Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Related Products of 10111-08-7.
Singh, Ekta;Matada, Gurubasavaraja Swamy Purawarga research published 《 Chemical features responsible for the antioxidant property in 7-azaindoles and related compounds》, the research content is summarized as follows. The pro-oxidant mols. are reactive towards the cell organelles due to instability in their electronic composition Thus, pro-oxidants interact with and cause damages to cell organelles. This damage can be prevented by antioxidant mols. as they neutralize the pro-oxidants and render them harmless. The ability of mols. to act as an antioxidant is exhibited by its chem. feature. Alpha tocopherol and its analogs are well established antioxidants. The antioxidants can be designed based on the structure of alpha tocopherol. Some research articles have compared the antioxidant properties of alpha tocopherol and small mols. with different heterocylic rings. In continuation to the development of small antioxidant mols. azaindole analogs have also been compared with alpha tocopherol. Azaindoles are a novel class of compounds that can be developed as antioxidant mols. based on their similarity with heterocyclic rings present in reported antioxidants. In the current research we have studied some azaindole related compounds and their antioxidant properties. The objective of this study is to study some 7-azaindole related compounds as antioxidants. In this research work, small substituted azaindoles and related structures have been studied for their antioxidant properties by DPPH assay method. The structure with Ketone and double bond functional group show antioxidant property in DPPHA assay. The presence of chlorine on aromatic ring increases the antioxidant property of azaindoles. Azaindole scaffold can be used to design and develop novel antioxidant mols.
10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Related Products of 10111-08-7
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem