Abdellatif, Khaled R. A.’s team published research in Organic Chemistry: An Indian Journal in 9 | CAS: 4760-35-4

Organic Chemistry: An Indian Journal published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C9H9ClN2, Application of 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole.

Abdellatif, Khaled R. A. published the artcileSynthesis and antimicrobial activity of novel 2-substituted-1H-benzimidazole derivatives, Application of 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, the publication is Organic Chemistry: An Indian Journal (2013), 9(3), 115-120, database is CAplus.

The reaction of chloromethyl-1-methyl-1H-benzimidazole with ethyl-4-aminobenzoate yielded the ester 2 which upon hydrazinolysis resulted in [(1-methyl-1H-benzimidazol-2-ylmethyl)amino]benzohydrazide. Condensation of [(1-methyl-1H-benzimidazol-2-ylmethyl)amino]benzohydrazide with 2-nitrobenzaldehyde afforded the arylidene derivative which was cyclized to thiazolidinone derivative Substituted benzamide and oxadiazole derivative were prepared via reacting [(1-methyl-1H-benzimidazol-2-ylmethyl)amino]benzohydrazide with phthalic anhydride and benzoic acid, resp. Reaction of [(1-methyl-1H-benzimidazol-2-ylmethyl)amino]benzohydrazide with 4-chlorophenyl isocyanate and Et isothiocyanate gave the corresponding semicarbazide and thiosemicarbazide. The thiosemicarbazide was cyclized to triazole and thiadiazole derivatives Also, reacting thiosemicarbazide with both chloroacetic acid and maleic anhydride afforded thiazolidinone derivatives The prepared compounds were evaluated for in vitro antimicrobial activity using ciprofloxacin and triflucan as standard references

Organic Chemistry: An Indian Journal published new progress about 4760-35-4. 4760-35-4 belongs to imidazoles-derivatives, auxiliary class Chloride,Benzimidazole, name is 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole, and the molecular formula is C9H9ClN2, Application of 2-(Chloromethyl)-1-methyl-1H-benzo[d]imidazole.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem