Synthesis of diethyl maleate catalyzed by acid functionalized ionic liquids was written by Yu, Dan;Guo, Hongyun. And the article was included in Gongye Cuihua in 2009.Reference of 478935-29-4 The following contents are mentioned in the article:
Di-Et maleate was obtained by a reaction of maleic anhydride and anhydrous ethanol in the presence of an ionic liquid [i.e., TEAPS sulfate, N,N,N-triethyl-3-sulfo-1-propanaminium sulfate (1:1)]. Factors influencing the product formation were confirmed and the above-mentioned Di-Et maleate [i.e., (2Z)-2-butenedioic acid 1,4-di-Et ester, 99% yield] was obtained under the following reaction conditions : n(maleic anhydride) : n(ethanol) = 1:4, dosage of ionic liquid = 20% (wt) of maleic anhydride, cyclohexane as water carrier, 115°, reflux and water segregation for 4 h. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Reference of 478935-29-4).
1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Reference of 478935-29-4
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem