Author: Jessica.F

Room-temperature silver-containing liquid metal salts with nitrate anions was written by Schaltin, Stijn;Brooks, Neil R.;Sniekers, Jeroen;Depuydt, Daphne;Van Meervelt, Luc;Binnemans, Koen;Fransaer, Jan. And the article was included in Physical Chemistry Chemical Physics in 2013.Reference of 21252-69-7 This article mentions the following:

The synthesis, structural, thermal and electrochem. properties of F-free Ag-containing ionic liquids are presented. The ionic liquid cations are formed by a Ag(I) ion surrounded by two 1-alkylimidazole ligands, with the counteranions being nitrate ions. Depending on the alkyl chain length, the complexes are liquids at room temperature or melting slightly above this. For the solid compounds it was possible to elucidate the structure by single crystal x-ray anal. The ionic liquids are electroactive, have good mass transport properties and can be used for the electrodeposition of Ag at high current densities. The thermal properties and stability of these compounds were tested by DSC and TGA. The viscosity of the ionic liquids follows a Vogel-Tamman-Fulcher relation as a function of temperature The electrochem. properties of the complexes were tested by cyclic voltammetry and the resulting electrodeposits were examined using SEM and at. force microscopy. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Reference of 21252-69-7).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Reference of 21252-69-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazolium Based Ionic Liquids: Impact of the Cation Symmetry and Alkyl Chain Length on the Enthalpy of Vaporization was written by Yermalayeu, Andrei V.;Zaitsau, Dzmitry H.;Loor, Manuel;Schaumann, Julian;Emel’yanenko, Vladimir N.;Schulz, Stephan;Verevkin, Sergey P.. And the article was included in Zeitschrift fuer Anorganische und Allgemeine Chemie in 2017.Synthetic Route of C11H20N2 This article mentions the following:

The vaporization thermodn. of sym. imidazolium based ionic liquids of the general formula [C_nC_nIm][Br] with the chains length n = 4, 5, 6, and 8 were investigated using a combination of DSC, TGA, and QCM methods with quantum chem. calculations Comparison of vaporization enthalpies for the sym. ([C_nC_nIm][Br]) and asym. imidazolium based ILs ([C_nmim][Br]) revealed a general trend with the lower vaporization enthalpies of the sym. species indicating a significant decrease of the Coulombic interactions affecting energetics of vaporization. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Synthetic Route of C11H20N2).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Synthetic Route of C11H20N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Influence of the Surface Chemistry of Metal-Organic Polyhedra in Their Assembly into Ultrathin Films for Gas Separation was written by Tejedor, Ines;Andres, Miguel A.;Carne-Sanchez, Arnau;Arjona, Monica;Perez-Miana, Marta;Sanchez-Lainez, Javier;Coronas, Joaquin;Fontaine, Philippe;Goldmann, Michel;Roubeau, Olivier;Maspoch, Daniel;Gascon, Ignacio. And the article was included in ACS Applied Materials & Interfaces in 2022.Formula: C11H20N2 This article mentions the following:

The formation of ultrathin films of Rh-based porous metal-organic polyhedra (Rh-MOPs) by the Langmuir-Blodgett method has been explored. Homogeneous and dense monolayer films were formed at the air-water interface either using two different coordinatively alkyl-functionalized Rh-MOPs (HRhMOP(diz)₁₂ and HRhMOP(oiz)₁₂) or by in situ incorporation of aliphatic chains to the axial sites of dirhodium paddlewheels of another Rh-MOP (OHRhMOP) at the air-liquid interface. All these Rh-MOP monolayers were successively deposited onto different substrates in order to obtain multilayer films with controllable thicknesses. Aliphatic chains were partially removed from HRhMOP(diz)₁₂ films post-synthetically by a simple acid treatment, resulting in a relevant modification of the film hydrophobicity. Moreover, the CO₂/N₂ separation performance of Rh-MOP-supported membranes was also evaluated, proving that they can be used as selective layers for efficient CO₂ separation In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Formula: C11H20N2).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Formula: C11H20N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Proton nuclear magnetic resonance spectra of aryl and mono- and disubstituted N-methylazoles was written by Butler, Richard Noel. And the article was included in Canadian Journal of Chemistry in 1973.Recommanded Product: 3034-41-1 This article mentions the following:

Proton NMR spectra of substituted azoles, e.g., methylpyrrole, imidazoles, pyrazoles, etc., are compared. The influence of the azole ring on the chem. shifts of phenyl protons is discussed. A correlation between N-Me chem. shifts and the structural characteristics of the N-Me group in mono- and disubstituted azoles is noted. In the experiment, the researchers used many compounds, for example, 1-Methyl-4-nitroimidazole (cas: 3034-41-1Recommanded Product: 3034-41-1).

1-Methyl-4-nitroimidazole (cas: 3034-41-1) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Recommanded Product: 3034-41-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis of novel cationic copolymer acrylamide/acrylic acid ester by single electron transfer living radical polymerization in aqueous solution was written by Ding, Wei;Liu, Kang;Luan, Huoxin;Yu, Tao;Qu, Guangmiao. And the article was included in Yingyong Huaxue in 2013.HPLC of Formula: 21252-69-7 This article mentions the following:

The imidazole, acrylonitrile, bromooctane were used to synthesize a new cationic polymerizable ionic liquid surfactant named chlorinated-1-octyl-3-(4-butylacrylate-based) imidazole (PMOIH₈). Using 2-chloropropylamide (MPC) as the initiator, Cu⁰ powder and tris-(2-dimethylamino ethyl) amine (Me₆-TREN) as the catalyst, a new kind of copolymer acrylamide/acrylic ester was synthesized via single electron transfer living radical polymerization (SET-LRP) of acrylamide with PMOIH₈. The resulting polymers were analyzed by FT-IR, MS and ¹H NMR, and the results showed that the polymers were target products. The relative mol. mass and the distribution of the resulting polymer were determined by GPC. The relative mol. mass of polymers is within the range of 2 脳 10³鈭?4 脳 10³, and the relative mol. mass distribution is within the range of 1.21鈭?.75. Various factors which might affect the SET-LRP such as catalyst and initiator were discussed. The results showed that as the amount of catalyst reduced, the polymerization rate decreased and the polymerization rate constant (k_p^app) reduced from 0.0168 min^-1 to 0.0065 min^-1, while the relative mol. mass distribution M_w/M_n increased from 1.25鈭?.71 to 1.32鈭?.75, and the initiator efficiency decreased, I_eff = 90.24%. As the amount of initiator increased, the relative mol. mass distribution of the resulting polymer was narrower with M_w/M_n reduced from 1.25鈭?.71 to 1.21鈭?.68, while the polymerization rate constant(k_p^app) increased from 0.0168 min^-1 to 0.0201 min^-1, and the initiator efficiency increased, I_eff = 93.17%. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7HPLC of Formula: 21252-69-7).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. HPLC of Formula: 21252-69-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Pd/[C₂NH₂mim][Br] Thin Film Versus Pd/[C₈mim][Cl] or Pd/[C₈mim][BF₄]: Catalytic Applications in Electrooxidation of Methanol, p-Nitrophenol Reduction and C-C Coupling Reaction was written by Gheitasi Zarooni, Mahtab;Hoseini, S. Jafar;Bahrami, Mehrangiz;Roushani, Mahmoud;Nabavizadeh, S. Masoud. And the article was included in Journal of Inorganic and Organometallic Polymers and Materials in 2020.Quality Control of 1-Methyl-1H-imidazol-3-ium chloride This article mentions the following:

In this study, different ionic liquids including 1-aminoethyl-3-methyl-imidazolium bromide [C₂NH₂mim][Br] (1), 1-methyl-3-octylimidazolium chloride [C₈mim][Cl] (2) and 1-methyl-3-octylimidazolium tetrafluoroborate [C₈mim][BF₄] (3) were applied to stabilize Pd nanoparticles (NPs) at toluene/water interface as thin films. Field emission-SEM (FE-SEM) images showed puckered chains of ionic liquid (1) around the Pd NPs as flower nanostructures. Transmission electron microscopy (TEM) image of Pd/1 showed clearly core-shell nanostructures. Furthermore, applications of Pd/1, Pd/2 and Pd/3 were investigated in the Suzuki-Miyaura C-C coupling reaction in the presence and absence of ultrasonic waves, hydrogenation catalysis of p-nitrophenol reduction and methanol oxidation reaction. Interestingly, J_f (forwarding c.d. due to methanol oxidation) was observed only for Pd/1. We believe that interactions of -NH₂ and imidazolium groups of ionic liquid 1 with Pd particles are very important in producing of puckered shells around the Pd NPs. Injection of electron d. from -NH₂ group and Br^– of ionic liquid 1 to Pd content tends to Pd be softer than other ionic liquids (2 or 3). This effect weakens the strength of Pd-O and facilitates the intermol. reductive elimination between Pd-O and Pd-C鈮僌 in rate-determining step of methanol oxidation to produce CO₂ product. However, electron releasing group accelerates the increasement in neg. charge d. of metal accelerates intramol. or intermol. reduction elimination. Graphic Abstract: Stabilization of Pd nanoparticles from organometallic precursor in the presence of various ionic liquids is investigated. The obtained Pd/ionic liquid thin films were applied in catalytic reactions such as Suzuki-Miyaura C-C coupling reaction, p-nitrophenol reduction and methanol oxidation process for fuel cells. In spite of Pd nanoparticle thin films used for methanol oxidation reaction that exhibit no considerable methanol oxidation, these catalysts exhibit good electrocatalytic activity. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Quality Control of 1-Methyl-1H-imidazol-3-ium chloride).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Quality Control of 1-Methyl-1H-imidazol-3-ium chloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

An efficient process for pretreatment of lignocelluloses in functional ionic liquids was written by Dong, Shi-Jia;Zhang, Bi-Xian;Gao, Yun-Fei;Hu, Xiao-Mei. And the article was included in International Journal of Polymer Science in 2015.Safety of 1-Methyl-1H-imidazol-3-ium chloride This article mentions the following:

The complex structure of the lignocelluloses is the main obstacle in the conversion of lignocellulosic biomass into valuable products. Ionic liquids provide the opportunities for their efficient pretreatment for biomass. Therefore, in this work, pretreatment of corn stalk was carried out in ultrasonic-assisted ionic liquid including 1-butyl-3-methylimidazolium chloride [BMIM]Cl, 1-H-3-methylimidazolium chloride [HMIM]Cl, and 1-(1-propylsulfonic)-3-imidazolium chloride [HSO₃-pMIM]Cl at 70掳C for 2 h.We compared the pretreatments by ionic liquid with and without the addition of deionized water. Fourier transform IR spectroscopy (FTIR) and SEM were employed to analyze the chem. characteristics of regenerated cellulose-rich materials. [HMIM]Cl and [HSO₃-pMIM]Cl were effective in lignin extraction to obtain cellulose-rich materials. FTIR anal. and SEM anal. indicated the effective lignin removal and the reduced crystallinity of cellulose-rich materials. Enzymic hydrolysis of cellulose-rich materials was performed efficiently. High yields of reducing sugar and glucose were obtained when the corn stalk was pretreated by [HMIM]Cl and [HSO₃-pMIM]Cl. Ionic liquids provided the ideal environment for lignin extraction and enzymic hydrolysis of corn stalk and [HMIM]Cl and [HSO₃-pMIM]Cl proved the most efficient ionic liquids This simple and environmentally acceptable method has a great potential for the preparation of bioethanol for industrial production In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Safety of 1-Methyl-1H-imidazol-3-ium chloride).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Safety of 1-Methyl-1H-imidazol-3-ium chloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Strengthened adsorption and corrosion inhibition of new single imidazole-type ionic liquid molecules to copper surface in sulfuric acid solution by molecular aggregation was written by Shi, Yueting;Fu, Yan;Xu, Shenying;Huang, Haijun;Zhang, Shengtao;Wang, Zhenqiang;Li, Wenpo;Li, Hongru;Gao, Fang. And the article was included in Journal of Molecular Liquids in 2021.Recommanded Product: 21252-69-7 This article mentions the following:

This study proposes to use mol. aggregation method of organic ionic liquid mols. (OILMs) to intensify adsorption and corrosion inhibition to copper surface in sulfuric acid solution Three new single imidazole-type OILMs including long carbon chain were synthesized, which were characterized by different methods such as NMR (NMR) and elemental anal. The results suggest that the OILMs could process regular mol. assembly in sulfuric acid solution The formed OILMs aggregates have been shown dependence on the OILMs concentrations and aggregation time. The chem. adsorption of the OILMs aggregates on copper surface was demonstrated by various means including attenuated total reflection IR spectroscopy (ATR-IR), XPS, X-ray diffraction (XRD), and spectroscopic ellipsometry and contacting angles, and at. force microscopy (AFM) as well as SEM (SEM) imaging. Thus, the hydrophobic adsorption layers of the OILMs aggregates were yielded on copper surface. The electrochem. survey suggests that the OILMs aggregates present nice corrosion resistance effect to copper in sulfuric acid solution (the maximal corrosion inhibition efficiency, >93%). The results were further understood by the theor. simulation computation. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Recommanded Product: 21252-69-7).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Recommanded Product: 21252-69-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Diastereoselective Trapping of Transient Carboxylic Oxonium Ylides with 伪,尾-Unsaturated 2-Acyl Imidazoles was written by Zhang, Mengchu;Zhang, Tianyuan;Zhang, Dan;Hu, Wenhao. And the article was included in Advanced Synthesis & Catalysis in 2020.Safety of 1-(1-Methyl-1H-imidazol-2-yl)ethanone This article mentions the following:

A diastereoselective reaction of cyclopropene carboxylic acids with 伪,尾-unsaturated 2-acyl imidazoles was developed to report a Michael-type trapping of transient carboxylic oxonium ylides. This transformation provided a direct approach for the construction of valuable 纬-butenolide derivatives I [R¹ = Ph, 4-FC₆H₄, 3,4,5-trimethoxyphenyl, etc.; R² = Ph, 2-furyl, 4-NCC₆H₄, etc.] in good yields (60-99%) with high diastereoselectivities (up to >95:5 dr) under mild reaction conditions. In the experiment, the researchers used many compounds, for example, 1-(1-Methyl-1H-imidazol-2-yl)ethanone (cas: 85692-37-1Safety of 1-(1-Methyl-1H-imidazol-2-yl)ethanone).

1-(1-Methyl-1H-imidazol-2-yl)ethanone (cas: 85692-37-1) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3鈥揅6) is higher than in water and generally decreases with a Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Safety of 1-(1-Methyl-1H-imidazol-2-yl)ethanone

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Serelaxin and the AT₂ Receptor Agonist CGP42112 Evoked a Similar, Nonadditive, Cardiac Antifibrotic Effect in High Salt-Fed Mice That Were Refractory to Candesartan Cilexetil was written by Wang, Yan;Han, Lei;Shen, Matthew;Jones, Emma S.;Spizzo, Iresha;Walton, Sarah L.;Denton, Kate M.;Gaspari, Tracey A.;Samuel, Chrishan S.;Widdop, Robert E.. And the article was included in ACS Pharmacology & Translational Science in 2020.Name: 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate This article mentions the following:

Fibrosis is involved in the majority of cardiovascular diseases and is a key contributor to end-organ dysfunction. In the current study, the antifibrotic effects of recombinant human relaxin-2 (serelaxin; RLX) and/or the AT₂R agonist CGP42112 (CGP) were compared with those of the established AT₁R antagonist, candesartan cilexetil (CAND), in a high salt-induced cardiac fibrosis model. High salt (HS; 5%) for 8 wk did not increase systolic blood pressure in male FVB/N mice, but CAND treatment alone significantly reduced systolic blood pressure from HS-induced levels. HS significantly increased cardiac interstitial fibrosis, which was reduced by either RLX and/or CGP, which were not additive under the current exptl. conditions, while CAND failed to reduce HS-induced cardiac fibrosis. The antifibrotic effects induced by RLX and/or CGP were associated with reduced myofibroblast differentiation. Addnl., all treatments inhibited the HS-induced elevation in tissue inhibitor of matrix metalloproteinases-1, together with trends for increased MMP-13 expression, that collectively would favor collagen degradation Furthermore, these antifibrotic effects were associated with reduced cardiac inflammation. Collectively, these results highlight that either RXFP1 or AT₂R stimulation represents novel therapeutic strategies to target fibrotic conditions, particularly in HS states that may be refractory to AT₁R blockade. In the experiment, the researchers used many compounds, for example, 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate (cas: 145040-37-5Name: 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate).

1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate (cas: 145040-37-5) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Name: 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem