the author used 1H-Imidazol-2-amine(cas: 7720-39-0Safety of 1H-Imidazol-2-amine)
1H-Imidazol-2-amine(cas: 7720-39-0) belongs to anime. To avoid the problem of multiple alkylation, methods have been devised for “blocking” substitution so that only one alkyl group is introduced. The Gabriel synthesis is one such method; it utilizes phthalimide, C6H4(CO)2NH, whose one acidic hydrogen atom has been removed upon the addition of a base such as KOH to form a salt.Safety of 1H-Imidazol-2-amine
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem