Synthesis of intermediates of polyamide-DNA recognition molecule was written by Xiao, Junhua;Huang, Chuanqiang;Tang, Feili;Yuan, Gu. And the article was included in Huaxue Tongbao in 2000.Category: imidazoles-derivatives This article mentions the following:
A series of intermediates of polyamide as DNA recognition mols., e.g., dimers, trimers, and tetramers composed of N-methylpyrrole, N-methylimidazole, γ-aminobutyric acid, and β-aminopropionic acid, was prepared by chloroform reaction and DCC (1,3-dicyclohexylcarbodiimide)/HOBT (1-hydroxy-benzotriazole) coupling reaction. In the experiment, the researchers used many compounds, for example, Ethyl 1-methyl-4-nitro-1H-imidazole-2-carboxylate (cas: 109012-23-9Category: imidazoles-derivatives).
Ethyl 1-methyl-4-nitro-1H-imidazole-2-carboxylate (cas: 109012-23-9) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Category: imidazoles-derivatives
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem