Synthesis and pharmacological activity of amides of 2,3-dihydroimidazo- and 2,3,4,10-tetrahydropyrimido[1,2-a]benzimidazolyl-N-acetic acids was written by Anisimova, V. A.;Spasov, A. A.;Kosolapov, V. A.;Tolpygin, I. E.;Tibir’kova, E. V.;Salaznikova, O. A.;Kuznetsova, V. A.;Gurova, N. A.;Lenskaya, K. V.;Yakovlev, D. S.;Mal’tsev, D. V.;Kolobrodova, N. A.;Mitina, T. M.;Grechko, O. Yu.. And the article was included in Pharmaceutical Chemistry Journal in 2013.Category: imidazoles-derivatives This article mentions the following:
A series of amides of 2,3-dihydroimidazo- and 2,3,4,10-tetrahydropyrimido[1,2-a]benzimidazolyl-N-acetic acids were synthesized. Their pharmacol. activity was studied. It was established that the synthesized substances possessed antiaggregant properties and antiarrhythmic activity. Some of these amides exhibited antioxidant and hypoglycemic effects in addition to antagonist activity with respect to serotonin 5-HT2 and purine P2Y1 receptors. In the experiment, the researchers used many compounds, for example, 2,3-Dihydro-1H-benzo[d]imidazo[1,2-a]imidazole (cas: 24134-26-7Category: imidazoles-derivatives).
2,3-Dihydro-1H-benzo[d]imidazo[1,2-a]imidazole (cas: 24134-26-7) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Category: imidazoles-derivatives
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem