Author: Jessica.F

Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 1739-84-0, formula is C5H8N2, Name is 1,2-Dimethyl-1H-imidazole. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Product Details of C5H8N2.

Wang, Jian;Li, Yuao;Chen, Xiguang;Wei, Ning;Tong, Jing research published 《 Excess properties and activation properties for viscous flow of amino acid ionic liquids with H₂O binary mixtures》, the research content is summarized as follows. Amino acid ionic liquids (ILs) 1-butyl-2,3-dimethylimidazolium glycine ([C₄Dmim][Gly]), 1-butyl-2,3-dimethylimidazolium alanine ([C₄Dmim][Ala]) and 1-butyl-2,3-dimethylimidazolium threonine ([C₄Dmim][Thr]) were prepared Over the temperature from (288.15-318.15) K, the d., surface tension and viscosity for binary system mixtures of ILs with H₂O were measured, and excess thermodn. properties and activation properties for viscous flow of these binary system mixtures were systematically studied. Secondly, the variation trend between excess molar volume (VE)/excess molar surface Gibbs energy (gEs) and mole fraction for ILs + H₂O binary system mixtures was investigated. With the increase of mole fraction, the VE and gEs values of binary system mixtures increased firstly and then decreased, and they were pos. value, which may be due to the weak chem. interaction between ILs and H₂O in the mixture Furthermore, according to the thermodn. formula, the Gibbs energy of activation for viscous flow of the relative viscosity (ΔG^≠_r), activation entropy (ΔS^≠_r) and activation enthalpy (ΔH^≠_r) were calculated Over the entire concentration range, the ΔG^≠_r values for binary system mixtures of ILs with H2O were neg. value, and the result was in good agreement with relative viscosity (η_r).

Product Details of C5H8N2, 1,2-Dimethylimidazole is used in the synthesis of 1,2-dimethyl-3-n-butylimidazoliumchloride and 1,2-dimethyl-3-n-propylimidazolium chloride. It also can be used in the synthesis of 1-(2-methoxyethyl)-2,3-dimethylimidazolium chloride and hexafluorophosphate salts.
1,2-Dimethylimidazole is a heterocyclic compound that contains nitrogen and carbon. It can be produced by the reaction between glyoxal and fatty acid in the presence of a base. 1,2-Dimethylimidazole has been shown to have biological properties such as an antioxidant effect. It is also used as a chemical intermediate for production of other chemicals such as 2-methylimidazole and 3-methylimidazole. 1,2-Dimethylimidazole has been shown to react with metal carbonyls to produce methylimines, which are useful intermediates in organic synthesis. The reaction mechanism involves hydrogen bonding and steric interactions between the imidazole ring and the metal carbonyl reactant., 1739-84-0.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . 1739-84-0, formula is C5H8N2, Name is 1,2-Dimethyl-1H-imidazole. In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with an increase of the alkyl chain length of the alcohols. SDS of cas: 1739-84-0.

Wang, Jian;Wu, Junshuang;Wu, Wenqing;Tong, Jing research published 《 Estimation of the polarity and prediction of the molar surface Gibbs energy for amino acid ionic liquids – [C₄Dmim][Gly] and [C₄Dmim][Ala]》, the research content is summarized as follows. 1-Butyl-2,3-dimethylimidazolium glycine ([C₄Dmim][Gly]) and 1-butyl-2,3-dimethylimidazolium alanine ([C₄Dmim][Ala]) were synthesized by neutralization method and characterized by ¹H NMR and ¹³C NMR spectrum. The exptl. values of the d., surface tension and refractive index of two amino acid ionic liquids were measured by standard addition method. Firstly, the polarity coefficients of [C₄Dmim][Gly] and [C₄Dmim][Ala] were calculated by polarity coefficient (P), and the polarity trend of other ionic liquids (ILs) was predicted. For the same anion, the polarity values of the same series of ILs decrease with increasing carbon chain length, and the anion species also affect the polarity of ILs. Secondly, according to the relationship between the slope of the new Eotvos empirical equation and the molar surface entropy (s), the polarity values of other ILs were also estimated and the conclusion obtained was basically consistent with polarity coefficient Furthermore, the predicted molar surface Gibbs energy values of samples were obtained by the new Eotvos empirical equation, and the predicted values were highly consistent with the corresponding exptl. values.

1739-84-0, 1,2-Dimethylimidazole is used in the synthesis of 1,2-dimethyl-3-n-butylimidazoliumchloride and 1,2-dimethyl-3-n-propylimidazolium chloride. It also can be used in the synthesis of 1-(2-methoxyethyl)-2,3-dimethylimidazolium chloride and hexafluorophosphate salts.
1,2-Dimethylimidazole is a heterocyclic compound that contains nitrogen and carbon. It can be produced by the reaction between glyoxal and fatty acid in the presence of a base. 1,2-Dimethylimidazole has been shown to have biological properties such as an antioxidant effect. It is also used as a chemical intermediate for production of other chemicals such as 2-methylimidazole and 3-methylimidazole. 1,2-Dimethylimidazole has been shown to react with metal carbonyls to produce methylimines, which are useful intermediates in organic synthesis. The reaction mechanism involves hydrogen bonding and steric interactions between the imidazole ring and the metal carbonyl reactant., SDS of cas: 1739-84-0

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole based anticancer drug find applications in cancer chemotherapy. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC). Category: imidazoles-derivatives.

Wang, Jian Hua;Liu, Yao Ming;Chao, Jian Bin;Wang, Hui;Wang, Yu;Shuang, ShaoMin research published 《 A simple but efficient fluorescent sensor for ratiometric sensing of Cd²⁺ and bio-imaging studies》, the research content is summarized as follows. A very simple schiff base fluorescent probe (NIS) was facilely prepared via a one-step, one-pot condensation reaction between 2, 3-naphthalenediamine and imidazole-2-carboxaldehyde. Among common biol. relevant metal ions, NIS can selectively recognize Cd²⁺ via ratiometric fluorescence signal. The chelation of NIS with the Cd²⁺ ions resulted in a fluorescence enhancement together with a blue shift (∼74 nm) in the emission maxima, presumably due to the combined effects of ICT (internal charge transfer) and CHEF (chelation-enhanced fluorescence). The binding stoichiometry of NIS to Cd²⁺ is 1:1 and the fluorescence intensity ratio (F₃₉₈/F₄₇₂) changes allow a ratiometric detection of Cd²⁺ with the detection limit of 3.87 × 10^-7 M. Under fluorescence confocal microscope and via two emission channels, the probe is capable to detect Cd²⁺ ions in Human liver cancer cells (SMMC-7721), zebrafish and live tissues of Arabidopsis thaliana, demonstrating its applicability for detecting Cd²⁺ ions in different biol. context with low toxicity.

Category: imidazoles-derivatives, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. Their solubility in alcohol is lower than that in water and decreases with increasing molecular weight of the alcohols . Recommanded Product: 1H-Imidazole-2-carbaldehyde.

Wang, Jian Hua;Liu, Yao Ming;Chao, Jian Bin;Wang, Yu;Wang, Hui;Shuang, Shao Min research published 《 A phenazine-imidazole based ratiometric fluorescent probe for Cd²⁺ ions and its application in in vivo imaging》, the research content is summarized as follows. A new phenazine-imidazole based Schiff base (PIS) fluorescent probe has been developed for the ratiometric detection of Cd²⁺ ions in aqueous media at physiol. pH. PIS upon binding with Cd²⁺ ions shows red shifted fluorescence and thereby, permits ratiometric detection of Cd(II) ions. A detection limit down to 2.10 x 10^-8 M was determined for Cd²⁺ quantitation. Also, the accompanying apparent fluorescence color change (from yellow to orange red) is noticeable to the naked eye under a UV-lamp. The sensing mechanism could be attributed to the 1 : 1 PIS-Cd complexation, followed by extension of the conjugation due to better planarity and modulation of the charge transfer efficiency in the probe. This was complemented by solvatochromism and d. functional theory calculations Furthermore, PIS was used to detect Cd²⁺ in Oxya chinensis cells, zebrafish larvae and live tissues of Arabidopsis thaliana under a fluorescence microscope, showing great potential in analyzing living biosystems.

Recommanded Product: 1H-Imidazole-2-carbaldehyde, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Formula: C4H4N2O.

Wang, Huanhuan;Bao, Yuheng;Qiu, Huiqiang;Tong, Weijun research published 《 Encapsulation of Methylene Blue in Zeolitic Imidazolate Framework-90 Nanoparticles to Protect Its Photodynamic Activity》, the research content is summarized as follows. Methylene blue (MB) is widely used as a photosensitizer in photodynamic therapy applications. However, it is easily reduced by reductases in biol. environments, which hampers its further applications. Here, we developed a one-pot method to synthesize MB-encapsulated and poly(vinylpyrrolidone) (PVP)-modified zeolitic imidazolate framework-90 (ZIF-90) nanoparticles (MB@ZIF-90/PVP NPs). The NPs show intact crystalline structure with improved colloidal dispersity and stability both in water and in the medium for cell culture. The size of the enzymes is much larger than the pore size of ZIF-90; thus, the access of reductive enzymes to encapsulated MB is prohibited, resulting in the protection of MB′s photodynamic activity. Furthermore, cell experiments confirm that MB@ZIF-90/PVP NPs have lower dark cytotoxity than equivalent free MB but can efficiently induce photodynamic damage to tumor cells even in the presence of reductive enzymes upon light irradiation

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Formula: C4H4N2O

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole is a five-membered heterocyclic moiety that possesses three carbon, two nitrogen, four hydrogen atoms, and two double bonds. 1739-84-0, formula is C5H8N2, Name is 1,2-Dimethyl-1H-imidazole. It is also known as 1, 3-diazole. It contains two nitrogen atoms, in which one nitrogen bear a hydrogen atom, and the other is called pyrrole type nitrogen. Electric Literature of 1739-84-0.

Wang, Yijie;Li, Aoshuang;Cheng, Chuanwei research published 《 Ultrathin Co(OH)₂ Nanosheets@Nitrogen-Doped Carbon Nanoflake Arrays as Efficient Air Cathodes for Rechargeable Zn-Air Batteries》, the research content is summarized as follows. Developing highly active, cost-effective, and durable bifunctional oxygen electrocatalysts is an important step for the advancement of rechargeable Zn-air batteries (ZABs). Herein, an efficient bifunctional oxygen electrocatalyst of ultrathin Co(OH)₂ nanosheets supported on nitrogen-doped carbon nanoflake arrays (named as Co(OH)₂@NC), is reported, which yields excellent bifunctional activity, i.e., a low overpotential of 285 mV to reach 10 mA cm-2 for oxygen evolution reaction (OER), a high half-wave potential (0.83 V) for oxygen reduction reaction (ORR), and a low potential gap (ΔE) of 0.69 V. The excellent bifunctional catalytic performance can be ascribed to the concerted efforts of cobalt hydroxide toward OER and nitrogen-doped carbon for ORR. The Co(OH)₂@NC nanoflake arrays is further used as binder-free air cathodes for rechargeable Zn-air batteries, exhibiting a high specific capacity of 798.3 mAh gZn-1, improved stability (a working life of >70 h at 5 mA cm-2), as well as a reduced long-term charging voltage, which outperforms the counterparts of NC nanoflake arrays and Pt/C-based air cathodes. One step further, the Co(OH)₂@NC nanoflake arrays on carbon cloth are directly used as binder-free air cathodes for flexible, solid-state ZABs, showing excellent performance under deformation as well.

1739-84-0, 1,2-Dimethylimidazole is used in the synthesis of 1,2-dimethyl-3-n-butylimidazoliumchloride and 1,2-dimethyl-3-n-propylimidazolium chloride. It also can be used in the synthesis of 1-(2-methoxyethyl)-2,3-dimethylimidazolium chloride and hexafluorophosphate salts.
1,2-Dimethylimidazole is a heterocyclic compound that contains nitrogen and carbon. It can be produced by the reaction between glyoxal and fatty acid in the presence of a base. 1,2-Dimethylimidazole has been shown to have biological properties such as an antioxidant effect. It is also used as a chemical intermediate for production of other chemicals such as 2-methylimidazole and 3-methylimidazole. 1,2-Dimethylimidazole has been shown to react with metal carbonyls to produce methylimines, which are useful intermediates in organic synthesis. The reaction mechanism involves hydrogen bonding and steric interactions between the imidazole ring and the metal carbonyl reactant., Electric Literature of 1739-84-0

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole is a five-membered heterocyclic moiety that possesses three carbon, two nitrogen, four hydrogen atoms, and two double bonds. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It is also known as 1, 3-diazole. It contains two nitrogen atoms, in which one nitrogen bear a hydrogen atom, and the other is called pyrrole type nitrogen. Computed Properties of 10111-08-7.

Wang, Yifeng;Luo, Xi;Sun, Xiaolong;Hu, Jiahuan;Guo, Qing;Shen, Baoxing;Fu, Yongqian research published 《 Lactate dehydrogenase encapsulated in a metal-organic framework: A novel stable and reusable biocatalyst for the synthesis of D-phenyllactic acid》, the research content is summarized as follows. In this study, we synthesized a novel biocatalyst by encapsulating lactate dehydrogenase (LDH) in the metal-organic framework ZIF-90 by one-pot embedding. It showed strong biol. activity for efficient synthesis of -phenyllactic acid (-PLA). The morphol. and structure of LDH@ZIF-90 was systematically characterized by powder X-ray diffraction (XRD), SEM (SEM), Fourier transform IR (FT-IR) spectroscopy, confocal laser scanning microscopy (CLSM) and gas sorption. According to thermogravimetric anal. (TGA), the enzyme loading of the biocatalyst was 3%. The Michaelis-Menten constant (Km) and maximal reaction rate (Vmax) of LDH@ZIF-90 were similar to those of free LDH, which proved that ZIF-90 had good biocompatibility to encapsulate LDH. At the same time, LDH@ZIF-90 exhibited enhanced tolerance to temperature, pH and organic solvents, and its reusability was greatly improved with 68% of initial enzyme activity remaining after 7 rounds of recylcing. Overall, LDH encapsulated in ZIF-90 may be an economically competitive and environmentally friendly novel biocatalyst for the synthesis of -PLA.

Computed Properties of 10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. 250285-32-6, formula is C27H37ClN2, Name is 1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents. Synthetic Route of 250285-32-6.

Wang, Yichun;Jia, Deyang;Zeng, Jing;Liu, Yuming;Bu, Xiubin;Yang, Xiaobo research published 《 Benzocarbazole Synthesis via Visible-Light-Accelerated Rh(III)-Catalyzed C-H Annulation of Aromatic Amines with Bicyclic Alkenes》, the research content is summarized as follows. A visible-light-accelerated Rh(III)-catalyzed C-H annulation of aromatic amines with bicyclic alkenes for the synthesis of benzocarbazole derivatives, e.g., I was developed. In this approach, with the cooperation of rhodium catalysis and visible-light irradiation, various aromatic amines reacted with oxabicyclic alkenes and azabicyclic alkenes smoothly at room temperature, delivering the corresponding bridged oxa or aza tetrahydro benzocarbazoles in good to excellent yields. Moreover, a series of benzo[b]carbazoles were synthesized conveniently through further aromatization in one pot. The potential of this method was demonstrated via directing-group removal, derivatization, a scale-up reaction, and fluorescence investigations.

250285-32-6, 1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride, also known as 1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride, is a useful research compound. Its molecular formula is C27H37ClN2 and its molecular weight is 425 g/mol. The purity is usually 95%.

1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride has been used to generate N-heterocyclic carbene catalysts for use in carbonylative cross-coupling of pyridyl halides with aryl boronic acids.

1,3-Bis(2,6-diisopropylphenyl)imidazolium Chloride is an imidazolium salt that is active against all stages of Trypanosoma cruzi and may represent a promising candidate for treatment of Chagas disease.

1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride is an organic compound that is used as a solvent. It was originally synthesized by reacting triethyl orthoformate with 2,6-diisopropylaniline. This reaction formed the corresponding imidazolium salt. The synthesis of this compound was later improved by using ring-opening polymerization of glycolide and furfural. 1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride is mainly used to extract estradiol from urine samples in clinical laboratories., Synthetic Route of 250285-32-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 3034-50-2, formula is C4H4N2O, Name is Imidazole-4-carbaldehyde. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Application In Synthesis of 3034-50-2.

Wang, Yanyan;Xu, Fangzhou;Luo, Dexia;Guo, Shengxin;He, Feng;Dai, Ali;Song, Baoan;Wu, Jian research published 《 Synthesis of Anthranilic Diamide Derivatives Containing Moieties of Trifluoromethylpyridine and Hydrazone as Potential Anti-Viral Agents for Plants》, the research content is summarized as follows. A series of novel anthranilic diamide derivatives I (R = 4-Cl-2-Me, 4,6-di-F, 6-Me, etc.; Ar = thiophen-2-yl, 5-bromopyridin-2-yl, iso-Pr, etc.) containing moieties of trifluoromethylpyridine and hydrazone was synthesized and evaluated in vivo for their activities against tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV). Few compounds had the curative activity over 65% against TMV at the concentration of 500 μg/mL, which were significantly higher than those of ningnanmycin (55.0%) and ribavirin (37.9%). Notably, the curative activity of compound I (R = 4-Cl-2-Me, Ar = 5-Me-thien-2-yl) was up to 79.5%, with the EC₅₀ value of 75.9 μg/mL, whereas the EC₅₀ value of ningnanmycin was 362.4 μg/mL and pot experiments also further demonstrated the significantly curative effect of the compound Meanwhile, few compounds displayed more protective activities on TMV than that of ningnanmycin. Moreover few, compounds showed inactivation activity similar to ningnanmycin at 500 μg/mL, and the EC₅₀ value of I (R = 4-Cl-2-Me, Ar = 2-CH₃C₆H₄) (41.5 μg/mL) was lower than ningnanmycin (50.0 μg/mL). The findings of TEM indicated that the synthesized compounds exhibited strong and significant binding affinity to TMV coat protein (CP) and could obstruct the self-assembly and increment of TMV particles. Microscale thermophoresis (MST) studies on TMV-CP and CMV CP revealed that some of the active compounds, particularly I (R = 4-Cl-2-Me, Ar = 5-Me-thien-2-yl) exhibited a strong binding capability to TMV-CP or CMV-CP.

Application In Synthesis of 3034-50-2, 1H-Imidazole-4-carbaldehyde, also known as 1H-Imidazole-4-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
The starting material for a practical synthesis of a potent C17,20-lyase inhibitor. The lyase is a key enzyme in androgen biosynthesis as well as a target for treatment of androgen-dependent prostate cancer. Used to synthesize potent antimalarial drug.
1H-Imidazole-4-carbaldehyde is a chemical compound that has been shown to bind to the glucocorticoid receptor. It was synthesized by reacting 1,2-diaminobenzene with formaldehyde and then hydrolyzing the intermediate imidazolium salt, which is stable in acidic solutions. The complex can be prepared by mixing two solutions of imidazole and trifluoroacetic acid. The ligand has a redox potential of -0.1 V (vs NHE). This means it can be oxidized to the carbonyl group or reduced back to the imidazole ring. The compound is stable in neutral solution and forms stable complexes with metal ions such as Cu+, Fe3+, and Zn2+. It also coordinates well with oxygen atoms, nitrogen atoms, and water molecules. 1H-Imidazole-4-carbaldehyde has been shown to bind to glucocortic, 3034-50-2.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. 3034-50-2, formula is C4H4N2O, Name is Imidazole-4-carbaldehyde. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents. Computed Properties of 3034-50-2.

Wang, Xue-Zhi;Sun, Meng-Ying;Huang, Zhijin;Xie, Mo;Huang, Ruishan;Lu, Huihui;Zhao, Zujin;Zhou, Xiao-Ping;Li, Dan research published 《 Turn-On Circularly Polarized Luminescence in Metal-Organic Frameworks》, the research content is summarized as follows. The fabrication of circularly polarized luminescence (CPL) active materials by self-assembly is still in its challenge. In this work, a family of homochiral metal-organic frameworks (MOFs) and metal-organic cages (MOCs) are constructed by solvothermal subcomponent self-assembly. These MOFs feature an eta topol. with trifold helical chains, while the MOCs adopt a cubic cage structure. The chiral ligands show two distinct types of conformations: “opened” and “closed” in MOFs and MOCs, resp. Although homochiral MOFs and MOCs show similar spectra of CD and photoluminescence with similar quantum yields and lifetimes, the MOFs yield clear CPL signals and the CPL of MOCs are silent. The turn-on CPL in MOFs achieved by tuning the conformation of ligands and controlling self-assembly provides a new approach for development of CPL-active MOF materials.

Computed Properties of 3034-50-2, 1H-Imidazole-4-carbaldehyde, also known as 1H-Imidazole-4-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
The starting material for a practical synthesis of a potent C17,20-lyase inhibitor. The lyase is a key enzyme in androgen biosynthesis as well as a target for treatment of androgen-dependent prostate cancer. Used to synthesize potent antimalarial drug.
1H-Imidazole-4-carbaldehyde is a chemical compound that has been shown to bind to the glucocorticoid receptor. It was synthesized by reacting 1,2-diaminobenzene with formaldehyde and then hydrolyzing the intermediate imidazolium salt, which is stable in acidic solutions. The complex can be prepared by mixing two solutions of imidazole and trifluoroacetic acid. The ligand has a redox potential of -0.1 V (vs NHE). This means it can be oxidized to the carbonyl group or reduced back to the imidazole ring. The compound is stable in neutral solution and forms stable complexes with metal ions such as Cu+, Fe3+, and Zn2+. It also coordinates well with oxygen atoms, nitrogen atoms, and water molecules. 1H-Imidazole-4-carbaldehyde has been shown to bind to glucocortic, 3034-50-2.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem