Category: 10111-08-7

The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with an increase of the alkyl chain length of the alcohols. Safety of 1H-Imidazole-2-carbaldehyde.

Joel, C.;Jim Livingston, D.;Biju Bennie, R.;Jeyanthi, D.;Vijay Solomon, Rajadurai research published 《 Designing bifunctional phenanthroimidazole chromophores for highly selective ratiometric chemosensing of Cu²⁺/F^– and Co²⁺/F^– ions in organic solvents》, the research content is summarized as follows. Two new phenanthroimidazole based highly sensitive and selective bifunctional probes 2-(1H-imidazol-2-yl)-1H-phenanthro[9,10-d]imidazole (PQIM) and 2-(1H-indol-3-yl)-1H-phenanthro[9,10-d]imidazole (PQIN) have been synthesized which could act as ratiometric sensors. Upon addition of analytes, the receptors exhibited pronounced fluoroionophoric behavior on account of internal charge transfer mechanism (ICT). The mol. sensing studies of both the ligands were explored using UV-visible and fluorescence spectroscopic techniques. It has been observed that the receptor PQIM shows better recognition behavior towards Cu2+/F- while the ligand PQIN exhibited enhanced sensing activity towards Co2+/F-. The binding stoichiometry of the receptor and cation/anion complex was probed to be 1:1 from Job’s plot which were further confirmed from ESI mass spectral techniques and ¹H NMR titrations Further, the binding interactions between these ions (Co²⁺, Cu²⁺ and F^–) with their resp. receptors are probed by d. functional theory calculations This study extends our knowledge on designing chem. compounds that could act as chemosensors in selective binding of certain anions/cations and their sensing mechanisms.

Safety of 1H-Imidazole-2-carbaldehyde, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. Their solubility in alcohol is lower than that in water and decreases with increasing molecular weight of the alcohols . Application In Synthesis of 10111-08-7.

Hu, Ming-Hao;Yu, Bing-Ying;Wang, Xiaodong;Jin, Guangyi research published 《 Drug-like biimidazole derivatives dually target c-MYC/BCL-2 G-quadruplexes and inhibit acute myeloid leukemia》, the research content is summarized as follows. Chemotherapy is the main approach for treating acute myeloid leukemia (AML). However, this therapy can cause severe side effects as well as drug resistance, hence calling for new therapeutic strategies. As c-MYC and BCL-2 are often overexpressed in AML, and synergism between c-MYC and BCL-2 promotes tumorigenesis, therefore, dual targeting of c-MYC/BCL-2 promoter G-quadruplexes (G4s) and then inhibiting the targeted gene expression would be a potential strategy in ALM treatment. In this work, in the search of dual ligands, we performed a screening assay with an inhouse, imidazole-based compound library. Consequently, two drug-like biimidazole derivatives were identified as selective c-MYC/BCL-2 G4 binders, of which, BIM-2 was selected as the candidate for inhibiting AML cell growth. Then, BIM-2 was demonstrated to downregulate both c-MYC and BCL-2 expression, and thereby cause cell cycle arrest at G0/G1 phase and apoptosis in AML cells. Furthermore, the possible end-stacking binding modes between BIM-2 and c-MYC/BCL-2 G4s were revealed by NMR and mol. docking studies. Accordingly, this study provides a new class of drug-like dual-selective c-MYC/BCL-2 G4 ligands for the potential treatment of AML.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Application In Synthesis of 10111-08-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Related Products of 10111-08-7.

Hunter, Kelly M.;Wagner, Jackson C.;Kalaj, Mark;Cohen, Seth M.;Xiong, Wei;Paesani, Francesco research published 《 Simulation Meets Experiment: Unraveling the Properties of Water in Metal-Organic Frameworks through Vibrational Spectroscopy》, the research content is summarized as follows. In nanoporous materials, host-guest interactions affect the properties and function of both adsorbent and adsorbate mols. Because of their structural and chem. diversity, metal-organic frameworks (MOFs), a common class of nanoporous materials, have been shown to be able to efficiently and, often, selectively adsorb various types of guest mols. In this study, we characterize the structure and dynamics of water confined in ZIF-90. Through the integration of exptl. and computational IR (IR) spectroscopy, we probe the structure of heavy water (D₂O) adsorbed in the pores, disentangling the fundamental framework-water and water-water interactions. The exptl. IR spectrum of D₂O in ZIF-90 displays a blue-shifted OD-stretch band compared to that of liquid D₂O. The anal. of the IR spectra simulated at both classical and quantum levels indicates that the D₂O mols. preferentially interact with the carbonyl groups of the framework and highlights the importance of including nuclear quantum effects and taking into account Fermi resonances for a correct interpretation of the OD-stretch band in terms of the underlying hydrogen-bonding motifs. Through a systematic comparison with the exptl. spectra, we demonstrate that computational spectroscopy can be used to gain quant., mol.-level insights into framework-water interactions that determine the water adsorption capacity of MOFs as well as the spatial arrangements of the water mols. inside the MOF pores which, in turn, are key to the design of MOF-based materials for water harvesting.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Related Products of 10111-08-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents. Synthetic Route of 10111-08-7.

Imyen, Thidarat;Znoutine, Emilie;Suttipat, Duangkamon;Iadrat, Ploychanok;Kidkhunthod, Pinit;Bureekaew, Sareeya;Wattanakit, Chularat research published 《 Methane Utilization to Methanol by a Hybrid Zeolite@Metal-Organic Framework》, the research content is summarized as follows. The development of an effective approach for methane utilization, especially methane conversion to methanol is a crucial challenge that has remained unsolved satisfactorily. Herein, we propose an alternative concept of methane utilization to methanol over a Fe-ZSM-5@ZIF-8. The concept is to use the designed composite as a dual catalyst, in which ZIF-8 and Fe-ZSM-5 act simultaneously as gas adsorbent and catalytic function, resp. In this case, methane can be adsorbed on ZIF-8 at 50°C, and subsequently converted to methanol at a moderate temperature (150°C) on Fe-ZSM-5. Interestingly, the promising catalytic performance is observed on Fe-ZSM-5@ZIF-8, whereas only trace amount of produced methanol is detected on isolated Fe-ZSM-5 and ZIF-8. Moreover, the designed composite also benefits a facile methanol desorption at hydrophobic surface of the composite. This first example opens new promising horizons in combined perspectives for gas storage and catalytic process applications.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Synthetic Route of 10111-08-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. Their solubility in alcohol is lower than that in water and decreases with increasing molecular weight of the alcohols . Recommanded Product: 1H-Imidazole-2-carbaldehyde.

Gopalakrishnan, Anjali Krishna;Angamaly, Shanty Antony;Pradeep, Savitha Devaswamparambil;Madhusoodhanan, Dhanya Thaikatt;Manoharan, Divya Kizhakkeppurath;Mohanan, Puzhavoorparambil Velayudhan research published 《 Imidazole Bound Schiff Base as Highly Selective “Turn-on” Fluorescence Sensor for Zn²⁺ and Colorimetric Kit for Co²⁺》, the research content is summarized as follows. An imidazole based Schiff base (2-[(1H-imidazole-2-ylmethylene)-amino]-4-methyl-phenol) (IMP), with an imine unit, has been designed and characterized by various standard methods. The evaluation of the probe as a fluorogenic sensor for Zn2+ and a chromogenic sensor for Co2+ has been rationalized in terms of the PET mechanism. In the presence of Zn2+, a light yellow colored solution of IMP with maximum absorption of 364 nm becomes bright yellow with maximum absorption of 410 nm and a measurable fluorescent signal at 612 nm with bathochromic enhancement. The sensitivity of the fluorescent based assay (6.78 x 10-9 M) for Zn2+ is far below the limit in the World Health Organization (WHO) guidelines for drinking water (7.6 x 10-5 M) and therefore it is capable of being a practical system for the monitoring of Zn2+ concentrations in aqueous samples. Moreover, IMP showed a highly selective colorimetric response to Co2+ by displayed an obvious pink color upon addition of metal solution immediately without any interference from other ions. These results provide a new approach for selectively recognizing the two most important trace elements in the human body simultaneously, for Zn2+ by emission spectra and Co2+ by the naked eye.

Recommanded Product: 1H-Imidazole-2-carbaldehyde, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. Their solubility in alcohol is lower than that in water and decreases with increasing molecular weight of the alcohols . Recommanded Product: 1H-Imidazole-2-carbaldehyde.

Guo, Fei;Li, Dongsheng;Ding, Rui;Gao, Jiaming;Ruan, Xuehua;Jiang, Xiaobin;He, Gaohong;Xiao, Wu research published 《 Constructing MOF-doped two-dimensional composite material ZIF-90@C₃N₄ mixed matrix membranes for CO₂/N₂ separation》, the research content is summarized as follows. Two-dimensional nanomaterials have the characteristics of high aspect ratio and high space utilization, which has huge potential advantages in gas separation In this work, g-C₃N₄ two-dimensional nanosheets with sieving pore structure were selected as templates and combined with ZIF-90 to construct a 0-dimensional/2-dimensional composite material ZIF-90@C₃N₄ (ZCN). The complete two-dimensional g-C₃N₄ nanosheets were stripped under acid etching conditions at 25°. ZIF-90 was distributed in an orderly manner on the two-dimensional nanosheets and the nanosheets were spread out due to the growth of ZIF-90 to provide more free volume The gas permeation experiment proved that the ZCN has a better CO₂/N₂ separation performance. The ZCN/Pebax mixed matrix membrane (MMM) with the optimized 8.0 wt% ZCN loading showed an improved CO₂ permeability of 110.5 Barrer and a CO₂ /N₂ selectivity of 84.4, surpassing the Robeson upper bound (2008). The results demonstrated that the designed composite filler with 2D nanosheets is an effective strategy to enhance gas separation performance of MMMs and verified the application potential in gas purification industry.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Recommanded Product: 1H-Imidazole-2-carbaldehyde

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with an increase of the alkyl chain length of the alcohols. Safety of 1H-Imidazole-2-carbaldehyde.

Guo, Shen;Zhang, Shu-Hua;Wang, Fei;Zhang, Jian research published 《 Syntheses of tetrahedral imidazolate frameworks with auxiliary ligand in DMSO》, the research content is summarized as follows. In the authors’ former work, the authors developed one kind of new tetrahedral imidazolate frameworks (TIF-Ax) by adding auxiliary unineg. linker into the zinc-imidazolate assembly in amide. Herein, (TIF-A4 to TIF-A8) were obtained from imidazolate derivatives and Zinc acetate (acetate as auxiliary ligands) in DMSO. Among them, Zn centers were coordinated by imidazolate derivatives to form 1-dimensional chain, differently, TIF-A4 exhibited 3-dimensional framework with dia topol. and TIF-A5 to TIF-A8 were 4-connected layer with sql topol. These results suggested that DMSO was a good solvent for the syntheses of new TIF-Ax. These compounds were characterized by single crystal XRD, powder XRD, FTIR and TG. The fluorescence of them were also tested.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Safety of 1H-Imidazole-2-carbaldehyde

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. SDS of cas: 10111-08-7.

Han, Zhaoyu;Qian, Yue;Wu, Yiyang;Cai, Yanfei;Jin, Jian;Yang, Zhaoqi research published 《 Metal-Organic Frameworks Deliver a Conjugate of Functional Oligonucleotides and Photosensitizer to Induce Apoptosis for Enhancing Chemotherapy》, the research content is summarized as follows. Metal-organic frameworks are highly porous and biodegradable and have found numerous applications in biomedicine. However, the traditional chemotherapy of MOF-drug delivery system remains a great challenge because of adverse side effects and cell tolerance. In this work, we have fabricated a hybrid drug delivery system based on ZIF-90 encapsulated with Doxorubicin (DOX) and Ce6-G3139 for enhanced chemotherapy. The released DOX can enter cell nucleus and trigger cell death. In addition, the G3139 binds to the anti-apoptotic gene Bcl-2 in tumor cells and related proteins are downregulated to inhibit cell proliferation. Meanwhile, the photosensitizer Ce6 carried by the nucleic acid will generate abundant reactive oxygen species under a near-IR (NIR) laser irradiation thus induces more cell apoptosis. It was worth mentioning that in vitro MTT test in the MCF-7 cells assays revealed that DOX@ ZIF-90/Ce6-G3139 nanoparticles possessed stronger anticancer capability than free DOX or DOX@ ZIF-90 nanoparticles indicating that the investigation offers an exciting new therapeutic strategy for the treatment of chemotherapy.

SDS of cas: 10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole based anticancer drug find applications in cancer chemotherapy. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC). HPLC of Formula: 10111-08-7.

Han, Zhentong;Zhao, Yaxin;Jiang, Haoji;Sheng, Ao;Li, Hao;Jia, Hao;Yun, Zhiyuan;Wei, Zhong;Wang, Heyun research published 《 (3-Aminopropyl) Triethoxysilane-Modified ZIF-90 Nanoparticle/Polydimethylsiloxane Mixed Matrix Membranes for Ethanol Recovery via Pervaporation》, the research content is summarized as follows. The present study eliminated nonselective defects by amending the MOF-based mixed matrix membrane (MMM) interface with (3-aminopropyl) triethoxysilane (APTES) via Schiff’s base reaction. This modification on the ZIF-90 nanoparticle surfaces enhanced the polydimethylsiloxane (PDMS) matrix interaction in the MMMs. Interfacial defects were then minimized through APTES-ZIF-90 nanoparticle surface alkoxy and PDMS chain hydroxyl group crosslinking. Enhanced chem. interactions between the nanoparticles and the polymeric matrix in the APTES-ZIF-90/PDMS MMMs resulted in higher interface compatibility and separation performance than the ZIF-90 nanoparticle MMMs, which ultimately improved its ethanol affinity and hydrophobicity. When the load of APTES-ZIF-90 nanoparticles was 15% and the temperature was 40°C, the pervaporation performance of APTES-ZIF-90/PDMS MMMs was optimal, the separation factor was 16.8, and the permeation flux was 223 g/(m²·h). Compared with pure PDMS, the separation factor and permeation flux increased by 91 and 67%, resp. In addition, stable APTES-ZIF-90/PDMS MMM pervaporation performance was observed after an optimal operation time of 120 h. Overall, the present work presented methods to optimize MOF-based MMMs for enhanced interface morphol. and separation performance for ethanol recovery.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., HPLC of Formula: 10111-08-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole based anticancer drug find applications in cancer chemotherapy. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC). Synthetic Route of 10111-08-7.

Hooper, Catherine A. J.;Cardo, Lucia;Craig, James S.;Melidis, Lazaros;Garai, Aditya;Egan, Ross T.;Sadovnikova, Viktoriia;Burkert, Florian;Male, Louise;Hodges, Nikolas J.;Browning, Douglas F.;Rosas, Roselyne;Liu, Fengbo;Rocha, Fillipe V.;Lima, Mauro A.;Liu, Simin;Bardelang, David;Hannon, Michael J. research published 《 Rotaxanating Metallo-supramolecular Nano-cylinder Helicates to Switch DNA Junction Binding》, the research content is summarized as follows. A class of rotaxane is created, not by encapsulating a conventional linear thread, but rather by wrapping a large cucurbit[10]uril macrocycle about a three-dimensional, cylindrical, nanosized, self-assembled supramol. helicate as the axle. The resulting pseudo-rotaxane is readily converted into a proper interlocked rotaxane by adding branch points to the helicate strands that form the surface of the cylinder (like branches and roots on a tree trunk). The supramol. cylinder that forms the axle is itself a member of a unique and remarkable class of helicate metallo-drugs that bind Y-shaped DNA junction structures and induce cell death. While pseudo-rotaxanation does not modify the DNA-binding properties, proper, mech.-interlocked rotaxanation transforms the DNA-binding and biol. activity of the cylinder. The ability of the cylinder to de-thread from the rotaxane (and thus to bind DNA junction structures) is controlled by the extent of branching: fully-branched cylinders are locked inside the cucurbit[10]uril macrocycle, while cylinders with incomplete branch points can de-thread from the rotaxane in response to competitor guests. The number of branch points can thus afford kinetic control over the drug de-threading and release.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Synthetic Route of 10111-08-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem