Bodke, Yadav D. published the artcileSynthesis and biological evaluation of imidazo pyridine derivatives containing morpholine nucleus, Related Products of imidazoles-derivatives, the main research area is phenylimidazopyridine morpholinylmethyl preparation antioxidant antifungal antibacterial.
A series of substituted 3-(morpholin-4-ylmethyl)-2-phenylimidazo[1,2-a]pyridine derivatives I (R1 = H, Br, CH3; R2 = H, OCH2C6H5; R3 = Cl, Br, NO2, CN; R4 = H, Cl) were synthesized. The title compounds I were synthesized by the Mannich reaction of imidazo[1,2-a]pyridines derivatives II, morpholine and formaldehyde with catalytic amount of acetic acid at reflux temperature The synthesized compounds I were screened for the antimicrobial and antioxidant activities. From antimicrobial activity results it was found that compounds I (R1 = Br; R2 = H; R3 = Br, CN; R4 = H) displayed very good antibacterial against Staphylococcus aureus and the compound I (R1 = Br; R2 = H; R3 = Br; R4 = H) showed very good antifungal activity against Pseudomonas aeruginosa. Compounds I (R1 = H, CH3; R2 = H, OCH2C6H5; R3 = Cl, CN; R4 = H, Cl) showed promising free radical scavenging activity.
Heterocyclic Letters published new progress about Alkyl aryl ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 1023-01-4 belongs to class imidazoles-derivatives, name is 2-(4-Bromophenyl)-6-methylimidazo[1,2-a]pyridine, and the molecular formula is C14H11BrN2, Related Products of imidazoles-derivatives.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem