Synthesis and properties of imidazolium-derived biocidals was written by Li, Bingzhen;Li, Yihe;Zhang, Zhe;Xiao, Hua;Jiang, Zhenhua;Li, Gong Yi;Ahn, Kwang-Duk. And the article was included in Advanced Materials Research (Durnten-Zurich, Switzerland) in 2013.Category: imidazoles-derivatives This article mentions the following:
Synthesis and antibacterial activity evaluation of 1-alkyl-3-(4-vinylbenzyl)imidazolium chlorides (alkyl = Me, n-Bu, n-C6H13, n-C8H17, n-C12H25) with hydrophobic alkyl substituents are reported. In antibacterial activity study of these imidazolium salts by minimal inhibitory concentrations (MICs) on E. coli., the dodecyl-substituted product showed promising antibacterial activity with MICs at 2.4 μg/mL. It was found that the MIC value of the synthesized imidazole derivatives increased as the number of alkyl substituent carbons increased up to 12 carbons. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Category: imidazoles-derivatives).
1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Category: imidazoles-derivatives
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem