Author: Jessica.F

Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Recommanded Product: 1H-Imidazole-2-carbaldehyde.

Yadav, Manoj Kumar;Pokhrel, Shanta;Yadav, Paras Nath research published 《 Novel chitosan derivatives of 2-imidazolecarboxaldehyde and 2-thiophenecarboxaldehyde and their antibacterial activity》, the research content is summarized as follows. Chitosan was synthesized from chitin; extracted from prawn shells’ powder via deacetylation and physicochem. properties were studied. Novel chitosan derivatives of 2-imidazolecarboxaldehyde and 2-thiophenecarboxaldehyde were synthesized by refluxing equimolar quantities of resp. aldehyde with chitosan. These functionalized chitosan derivatives were characterized by Fourier transform IR (FTIR), ¹³C-NMR (¹³C-NMR) spectroscopy, elemental anal., X-ray diffraction (XRD), thermogravimetric anal. (TGA) and DTA (DTA) and their antibacterial activity was explored. Chitosan derivative of 2-thiophenecarboxaldehyde was found active against Escherichia coli.

Recommanded Product: 1H-Imidazole-2-carbaldehyde, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole is a five-membered heterocyclic moiety that possesses three carbon, two nitrogen, four hydrogen atoms, and two double bonds. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It is also known as 1, 3-diazole. It contains two nitrogen atoms, in which one nitrogen bear a hydrogen atom, and the other is called pyrrole type nitrogen. Category: imidazoles-derivatives.

Xue, Lei;Zhang, Aiai;Wu, Jinfang;Wang, Qi;Liu, Yang;Zhao, Yuansong;Liu, Shangpeng;Liu, Ze;Li, Ping;Zeng, Shanghong research published 《 Surface modification and reconstruction of ZnO hollow microspheres for selective electroreduction of CO₂ to CO》, the research content is summarized as follows. Surface chem. can be modified by introducing another component on the surface of catalyst due to the regulation of configuration and electronic properties. Herein, the nanostructured ZnO hollow microspheres were fabricated for selective CO₂ reduction to CO. The addition of CuO weakens the strength of adjacent Zn-O bond and improves the formation of more zero-valence Zn. Small CuO entities can provide the active sites for CO₂ adsorption, and the presence of surface defects due to Zn²⁺ reduction could enhance initial dissociation from CO₂ to CO. More interestingly, the 3CuO/ZnO catalyst underwent reconstruction during electrocatalysis, and multi-shelled hollow spheres evolved into a thin flaky structure. The extended surface area of flaky morphol. enhances the catalytic stability despite the occurrence of ZnO reduction This study highlights the importance of surface modification for CO₂ selective reduction to CO but also provides some insights on reconstruction during electrochem. reduction of CO₂.

Category: imidazoles-derivatives, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole based anticancer drug find applications in cancer chemotherapy. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC). Electric Literature of 10111-08-7.

Xu, Yu;Zhang, Xiu-Juan;Li, Wen-Bo;Wang, Xing-Rong;Wang, Shuai;Qiao, Xue-Peng;Chen, Shi-Wu research published 《 Design, synthesis and biological evaluation of indole-2-one derivatives as potent BRD4 inhibitors》, the research content is summarized as follows. A series of indole-2-one derivatives I (R¹ = cyclopropyl, cyclopentyl, 4,5-dihydro-1H-imidazol-2-yl, etc.; R² = H, Me, cyclopropyl, furan-2-yl; R³ = 4-methoxyphenyl, 2,5-difluorophenyl, naphthalen-1-yl, etc.; R¹R² = -(CH₂)₃-, -(CH₂)₅-) and II (R⁴ = 2-methoxyphenyl, cyclohexyl) through scaffold hopping drug design has been designed and synthesized. Most of the compounds showed potent BRD4 inhibitory activities and anti-proliferation activities in cancer cell lines. Especially, compound I (R¹ R² = -(CH₂)₃-; R³ = 2-methoxyphenyl) (II) exhibited excellent BRD4 inhibitory activities (BD1 IC₅₀ = 19 nM, BD2 IC₅₀ = 28 nM) and anti-proliferation potency with IC₅₀ values of 4.75μM and 1.35μM in HT-29 and HL-60 cells, resp. Addnl., docking studies showed that the hydrophobic pocket next to KAc region and WPF shelf were critical to the activity of the compound Compound II could arrest the cell-cycle progression of HT-29 cells into the G1 phase and reduce the expression of c-Myc. Moreover, compound II exhibited favorable oral pharmacokinetic properties. All the results demonstrated that compound II was a potent BRD4 inhibitor and had merely potential for colon cancer treatment.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Electric Literature of 10111-08-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. 3034-50-2, formula is C4H4N2O, Name is Imidazole-4-carbaldehyde. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents. COA of Formula: C4H4N2O.

Xu, Wei;Yao, Hao;Zhang, Xing;Peng, Changjiang;Li, Ling;Zhang, Yuanyuan;Qian, Shan;Yang, Lingling;Wang, Zhouyu research published 《 K₂CO₃ Promoted Cascade Reaction for the Preparation of 1H-Imidazol-4- yl-1-amine Derivatives》, the research content is summarized as follows. A K₂CO₃ promoted efficient one pot two-step method for the preparation of 1H-imidazol-4- yl-1-amine derivatives I [R¹ = Et, Ph, 4-MeC₆H₄, etc.; R² = Ph, 2-ClC₆H₄, Bn, etc.] was developed. A series of secondary amines with an imidazole group were obtained with 56%-91% yields by the K₂CO₃ promoted amination of acetates and nitrogen deprotection of the imidazole process.

3034-50-2, 1H-Imidazole-4-carbaldehyde, also known as 1H-Imidazole-4-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
The starting material for a practical synthesis of a potent C17,20-lyase inhibitor. The lyase is a key enzyme in androgen biosynthesis as well as a target for treatment of androgen-dependent prostate cancer. Used to synthesize potent antimalarial drug.
1H-Imidazole-4-carbaldehyde is a chemical compound that has been shown to bind to the glucocorticoid receptor. It was synthesized by reacting 1,2-diaminobenzene with formaldehyde and then hydrolyzing the intermediate imidazolium salt, which is stable in acidic solutions. The complex can be prepared by mixing two solutions of imidazole and trifluoroacetic acid. The ligand has a redox potential of -0.1 V (vs NHE). This means it can be oxidized to the carbonyl group or reduced back to the imidazole ring. The compound is stable in neutral solution and forms stable complexes with metal ions such as Cu+, Fe3+, and Zn2+. It also coordinates well with oxygen atoms, nitrogen atoms, and water molecules. 1H-Imidazole-4-carbaldehyde has been shown to bind to glucocortic, COA of Formula: C4H4N2O

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. Their solubility in alcohol is lower than that in water and decreases with increasing molecular weight of the alcohols . Quality Control of 10111-08-7.

Xu, Li-Yan;Chai, Yong-Mei;Li, Cheng-Guo;Chai, Lan-Qin research published 《 Co(II) and Cd(II) complexes with imidazole-2-carboxaldehyde groups: spectroscopic, antibacterial, Hirshfeld surfaces analyses, and TD/DFT calculations》, the research content is summarized as follows. Two complexes [Co(L)₂·2CH₃OH]₂·(NO₃)₄ (1) and [Cd(L)₂(NO₃)₂] (2) (L = 2-(2-imidazolyl)-4-methyl-1,2-dihydroquinazoline-3-oxide) were synthesized by natural evaporation of Co (II)/Cd (II) nitrate with a new heterocyclic ligand. The metal complexes are characterized by elemental anal., spectroscopy, and X-ray crystallog. In the crystal structures, Co(II) complex 1 was in a six-coordinated coordination environment and constituted an infinite 1-D chain, 2-D network, Meter-shaped 3-D supramol. framework, while Cd(II) complex 2 assembled into an infinite 1-D, wave-like 2-D, and dragonfly-shaped 3-D skeleton. Specifically, nitrate ions were present as a dissociated group in complex 1, whereas complex 2 was involved in the coordination. Moreover, Cd(II) complex exhibited different fluorescence behaviors in diverse solvents. Remarkably, all the compounds showed perceptible antibacterial activity against Gram-pos. and Gram-neg. bacteria. Furthermore, the electrostatic potential (ESP) calculations were utilized to analyze electrophilic and nucleophilic attack sites on the mol., which verified the existence of hydrogen bonds in the optimized crystal structure. In addition, the structural features of metal complexes have been remarkably rationalized, and the overall trends obtained in the exptl. values have been resoundingly remake by TD/DFT calculations The detailed Hirshfeld surface anal. and fingerprint plots yielded a comparative picture of the mode of non-covalent interactions.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Quality Control of 10111-08-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 3034-50-2, formula is C4H4N2O, Name is Imidazole-4-carbaldehyde. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Formula: C4H4N2O.

Xu, Chang-Jiang;Du, Wei;Albrecht, Lukasz;Chen, Ying-Chun research published 《 Lewis Basic Amine Catalyzed Aza-Michael Reaction of Indole- and Pyrrole-3-carbaldehydes》, the research content is summarized as follows. 3-Formyl substituted indoles or pyrroles can form HOMO-raised dearomative aza-dienamine-type intermediates with secondary amines, which can undergo direct aza-Michael addition to β-trifluoromethyl enones to afford N-alkylated products efficiently, albeit with low to fair enantioselectivity. In addition, similar asym. aza-Michael additions of these heteroarenes and crotonaldehyde are realized under dual catalysis of chiral amines, and the adducts are obtained with moderate to good enantioselectivity.

3034-50-2, 1H-Imidazole-4-carbaldehyde, also known as 1H-Imidazole-4-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
The starting material for a practical synthesis of a potent C17,20-lyase inhibitor. The lyase is a key enzyme in androgen biosynthesis as well as a target for treatment of androgen-dependent prostate cancer. Used to synthesize potent antimalarial drug.
1H-Imidazole-4-carbaldehyde is a chemical compound that has been shown to bind to the glucocorticoid receptor. It was synthesized by reacting 1,2-diaminobenzene with formaldehyde and then hydrolyzing the intermediate imidazolium salt, which is stable in acidic solutions. The complex can be prepared by mixing two solutions of imidazole and trifluoroacetic acid. The ligand has a redox potential of -0.1 V (vs NHE). This means it can be oxidized to the carbonyl group or reduced back to the imidazole ring. The compound is stable in neutral solution and forms stable complexes with metal ions such as Cu+, Fe3+, and Zn2+. It also coordinates well with oxygen atoms, nitrogen atoms, and water molecules. 1H-Imidazole-4-carbaldehyde has been shown to bind to glucocortic, Formula: C4H4N2O

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole is a five-membered heterocyclic moiety that possesses three carbon, two nitrogen, four hydrogen atoms, and two double bonds. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It is also known as 1, 3-diazole. It contains two nitrogen atoms, in which one nitrogen bear a hydrogen atom, and the other is called pyrrole type nitrogen. Reference of 10111-08-7.

Xiong, Wu-Lin;Peng, Xiao-Chong;Zhong, Ren-Yuan;Zheng, Jianwei;Duo, Shuwang;Gong, Shan-Shan;Sun, Hong-bin;Sun, Qi research published 《 Construction of a Clock Catalytic System: Highly Efficient and Self-Indicating Synthesis of Benzoheterocycles at Ambient Temperature》, the research content is summarized as follows. Inspired by the mechanism of the clock reaction, a novel phosphomolybdenum blue (PMB) clock catalytic system was constructed for a highly efficient synthesis of benzimidazoles and benzothiazoles simply at ambient temperature The PMB clock catalytic system exhibited a sharp decoloration event to announce the depletion of the intermediate constraint, making this synthetic approach self-indicating and TLC-free. XPS and ³¹P NMR anal. of PMB catalyst showed that only two Mo⁶⁺ atoms were reduced to Mo⁵⁺ atoms in the Keggin structure due to the moderate reducibility of benzimidazoline and benzothiazoline intermediates. Thus,the active Keggin-type POM cluster could be well maintained in DMSO during the redox cycling of phosphomolybdic acid (PMA) and PMB. The ¹H NMR tracing experiment not only confirmed the proposed reaction mechanism but also showed that PMB exerts Lewis acid catalytic activity at the early phase of the reaction other than the expected redox catalytic activity.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Reference of 10111-08-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole based anticancer drug find applications in cancer chemotherapy. 3034-50-2, formula is C4H4N2O, Name is Imidazole-4-carbaldehyde. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC). Synthetic Route of 3034-50-2.

Xing, Yingying;Dong, Fengying;Yin, Xiangcong;Wang, Liang;Li, Shuai-Shuai research published 《 Facile Construction of 3,4-dihydro-2H-1,2,4-Benzothiadiazine 1,1-Dioxides via Redox-Neutral Cascade Condensation/[1,7]-Hydride Transfer/Cyclization》, the research content is summarized as follows. The benzothiadiazine 1,1-dioxides were highly efficiently constructed via a BF₃.Et₂O promoted redox-neutral cascade condensation/[1,7]-hydride transfer/cyclization, which featured novel substrate skeletons, broad substrate scope, [1,7]-hydride transfer manner, metal-free conditions and the facile introduction of aryl, heteroaryl, allyl and propargyl groups etc.

Synthetic Route of 3034-50-2, 1H-Imidazole-4-carbaldehyde, also known as 1H-Imidazole-4-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
The starting material for a practical synthesis of a potent C17,20-lyase inhibitor. The lyase is a key enzyme in androgen biosynthesis as well as a target for treatment of androgen-dependent prostate cancer. Used to synthesize potent antimalarial drug.
1H-Imidazole-4-carbaldehyde is a chemical compound that has been shown to bind to the glucocorticoid receptor. It was synthesized by reacting 1,2-diaminobenzene with formaldehyde and then hydrolyzing the intermediate imidazolium salt, which is stable in acidic solutions. The complex can be prepared by mixing two solutions of imidazole and trifluoroacetic acid. The ligand has a redox potential of -0.1 V (vs NHE). This means it can be oxidized to the carbonyl group or reduced back to the imidazole ring. The compound is stable in neutral solution and forms stable complexes with metal ions such as Cu+, Fe3+, and Zn2+. It also coordinates well with oxygen atoms, nitrogen atoms, and water molecules. 1H-Imidazole-4-carbaldehyde has been shown to bind to glucocortic, 3034-50-2.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 1739-84-0, formula is C5H8N2, Name is 1,2-Dimethyl-1H-imidazole. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Product Details of C5H8N2.

Xing, Yi;Geng, Kang;Chu, Xiaomeng;Wang, Chenyi;Liu, Lei;Li, Nanwen research published 《 Chemically stable anion exchange membranes based on C2-Protected imidazolium cations for vanadium flow battery》, the research content is summarized as follows. Imidazolium-based anion exchange membranes (AEMs) are attractive as the separator for vanadium redox flow battery (VFB) application. However, the lack of fundamental understanding of the correlations between imidazolium chem. structure and their phys. properties as well as cell performance constraints the design of advanced AEMs in VFBs. In this work, by designing the “clickable” imidazolium compounds from C2-Me or C2-Ph substituted imidazolium to C2-Ph substituted benzimidazolium, a series of PSf-based AEMs having pendant C2-protected imidazolium derivatives were prepared by efficient CuAAC reaction to explore how the nature of C2 substitution affected the electrochem. property of AEMs and the resulting VFB performance. Interestingly, PSf-MIm with C2-Me protected imidazolium group showed lowest area resistance (0.3 Ω cm², IEC = 1.66 meq./g) in 3 M H₂SO₄ aqueous solution but unfavorable vanadium permeability due to its highest swelling ratio. The introduction of bulky C2-Ph substituted benzimidazolium led to the distinct microphase separation in PSf-PhBIm membrane, and thus reduced water uptake, high vanadium selectivity, and comparable conductivity were observed As a result, the single VFB with PSf-MIm-1.2 membrane exhibited better electrochem. performance with a coulombic efficiency (CE) of 97.0%, and an energy efficiency (EE) of 82.4% at a c.d. of 120 mA/cm², higher than those of Nafion N115 membrane (EE = 75.5%) and unsubstituted imidazolium-based AEMs (EE = 80.6%). More importantly, both ex situ stability testing in 1.5 M (VO₂)₂SO₄/3 M H₂SO₄ solution for 90 days and in situ cycling performance at a c.d. of 120 mA/cm² demonstrated that the chem. structure of C2-substituted imidazolium based AEMs remained intact after stability tests as confirmed by NMR anal., while significant degradation was found for unsubstituted PSf-Im membrane via possible nucleophilic addition mechanism. Therefore, the VFB with PSf-MIm membrane showed the best long-term durability with only 34.1% loss in EE for 3638 h of operating (4800 cycles). This work not only fills the knowledge gap on the structure-property relationship of imidazolium-based AEMs for VFB application, but also gives us new directions to design stable AEMs for durable VFBs.

Product Details of C5H8N2, 1,2-Dimethylimidazole is used in the synthesis of 1,2-dimethyl-3-n-butylimidazoliumchloride and 1,2-dimethyl-3-n-propylimidazolium chloride. It also can be used in the synthesis of 1-(2-methoxyethyl)-2,3-dimethylimidazolium chloride and hexafluorophosphate salts.
1,2-Dimethylimidazole is a heterocyclic compound that contains nitrogen and carbon. It can be produced by the reaction between glyoxal and fatty acid in the presence of a base. 1,2-Dimethylimidazole has been shown to have biological properties such as an antioxidant effect. It is also used as a chemical intermediate for production of other chemicals such as 2-methylimidazole and 3-methylimidazole. 1,2-Dimethylimidazole has been shown to react with metal carbonyls to produce methylimines, which are useful intermediates in organic synthesis. The reaction mechanism involves hydrogen bonding and steric interactions between the imidazole ring and the metal carbonyl reactant., 1739-84-0.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents. Reference of 10111-08-7.

Xie, Ting;Wang, Guo-Qiang;Wang, Ya-Wen;Rao, Weidong;Xu, Haiyan;Li, Shuhua;Shen, Zhi-Liang;Chu, Xue-Qiang research published 《 Selective Quadruple C(sp³)-F Functionalization of Polyfluoroalkyl Ketones》, the research content is summarized as follows. An unprecedented coupling-aromatization-cyclization reaction of polyfluorinated ketones with diverse N- and S-nucleophiles that formed regio-defined perfluoroalkylated naphtho[1,2-b]furan/benzofuran derivatives by harnessing Co-promoted distinctive quadruple C(sp³)-F bonds cleavage relay. This chem. involving controlled and successive selective defluorination at heteronuclear centers greatly contributed to the preparation of drug-like heterocycles as well as the late-stage elaboration of biorelevant compounds Controlled experiments and DFT theor. studies revealed that the combination of cheap cobalt salt with Cs₂CO₃ enabled expeditious C-F functionalization.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Reference of 10111-08-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem