Visible light mediated C-H trifluoromethylation of (hetero)arenes was written by Xiao, Fang;Lin, Jin-Hong;Hao, Fei;Zheng, Xing;Guo, Yu;Xiao, Ji-Chang. And the article was included in Organic Chemistry Frontiers in 2022.Formula: C7H9N3O4 This article mentions the following:
A protocol for visible light mediated C-H trifluoromethylation of unactivated (hetero)arenes under blue LED irradiation has been developed. The reaction enables the rapid construction of a range of CF3-containing (hetero)arenes in moderate to high yields from the readily accessible trifluoromethylsulfonyl-pyridinium salt (TFSP). This protocol is also suitable for nitrogen-containing aromatic heterocycles, which are potentially useful in medicinal chem. In the experiment, the researchers used many compounds, for example, Ethyl 1-methyl-4-nitro-1H-imidazole-2-carboxylate (cas: 109012-23-9Formula: C7H9N3O4).
Ethyl 1-methyl-4-nitro-1H-imidazole-2-carboxylate (cas: 109012-23-9) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Formula: C7H9N3O4
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem