Liu, Sheng team published research in Journal of Radioanalytical and Nuclear Chemistry in 2022 | 10111-08-7

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Electric Literature of 10111-08-7

Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Electric Literature of 10111-08-7.

Liu, Sheng;Zeng, Yiyang;Zhang, Ai;Song, Yuxin;Xu, Jichen;Ni, Yuran;Pu, Ailin;Yang, Long;Chi, Fangting research published 《 High selectivity of oxime-modified ZIFs to uranium》, the research content is summarized as follows. Abstract: Seawater contains a large amount of uranium resources, which can meet the needs of current nuclear energy development. We designed and synthesized the oxime-modified ZIFs material, grafted the oxime group on the imidazole ligand, and improved the selective adsorption ability of uranium. In simulated seawater experiments, its adsorption effect on uranium is much higher than vanadium. The sorption could reach equilibrium with a capacity of 625 mg/g within 0.17 h at pH 5.0. Compared with the often sorbent, the oxime-modified sorbent showed faster kinetics, higher selectivity and higher extraction capacity for uranium extraction This experiment provides an effective method for designing a highly selective sorbent for uranium, and broadens the ideas for the development of new seawater uranium extraction sorbents.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Electric Literature of 10111-08-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Liu, Yan team published research in Journal of Membrane Science in 2022 | 10111-08-7

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Electric Literature of 10111-08-7

Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. Their solubility in alcohol is lower than that in water and decreases with increasing molecular weight of the alcohols . Electric Literature of 10111-08-7.

Liu, Yan;Xie, Wei;Liang, Shuang;Li, Xingxun;Fan, Yanfang;Luo, Shuangjiang research published 《 Polyimide/ZIFs mixed matrix membranes with tunable interfacial interaction for efficient gas separation》, the research content is summarized as follows. Manipulating favorable interfacial microstructure is crucial to rationally design a high-performance mixed matrix membrane with defect-free interface. We describe herein an efficient pathway to finely tune the interfacial adhesion through balancing the metal organic frameworks and polymer functionality. The varied number of hydrogen bonds are established involving the CHO groups in hybrid ZIF-8-90(x) fillers with varied carboxaldehyde-2-imidazole linker contents and 6FDA-DAM:DABA copolyimides having adjustable COOH groups concentrations, thereby precisely controlling the membrane interfacial bonding behavior. As expected, the gas selectivity of the resulting membranes is gradually enhanced with increasing carboxaldehyde-2-imidazole linker substitution ratio in ZIF-8-90(x), mainly contributed by significant improvements in hydrogen bonding strength. The enhanced interaction is confirmed by good adhesion visualized in SEM images and the C=O vibration band shift in FTIR spectra. Meanwhile, adjusting the proportion of DABA moiety in polymers is an auxiliary path to regulate the interfacial bonding strength. The optimized membrane of 6FDA-DAM:DABA (1:1)/10 weight% ZIF-8-90(30) has enhanced H2/CH4 and CO2/CH4 ideal selectivities of 75.4 and 43.6, resp., with H2 and CO2 permeabilities of 222 Barrer and 128 Barrer. These findings imply that progressively regulating filler and polyimide functionality is a feasible route to finely tailor interfacial hydrogen bonding strength to achieve a membrane with tunable separation performance.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Electric Literature of 10111-08-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Li, Jingyao team published research in ACS Combinatorial Science in 2020 | 10111-08-7

Synthetic Route of 10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Imidazole is a five-membered heterocyclic moiety that possesses three carbon, two nitrogen, four hydrogen atoms, and two double bonds. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It is also known as 1, 3-diazole. It contains two nitrogen atoms, in which one nitrogen bear a hydrogen atom, and the other is called pyrrole type nitrogen. Synthetic Route of 10111-08-7.

Li, Jingyao;Di Lorenzo, Vincenzo;Patil, Pravin;Ruiz-Moreno, Angel J.;Kurpiewska, Katarzyna;Kalinowska-Tluscik, Justyna;Velasco-Velazquez, Marco A.;Doemling, Alexander research published 《 Scaffolding-Induced Property Modulation of Chemical Space》, the research content is summarized as follows. Tetrazole- and heterocycle-containing amino alcs. were prepared by Ugi reactions; the amino alcs. underwent cyclization reactions with carbonyl-, thiocarbonyl-, and sulfonyldiimidazole to yield cyclized products, including benzoxazinones and benzoxazepanones, such as I. Two pyrrole- and imidazole-containing amines were also prepared using Ugi reactions; cyclization reactions with carbonyldiimidazole yielded fused imidazolidinones. The properties (lipophilicity, polar surface area, mol. shape) of virtual libraries of uncyclized and cyclized products were compared. The structures of five of the cyclized products were determined by X-ray crystallog.

Synthetic Route of 10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Li, Jun team published research in Analytical Methods in 2021 | 10111-08-7

Formula: C4H4N2O, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. Their solubility in alcohol is lower than that in water and decreases with increasing molecular weight of the alcohols . Formula: C4H4N2O.

Li, Jun;Weng, Yingwei;Shen, Can;Luo, Jiao;Yu, Donghong;Cao, Zhong research published 《 Sensitive fluorescence and visual detection of organophosphorus pesticides with a Ru(bpy)32+-ZIF-90-MnO2 sensing platform》, the research content is summarized as follows. Fluorescence sensing organophosphorus pesticides (OPs) is of great importance for both food safety and global environment; however, the reported fluorescent probes are usually directly exposed to the external environment, resulting in premature leakage or photobleaching and thus limiting their photostability and assay sensitivity. In this work, a fluorescent sensing platform consisting of a novel luminescent metal-organic framework (Ru(bpy)32+-ZIF-90) and manganese dioxide nanosheets (MnO2 NSs) was prepared for sensing OPs. Due to the protection and improvement in the fluorescence of Ru(bpy)32+ by ZIF-90, the Ru(bpy)32+-ZIF-90 probe displayed remarkable photostability and high stability in water. By virtue of the high stability of Ru(bpy)32+-ZIF-90, as well as the outstanding fluorescence quenching and notable recognition ability of the MnO2 NSs, this sensing platform provided excellent detection capability for parathion-Me, with a wide concentration range of 0.050-60 ng mL-1 and a low detection limit of 0.037 ng mL-1. Addnl., the system exhibited a visual color change with the concentration of the OPs under sunlight. Moreover, satisfactory recoveries ranging from 93.3% to 103.6% were obtained for the real samples. The results indicated that the Ru(bpy)32+-ZIF-90-MnO2-based OP sensing platform is promising for applications in food safety and environmental monitoring.

Formula: C4H4N2O, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Li, Mengde team published research in ACS Applied Energy Materials in 2021 | 10111-08-7

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Recommanded Product: 1H-Imidazole-2-carbaldehyde

Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. Their solubility in alcohol is lower than that in water and decreases with increasing molecular weight of the alcohols . Recommanded Product: 1H-Imidazole-2-carbaldehyde.

Li, Mengde;Liu, Junjie;Deng, Shuping;Liu, Qian;Qi, Ning;Chen, Zhiquan research published 《 Low-pressure CO2 capture in zeolite imidazole frameworks with ultramicropores studied by positron annihilation》, the research content is summarized as follows. In this paper, three kinds of zeolite imidazole frameworks (ZIF-90, ZIF-93, and ZIF-94) were synthesized through hydrothermal reactions. Positron lifetime results reveal two kinds of pores corresponding to the channel in the windows and central cavity of ZIFs. The average diameters of the cavities are 1.12, 1.54, and 0.80 nm in ZIF-90, ZIF-93, and ZIF-94, resp., while the average diameters of channels are between 0.55 and 0.60 nm. CO2 adsorption results show that ZIF-90 has the highest CO2 adsorption capacities (64.4 cm3 g-1 at 298 K and 104.7 cm3 g-1 at 273 K) at 1 bar, followed by ZIF-94 (57.9 cm3 g-1 at 298 K and 79.4 cm3 g-1 at 273 K) and ZIF-93 (41.5 cm3 g-1 at 298 K and 62.5 cm3 g-1 at 273 K). This shows inconsistency with the total pore volume but is in good agreement with relative volumes of pores smaller than 1.2 nm, which are 6.55, 2.06, and 5.60% for ZIF-90, ZIF-93, and ZIF-94, resp. Further investigation reveals that an even smaller pore size is required for CO2 adsorption under ultralow pressure. At a pressure of 0.1 bar, ZIF-94 exhibits an ultrahigh CO2 adsorption capacity (21.2 cm3 g-1 at 298 K and 32.1 cm3 g-1 at 273 K) compared with ZIF-93 (10.1 cm3 g-1 at 298 K and 14.9 cm3 g-1 at 273 K) and ZIF-90 (5.9 cm3 g-1 at 298 K and 11.6 cm3 g-1 at 273 K). These quantities coincide well with the relative volumes of pores smaller than 0.8 nm, which are 5.60, 2.06, and 1.18% for ZIF-94, ZIF-93, and ZIF-90, resp. Our results demonstrate that at atm. pressure, CO2 mols. are more effectively captured by micropores, while at extremely low pressures, CO2 mols. are mainly enriched around ultramicropores such as the channels and small cavities in ZIFs.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Recommanded Product: 1H-Imidazole-2-carbaldehyde

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Li, Mengwen team published research in Analytical Methods in 2020 | 10111-08-7

HPLC of Formula: 10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents. HPLC of Formula: 10111-08-7.

Li, Mengwen;Ao, Shen;Liang, Yueqi;Hao, Zhen;Hao, Xiaohui;Liu, Xueliang;Sun, Xinchao;Yang, Yunxu research published 《 The selective and sensitive detection of formaldehyde by ZIF-90-LWvia aza-Cope rearrangement》, the research content is summarized as follows. Formaldehyde (FA), as one of the simplest reactive carbonyl species (RCS), is widely known as an environmental toxin and carcinogen. In this work, a new ZIF-90 type material (ZIF-90-LW) was synthesized and investigated, which combines the two strategies of “2-aza-Cope rearrangement” and “MOF structure”, by the combination of a pre-functionalized 2-allylaminoimidazole ligand and Zn2+ salt under solvothermal conditions. From this, the hurdle of selectivity over other carbonyl compounds (RCS) could be overcome despite their similar electrophilic reactivities to FA, and a prominent fluorescence turn-on type signal was realized through the 2-aza-Cope rearrangement mechanism. A good linear relationship (R2 = 0.9979) was obtained by fitting the fluorescence intensity towards FA from 0 to 25 mM, and the detection limit of ZIF-90-LW for FA was 2.3 μM. In addition, it also showed potentially useful sensing ability for the detection of FA in the gas phase, and might therefore be used to rapidly detect FA with a response time of 28 s in the liquid phase. All of the above features clearly demonstrate that ZIF-90-LW has great potential for sensitive and selective recognition of FA in the environment.

HPLC of Formula: 10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Li, Mingmin team published research in Journal of the American Chemical Society in 2020 | 10111-08-7

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., SDS of cas: 10111-08-7

Imidazole is a five-membered heterocyclic moiety that possesses three carbon, two nitrogen, four hydrogen atoms, and two double bonds. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It is also known as 1, 3-diazole. It contains two nitrogen atoms, in which one nitrogen bear a hydrogen atom, and the other is called pyrrole type nitrogen. SDS of cas: 10111-08-7.

Li, Mingmin;Qiao, Shan;Zheng, Yunlong;Andaloussi, Yassin H.;Li, Xia;Zhang, Zhenjie;Li, Ang;Cheng, Peng;Ma, Shengqian;Chen, Yao research published 《 Fabricating Covalent Organic Framework Capsules with Commodious Microenvironment for Enzymes》, the research content is summarized as follows. Enzyme immobilization has been demonstrated to be a favorable protocol to promote industrialization of biomacromols. Despite tremendous efforts to develop new strategies and materials to realize this process, maintaining enzyme activity is still a formidable challenge. Herein we created a sacrificial templating method, using metal-organic frameworks (MOFs) as sacrificial templates to construct hollow covalent organic framework (COF) capsules for enzyme encapsulation. This strategy can provide a capacious microenvironment to unleash enzyme mols. The improved conformational freedom of enzymes, enhanced mass transfer, and protective effect against the external environment ultimately boosted the enzymic activities. We also found that this strategy possesses high versatility that is suitable for diverse biomacromols., MOF templates, and COF capsules. Moreover, the dimensions, pore sizes, and shell thickness of COF capsules can be conveniently tuned, allowing for customizing bioreactors for specific functions. For example, coencapsulation of different enzymes with synergistic functions were successfully demonstrated using this bioreactor platform. This study not only opens up a new avenue to overcome the present limitations of enzymic immobilization in porous matrixes but also provides new opportunities for construction of biomicrodevices or artificial organelles based on crystalline porous materials.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., SDS of cas: 10111-08-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Li, Shengnan team published research in CrystEngComm in 2021 | 10111-08-7

Application of C4H4N2O, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents. Application of C4H4N2O.

Li, Shengnan;Li, Ying;Yan, Bing research published 《 A turn-on fluorescence sensing strategy for rapid detection of flumequine in water environments using covalent-coordination functionalized MOFs》, the research content is summarized as follows. With the high output and large use of antibiotics in the process of aquaculture, pollution caused by antibiotics in water environments is becoming a thorny problem, and its ecol. risk has aroused widespread concern. In this work, the lanthanide hybrid material Eu@ZIF-90-PA is synthesized by a two-step post synthesis strategy using ZIF-90 with a modifiable group as a parent skeleton. Owing to its luminescence properties and water stability, the lanthanide functionalized material can be utilized as a novel “turn-on” fluorescent probe for quant. detection of flumequine in water environments. Addnl., the probe can not only be reused, but also quickly respond to flumequine within 30 s and the detection limit is 0.24 ppm. Even in the complex river water, the probe still exhibits an obvious luminescence enhancement effect with flumequine, which provides an efficient and convenient method for the detection of flumequine in real water. Finally, the fluorescence enhancement mechanism between flumequine and the probe is further explored.

Application of C4H4N2O, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Li, Wenjun team published research in Microchimica Acta in 2021 | 10111-08-7

Related Products of 10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. Their solubility in alcohol is lower than that in water and decreases with increasing molecular weight of the alcohols . Related Products of 10111-08-7.

Li, Wenjun;Chen, Siyu;Yang, Yue;Song, Yiju;Ma, Chaoyun;Qiao, Xiuwen;Hong, Chenglin research published 《 Ultrasensitive electrochemical immunosensor based on the signal amplification strategy of the competitive reaction of Zn2+ and ATP ions to construct a “signal on” mode GOx-HRP enzyme cascade reaction》, the research content is summarized as follows. A GOx/HRP@ZIF-90 nanomaterial is proposed by coating GOx and HRP in ZIF-90 using a bio-simulated mineralization method to improve the tolerance of the enzyme to the external environment. In the detection process, the ZIF-90 is turned on under mild conditions by the competitive reaction of ATP with Zn2+ and imidazole-2-carboxaldehyde (2-ICA), and the elec. signal of the system is amplified by the enzyme cascade reaction of GOx and HRP. Finally, based on the signal amplification strategy of the competitive reaction between Zn2+ and ATP to construct a “signal on” mode, electrochem. immunosensor of GOx-HRP enzyme-linked cascade reaction was prepared The proposed electrochem. immunosensor shows an excellent anal. performance when detecting CA-125, with good selectivity and stability, with a detection range of 0.1 pg mL-1-40 ng mL-1 and a detection limit of 0.05 pg mL-1. The test has been performed using chronoamperometry under a constant voltage of -0.4 V. The immunosensor also shows an excellent performance when analyzing human blood samples. The recovery of the immunosensor is 97.94-101.8%, with a relative standard deviation of 3.7-6.1%. The proposed sensor provides a novel idea for clin. use of GOx and HRP enzymes and a new method for the clin. detection of tumor markers.

Related Products of 10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Li, Xinyi team published research in Colloids and Surfaces, B: Biointerfaces in 2021 | 10111-08-7

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., SDS of cas: 10111-08-7

Imidazole based anticancer drug find applications in cancer chemotherapy. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC). SDS of cas: 10111-08-7.

Li, Xinyi;Hou, Shengxin;Chen, Jiucun;He, Cai-E.;Gao, Yong-E.;Lu, Yi;Jia, Die;Ma, Xianbin;Xue, Peng;Kang, Yuejun;Xu, Zhigang research published 《 Engineering silk sericin decorated zeolitic imidazolate framework-8 nanoplatform to enhance chemotherapy》, the research content is summarized as follows. The low therapeutic effect and strong side-effect are the major barriers for clin. chemotherapy. Herein, a pH-responsive nanoplatform based-silk sericin-zeolitic imidazolate framework-8 was designed for the delivery of chemotherapeutic doxorubicin (denoted as ZIF-8@DOX@SS, ZDS), which can overcome the limitation of poor circulation stability and unexpected drug leakage in blood circulation, producing a satisfactory chemotherapy. Concretely, ZIF-8 structure shows better stability and biocompatibility owing to the protection of a nature and non-toxic sericin protein. When it comes to low pH environment (e.g. in tumor cell microenvironment), the coordination effect in ZIF-8 will be broken and release DOX drugs. The nano-sized morphol. endow ZDS an efficient drug uptake and significant tumor permeability efficiency. Furthermore, the tumor-specific biodegradability makes ZDS possible to realize targeted and enhanced chemotherapy. Considering all the advantages in the study, this silk sericin-based nanosystem represent a promising strategy for the design of stimuli-responsive by using natural polymer to improve the treatment effect of chemotherapy.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., SDS of cas: 10111-08-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem