Thomas, Andrew P. published the artcileNew nonpeptide angiotensin II receptor antagonists. 1. Synthesis, biological properties and structure-activity relationships of 2-alkylbenzimidazole derivatives, Synthetic Route of 79047-41-9, the publication is Journal of Medicinal Chemistry (1992), 35(5), 877-85, database is CAplus and MEDLINE.
Based on 2-[4-{2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-ylmethyl}phenyl]benzoic acid, a known angiotensin II receptor antagonist, a series of 1H-benzimidazol-1-yl analogs and 4-[(2-alkyl-1H-benzimidazol-1-yl)methyl]benzoic acids (I, R1 = alkyl; R2 = H, Cl, F, OMe, NO2; R3 = H, Br, Cl, F, Me, OMe) were prepared The antihypertensive structure-activity relationship of these benzimidazolyl derivatives and some rigid analogs, such as 2-(3-butyl-1-chloro-5H,11H-imidazo[5,1-c][1,4]benzoxazepin-8-yl)benzoic acid (II), was determined
Journal of Medicinal Chemistry published new progress about 79047-41-9. 79047-41-9 belongs to imidazoles-derivatives, auxiliary class Imidazole,Chloride,Alcohol, name is (2-Butyl-4-chloro-1H-imidazol-5-yl)methanol, and the molecular formula is C3H9ClOS, Synthetic Route of 79047-41-9.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem