Kirk, Kenneth L.’s team published research in Journal of Organic Chemistry in 1978 | CAS: 16681-56-4

2-Bromo-1H-imidazole(cas: 16681-56-4) is a member of imidazole. Its exclusive structural characteristics with enviable electron-rich features are favorable for imidazole-based fused heterocycles to bind efficiently with an array of enzymes and receptors in biological systems through various weak interactions like hydrogen bonds, ion-dipole, cation-π, π-π stacking, coordination, Van der Waals forces, hydrophobic effects, etc., and therefore they demonstrate widespread bioactivities. HPLC of Formula: 16681-56-4

In 1978,Kirk, Kenneth L. published 《Facile synthesis of 2-substituted imidazoles》.Journal of Organic Chemistry published the findings.HPLC of Formula: 16681-56-4 The information in the text is summarized as follows:

Imidazoles I (R = H, R1 = Br, iodo, Cl, Me, CO2Et, CHO, NH2) were prepared by treating 1-trityl-2-lithioimidazole (I, R = Ph3C, R1 = Li) with an appropriate electrophile followed by detritylation with acid. The experimental process involved the reaction of 2-Bromo-1H-imidazole(cas: 16681-56-4HPLC of Formula: 16681-56-4)

2-Bromo-1H-imidazole(cas: 16681-56-4) is a member of imidazole. Its exclusive structural characteristics with enviable electron-rich features are favorable for imidazole-based fused heterocycles to bind efficiently with an array of enzymes and receptors in biological systems through various weak interactions like hydrogen bonds, ion-dipole, cation-π, π-π stacking, coordination, Van der Waals forces, hydrophobic effects, etc., and therefore they demonstrate widespread bioactivities. HPLC of Formula: 16681-56-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem