On January 31, 2004, El-Ghoul, W.; Zabady, M.; Saleh, I. published an article.Safety of N-(2-Bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride The title of the article was Total intravenous anaesthesia in donkeys (Equus asinus): comparison of anaesthetic and cardiorespiratory effects of four anaesthetic drug combinations. And the article contained the following:
Twenty eight mature donkeys subjected to elective surgery were randomly assigned to four groups of 7 donkeys. After premedication with 80 渭g/kg of romifidine and 0.4 mg/kg of diazepam administered i.v. anesthesia was induced either with 5 mg/kg IV thiopental sodium (group I), 2.2 mg/kg IV ketamine (group II), 3 mg/kg IV propofol (group III) or 5g/50kg IV chloral hydrate (group IV). Anesthesia was maintained with continuous i.v. infusion using a mixture of 1 g thiopental/25 g guaifenesin/30 mg romifidine in 500 mL 5% dextrose (group I), 500 mg ketamine/25 g guaifenesin/30 mg romifidine in 500 mL 5% dextrose (group II), 400 mg propofol/25 g guaifenesin/30 mg romifidine in 500 mL 5% dextrose (group III) or 25g chloral hydrate, 25 g guaifenesin/30 mg romifidine in 500 mL 5% dextrose (group IV). The anesthetic and cardiorespiratory responses to the four injectable anesthetic combinations are reported. The results indicated that the four anesthetic combinations could be used as a safe method of total i.v. anesthesia for short and prolonged surgical procedures under field conditions in donkeys. The experimental process involved the reaction of N-(2-Bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride(cas: 65896-14-2).Safety of N-(2-Bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride
The Article related to intravenous anesthesia drug combination cardiorespiratory effect hematol, Pharmacology: Effects Of Nervous System- and Behavior-Affecting Drugs and Neuromuscular Agents and other aspects.Safety of N-(2-Bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride
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Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem