Amrutkar, Sunil V.’s team published research in International Journal of Pharmacy and Pharmaceutical Sciences in 2 | CAS: 4760-35-4

International Journal of Pharmacy and Pharmaceutical Sciences published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C9H9ClN2, Computed Properties of 4760-35-4.

Amrutkar, Sunil V. published the artcileSynthesis and antifungal activity of 1-alkyl/H-2-[(4-alkyl/aryl-piperazin-1-yl)-methyl]-benzimidazole derivatives, Computed Properties of 4760-35-4, the publication is International Journal of Pharmacy and Pharmaceutical Sciences (2010), 2(2), 84-92, database is CAplus.

Substituted benzimidazoles were condensed with various substituted piperazine to synthesize a library of benzimidazole derivatives Thus, 2-(chloromethyl)benzimidazoles were prepared from appropriate 1,2-phenylenediamines by boiling for 8 h with ClCH2CO2H in concentrated HCl. Subsequent condensation with piperazines was achieved by boiling in dioxane with Et3N as base. The antifungal activity of the synthesized compounds was studied by disk diffusion against Candida albicans using ketoconazole as reference standard The compound showed antifungal activity comparable to ketoconazole.

International Journal of Pharmacy and Pharmaceutical Sciences published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C9H9ClN2, Computed Properties of 4760-35-4.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem