On May 5, 2022, Slassi, Siham; Aarjane, Mohammed; Amine, Amina published an article.Synthetic Route of 5036-48-6 The title of the article was Synthesis, spectroscopic characterization (FT-IR, NMR, UV-Vis), DFT study, antibacterial and antioxidant in-vitro investigations of 4,6-bis((E)-1-((3-(1H-imidazol-1-yl)propyl)imino)ethyl)benzene-1,3-diol. And the article contained the following:
A new bis-Schiff base, I derived from N-(3-aminopropyl)imidazole and 4,6-diacetylresorcinol was obtained. The bis Schiff base I was characterized through mass spectrometry, elemental anal., IR, UV-Vis, 1H and 13C NMR spectroscopy. The B3LYP method was used to calculate the optimized structure of the mol. through d. functional of theory (DFT) using the 6-31G (d, p) basis set. The 1H and 13C NMR chem. shifts with respect to TMS were calculated using the (GIAO) method in DMSO-d6 and compared with the exptl. data. In addition, the frontier MOs, electronic properties and the mol. electrostatic potential (MEP) of RS were investigated using DFT calculations The compound showed significant antibacterial activity against Staphylococcus aureus. The DPPH free radical scavenging assay was used to evaluate the antioxidant activity. The effective concentration (EC50) showed that the compound has a good antioxidant activity. The experimental process involved the reaction of N-(3-Aminopropyl)-imidazole(cas: 5036-48-6).Synthetic Route of 5036-48-6
The Article related to bis imidazolyl propyl imino ethyl benzenediol preparation schiff base, antibacterial antioxidant surface electrostatic potential, Heterocyclic Compounds (More Than One Hetero Atom): Imidazoles and other aspects.Synthetic Route of 5036-48-6
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem