Synthesis of 2,3-dichloropropionitrile from chlorination of acrylonitrile catalyzed by ionic liquids was written by Li, Xuehui;Zheng, Binguo;Zhao, Jinggan. And the article was included in Cuihua Xuebao in 2006.Safety of 1-Methyl-3-propylimidazolium Chloride This article mentions the following:
Ionic liquids formed by imidazolium and pyridinium cations with Cl–, Br–, BF–4, and PF–6 anions were used for the catalytic synthesis of 2,3-dichloropropionitrile by the chlorination of acrylonitrile. The ionic liquids containing Cl– and Br– show good catalytic properties. The Cl– and Br– ions act as strong Lewis bases and mol. chlorine is activated by the induction effect of Cl– and Br–. Due to the stronger steric hindrance effect of the BF–4 and PF–6 anions, the chlorination of acrylonitrile is limited in the ionic liquids containing BF–4 and PF–6 anions. In the experiment, the researchers used many compounds, for example, 1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8Safety of 1-Methyl-3-propylimidazolium Chloride).
1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Safety of 1-Methyl-3-propylimidazolium Chloride
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem